People

Meet the Principal Investigator

Lindsay Cowell, Ph.D.

Lindsay Cowell, Ph.D.

Associate Professor

Education

Postdoctoral training in Immunology
Duke University Medical Center, Durham, North Carolina

Ph.D. in Biomathematics
North Carolina State University, Raleigh, North Carolina

M.S. in Biomathematics
North Carolina State University, Raleigh, North Carolina

B.A. in Education
University of North Carolina at Chapel Hill, North Carolina

Experience and Research Interests

Dr. Cowell has built a research program focused on the development of bioinformatics and computational biology methods for studying the immune system and infectious diseases.  In particular, her work has focused on the somatic diversification of antigen receptor-encoding genes and the development of computable representations of qualitative biological and clinical information. Within each of these areas, she has developed projects that emphasize methodologic development as well as projects focused on answering specific biological questions. 

Current Lab Members

Min Soo Kim, M.S.

Computational Biologist II

Education

M.S. in Medical Informatics and Bioinformatics
San Diego State University, California

B.S. in Biochemistry
York University, Toronto, Ontario, Canada

Experience and Research Interests

I started my research doing protein structure modeling using mass spectrometry and 2D NMR data during my senior undergraduate year at York University. I continued my research on protein structure modeling studying monoclonal antibody/antigen binding with X-ray crystallography and molecular dynamics modeling techniques. For my master’s research,  I worked on a large-scale Next Generation Sequencing (NGS) project for identifying the genetic mechanism of drug resistance in tuberculosis. My proficiencies include protein structure modeling, NGS data analysis, programming in various languages, and high-performance computing environments. 

Inimary Toby, Ph.D.

Computational Biologist II

Education

Postdoctoral training, FAA- Civil Aerospace Medical Institute
Genomics Team, Oklahoma City, Oklahoma

Ph.D. in Biomedical Sciences
The Ohio State University, Columbus, Ohio

B.A. in Chemistry and Environmental Sciences
The University of Tennessee Knoxville, Tennessee

Experience and Research Interests

After my undergraduate studies, I worked for a Biotech company studying waste disposal methods in soil.  Following that, I pursued graduate studies and my thesis research project was focused on pulmonary hypertension.  We utilized cells and animals to study disease pathogenesis and explore therapeutic options.  Subsequently, my postdoctoral training was concentrated on genomics, and specifically, I worked on a project using a combination of wet bench and computational approaches to analyze blood samples from clinical studies.  Later, I joined a Bioinformatics core facility and began managing data obtained from sequencing studies for clinical cases and various microorganisms.  My research interests are in utilizing computational methods to facilitate the analysis of big data and particularly developing strategies to enable the accurate interpretation of genome data.

Collaborators

    Russ Waitman, Ph.D.
    Director of Medical Informatics
    University of Kansas Medical Center

    Nancy Monson, Ph.D.
    Associate Professor, Departments of Neurology & Neurotherapeutics
    UT Southwestern Medical Center

    Tom Kepler, Ph.D.
    Professor, Dept. of Microbiology
    Boston University

    David Schatz, Ph.D.
    Professor, Departments of Immunobiology and Molecule Biophysics & Biochemistry
    Yale University

    Barry Smith, Ph.D.
    Director, National Center for Ontological Research
    University at Buffalo

    Tom Kepler, Ph.D.
    Professor, Dept. of Microbiology
    Boston University

    Scott Boyd, M.D., Ph.D.
    Assistant Professor, Department of Pathology
    Stanford University Medical Center

    Andrew Fire, Ph.D.
    George D. Smith Professor in Molecular and Genetic Medicine and Professor of Genetics
    Stanford University School of Medicine

    John Fonner, Ph.D.
    Research Associate, Texas Advanced Computing Center
    The University of Texas at Austin

    Jeffrey Frelinger, Ph.D.
    Professor, Department of Immunology
    The University of Arizona College of Medicine

    Steven H Kleinstein, Ph.D.
    Associate Professor, Department of Pathology
    Yale University

    Nancy Monson, Ph.D.
    Associate Professor, Departments of Neurology & Neurotherapeutics
    UT Southwestern Medical Center

    Michel C. Nussenzweig, M.D., Ph.D.
    Investigator, Laboratory of Molecular Immunology
    Rockefeller University

    Richard H. Scheuermann, Ph.D.
    Director of Informatics
    J. Craig Venter Institute

    Jonathan S. Serody, M.D.
    Elizabeth Thomas Professor of Medicine, Microbiology, and Immunology,
    The University of North Carolina at Chapel Hill