Publications

Abnormal meibum is associated with SREBF1 mutation and IFAP Syndrome-2

Lipid Composition and Thermotropic Properties of Meibum of Animal Models and Humans with Meibomian Gland Dysfunction

Aging Affects Lipid Homeostasis in Lacrimal Glands by Upregulating Lipogenesis and Changing Its Specificity

Comparative Analysis of Age-Associated Changes in Meibum Composition, Distribution, and Function in Mice With Altered Hyaluronan Expression

Biosynthesis of fatty aldehydes and alcohols in the eye and their role in meibogenesis

Meibomian gland lipid alterations and ocular surface sequela in Awat2 knockout murine model of meibomian gland dysfunction and evaporative dry eye disease

Comparative Characterization of Human Meibomian Glands, Free Sebaceous Glands, and Hair-Associated Sebaceous Glands Based on Biomarkers, Analysis of Secretion Composition, and Gland Morphology

Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface

Primary cilia control cellular patterning of Meibomian glands during morphogenesis but not lipid composition

Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis

Dysregulation of Lipid Metabolism in Aging Meibomian Glands and Its Molecular Markers

Comparative Biophysical Study of Meibomian Lipids of Wild Type and Soat1-Null Mice: Implications to Meibomian Gland Dysfunction and Dry Eye Disease

Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis

Probing dietary triacylglycerol metabolism and meibogenesis in mice: A stable isotope-labeled tracer liquid chromatography–tandem mass spectrometry study

Dynamic Changes in the Gene Expression Patterns and Lipid Profiles in the Developing and Maturing Meibomian Glands

Novel Lipids of the Rabbit Harderian Gland Improve Tear Stability in an Animal Model of Dry Eye Disease

Effects of aging on human meibum

Differential effects of dietary cholesterol and triglycerides on the lipid homeostasis in Meibomian glands

Physiological effects of inactivation and the roles of Elovl3/ELOVL3 in maintaining ocular homeostasis

Depletion of cholesteryl esters causes meibomian gland dysfunction-like symptoms in a soat1-null mouse model

Comprehensive profiling of Asian and Caucasian meibomian gland secretions reveals similar lipidomic signatures regardless of ethnicity

Delineating a novel metabolic high triglycerides-low waxes syndrome that affects lipid homeostasis in meibomian and sebaceous glands

Effects of sex (or lack thereof) on meibogenesis in mice (Mus musculus): Comparative evaluation of lipidomes and transcriptomes of male and female tarsal plates

Comparative transcriptomic and lipidomic analyses of human male and female meibomian glands reveal common signature genes of meibogenesis

On the pivotal role of Elovl3/ELOVL3 in meibogenesis and ocular physiology of mice

Cyclic change of fatty acid composition in meibum during the menstrual cycle

Meibomian glands, meibum, and meibogenesis

Dissecting lipid metabolism in meibomian glands of humans and mice: An integrative study reveals a network of metabolic reactions not duplicated in other tissues

Time-dependent degenerative transformations in the lipidome of chalazia

A role for ELOVL4 in the mouse meibomian gland and sebocyte cell biology

Tear film lipids

Biophysical and morphological evaluation of human normal and dry eye meibum using hot stage polarized light microscopy

The spectrophotometric sulfo-phospho-vanillin assessment of total lipids in human meibomian gland secretions

Differential scanning calorimetric evaluation of human meibomian gland secretions and model lipid mixtures: Transition temperatures and cooperativity of melting

Disruption and destabilization of meibomian lipid films caused by increasing amounts of ceramides and cholesterol

Toward an animal model of the human tear film: biochemical comparison of the mouse, canine, rabbit, and human meibomian lipidomes.

Evaluation and quantitation of intact wax esters of human meibum by gas-liquid chromatography-ion trap mass spectrometry

Erratum: Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye (Cornea (2011) 30 (308-314))

Effects of free fatty acids on meibomian lipid films

Lipidomics of human Meibomian gland secretions: Chemistry, biophysics, and physiological role of Meibomian lipids

Epidermal expression of an Elovl4 transgene rescues neonatal lethality of homozygous Stargardt disease-3 mice

Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye

The international workshop on meibomian gland dysfunction: Report of the subcommittee on tear film lipids and lipid-protein interactions in health and disease

On the presence of (O-acyl)-omega-hydroxy fatty acids and of their esters in human meibomian gland secretions

Comparative HPLC-MS n analysis of canine and human meibomian lipidomes: Many similarities, a few differences

On the presence and role of polar lipids in meibum

Meibomian lipid films and the impact of temperature

Fatty acid composition of cholesteryl esters of human meibomian gland secretions

Human tear film and meibum. Very long chain wax esters and (O-acyl)-omega-hydroxy fatty acids of meibum

The Meibomian Puzzle: Combining pieces together

Cholesteryl esters as a depot for very long chain fatty acids in human meibum

Adsorption of human tear lipocalin to human Meibomian lipid films

Historical brief on composition of human meibum lipids

Lipidomic analysis of human meibum using HPLC–MSn

Impact on ocular surface evaporation of an artificial tear solution containing hydroxypropyl guar.

On the lipid composition of human meibum and tears: Comparative analysis of nonpolar lipids

Inhibition of lipoxygenases and cyclooxygenases by linoleyl hydroxamic acid: Comparative in vitro studies

Understanding and analyzing meibomian lipids - A review

Lipids of human meibum: Mass-spectrometric analysis and structural elucidation

Liquid chromatography-mass spectrometric analysis of lipids present in human meibomian gland secretions

Increased evaporative rates in laboratory testing conditions simulating airplane cabin relative humidity: An important factor for dry eye syndrome

Pattern of vital staining and its correlation with aqueous tear deficiency and meibomian gland dropout

Research in dry eye: Report of the research subcommittee of the international Dry Eye WorkShop (2007)

Retinal pathology and skin barrier defect in mice carrying a Stargardt disease-3 mutation in elongase of very long chain fatty acids-4

Dihydroxydocosahexaenoic acids of the neuroprotectin D family: Synthesis, structure, and inhibition of human 5-lipoxygenase

A one-step method of 10,17-dihydro(pero)xydocosahexa-4Z,7Z,11E,13Z,15E,19Z- enoic acid synthesis by soybean lipoxygenase

Correlations in a change in aqueous tear evaporation with a change in relative humidity and the impact

Impact of evaporation on aqueous tear loss

On the structure and synthesis of neuroprotectin D1, a novel anti-inflammatory compound of the docosahexaenoic acid family

Novel oxylipins formed from docosahexaenoic acid by potato lipoxygenase-10(S)-hydroxydocosahexaenoic acid and 10,20- dihydroxydocosahexaenoic acid

Inhibition of potato lipoxygenase by linoleyl hydroxamic acid: Kinetic and EPR spectral evidence for a two-step reaction

The Biosynthetic gene cluster for the antitumor rebeccamycin: Characterization and generation of indolocarbazole derivatives

Characterization of the substrate aggregation state in 5-lipoxygenase oxidation of linoleic acid

Enzyme-catalyzed and enzyme-triggered pathways in dioxygenation of 1-monolinoleoyl-rac-glycerol by potato tuber lipoxygenase

Kharakteristika agregatnogo sostoianiia substrata v reaktsii 5-lipoksigenaznogo okisleniia linolevoikisloty.

The role of 4-hydroxy-TEMPO in the reaction of the linoleyl alcohol oxidation by potato tuber 5-lipoxygenase

Oxidation of linoleyl alcohol by potato tuber lipoxygenase: Kinetics and positional, stereo, and geometrical (cis, trans) specificity of the reaction

The role of phospholipids in regulation of activity of porcine leukocyte 12-lipoxygenase

Inhibition of linoleic acid oxidation by 12-lipoxygenase from porcine leucocytes by linoleyl-hydroxamic acid

Kinetic mechanism of linoleic acid oxidation by 5-lipoxygenase from Solatium tuberosum L

Oxidation of linoleyl alcohol by potato tuber lipoxygenase: Possible mechanism and the role of carboxylic group in substrate binding

Effect of linoleic acid lipoxygenase derivatives on functional activity of neutrophils

Vliianie lipoksigenaznykh proizvodnykh linolievoi kisloty na funktsional'nuiu aktivnost' neitrofilov.

Combined effect of phosphatidylinositol and linoleate-hydroxamic acid on 5-lipoxygenase

Phospholipids are possible regulators of lipoxygenase reaction on membrane level

Fatty acids hydroxamic derivatives as inhibitors of 5-lipoxygenase

Hydroxamic derivatives of saturated fatty acids as inhibitors of 5-lipoxygenase

Effect of linolenic acid and its hydroxamic derivative on 5-lipoxygenase

Influence of 1.25-dihydroxyvitamin D3 on soybean 15-lipoxygenase activity

12(S)-Hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-α in melanoma cells: Role of receptor-mediated hydrolysis of inositol phospholipids

Vliianie 13(S)-HPODE, lipoksigenaznogo produkta linolevoi kisloty na transport kal'tsiia i aktivnost' Na,K-ATFazy v sarkolemme miokarda.

Combined effect of phosphatidylcholine and linoleohydroxamic acid on 5-lipoxygenase activity

Kinetic characteristics of 5-lipoxygenase inhibition by 1,25-dihydroxyvitamin D3

Impact of 13(S)-HPODE, a lipoxygenase product of linoleic acid, on calcium transport and Na,K-ATPase activity in the myocardial sarcolemma

Erratum: 12(S)-Hydroxyeicosatetraenoic acid and 13(S)- hydroxyoctadecadienoic acid regulation of protein kinase C-α in melanoma cells: Role of receptor-mediated hydrolysis of inositol phospholipids (Cell (September 26, 1995) 92:20 (9323-9327))

On the interfacial phenomena in lipoxygenase catalysis.

12-Lipoxygenases and 12(S)-HETE: role in cancer metastasis

O mekhanizmakh izmeneniǐ koronarnogo sosudistogo soprotivleniia pri anafilakticheskom shoke.

The hormonally active vitamin D3 formulation, 1,25-dihydroxyvitamin D3, leukocyte lipoxygenase inhibitor

The unusual action of (R,S)‐2‐hydroxy‐2‐trifluoromethyl‐trans‐n‐octadec‐4‐enoic acid on 5‐lipoxygenase from potato tubers

Amfifil'nye alifaticheskie kisloty--aktivatory 5-lipoksigenazy. Adsorbtsionno-mitselliarnyǐ reguliatornyǐ mekhanizm.

Linoleate-hydroxamic acid: A suicide inhibitor of lipoxygenase

Aktivatsiia 5-lipoksigenazy lipofil'nymi n-alkilsoderzhashchimi kislotami--allostericheskiǐ protsess.

5-lipoksigenaza kartofelia. Kinetika okisleniia linolevoǐ kisloty.

Aktivnost' lipoksigenazy, vkliuchennoǐ v obrashchennye mitselly aérozolia OT v oktane.

Adsorption of proteins of the surfaces of modified silicas

Kataliticheskie svoǐstva vnekletochnykh fenoloksidaz vysshego bazidiomitseta Pleurotus ostreatus (Fr.) Kumm.

Stabil'nost' i kataliticheskie svoǐstva o-difenoloksidazy. 2. Okislenie monofenolov.

Stabil'nost' i kataliticheskie svoǐstva o-difenoloksidazy. 1. Okislenie o-difenolov.

Inaktivatsiia o-difenoloksidazy v protsesse reaktsii okisleniia pirokatekhina.

Metod opredeleniia aktivnosti o-difenoloksidazy v reaktsii okisleniia pirokatekhina.