Complete list of publications

Featured Publications

Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.

Deja S, Fletcher JA, Kim CW, Kucejova B, Fu X, Mizerska M, Villegas M, Pudelko-Malik N, Browder N, Inigo-Vollmer M, Menezes CJ, Mishra P, Berglund ED, Browning JD, Thyfault JP, Young JD, Horton JD, Burgess SC, 2024 Mar Cell Metab

Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization.

Onodera T, Wang MY, Rutkowski JM, Deja S, Chen S, Balzer MS, Kim DS, Sun X, An YA, Field BC, Lee C, Matsuo EI, Mizerska M, Sanjana I, Fujiwara N, Kusminski CM, Gordillo R, Gautron L, Marciano DK, Hu MC, Burgess SC, Susztak K, Moe OW, Scherer PE, 2023 Oct Nat Commun 1 14 6531

Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice.

Yiew NKH, Deja S, Ferguson D, Cho K, Jarasvaraparn C, Jacome-Sosa M, Lutkewitte AJ, Mukherjee S, Fu X, Singer JM, Patti GJ, Burgess SC, Finck BN, 2023 Nov iScience 11 26 108196

Krebs takes a turn at cell differentiation.

Deja S, Crawford PA, Burgess SC, 2022 May Cell Metab 5 34 658-660

Ins and Outs of the TCA Cycle: The Central Role of Anaplerosis.

Inigo M, Deja S, Burgess SC, 2021 Jul Annu Rev Nutr

INCA 2.0: A tool for integrated, dynamic modeling of NMR- and MS-based isotopomer measurements and rigorous metabolic flux analysis.

Rahim M, Ragavan M, Deja S, Merritt ME, Burgess SC, Young JD, 2021 Dec Metab Eng

In Vivo Estimation of Ketogenesis Using Metabolic Flux Analysis-Technical Aspects and Model Interpretation.

Deja S, Kucejova B, Fu X, Browning JD, Young JD, Burgess S, 2021 Apr Metabolites 5 11

Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver.

Deja S, Fu X, Fletcher JA, Kucejova B, Browning JD, Young JD, Burgess SC, 2019 Dec Metab. Eng.

Targeted Determination of Tissue Energy Status by LC-MS/MS.

Fu X, Deja S, Kucejova B, Duarte JAG, McDonald JG, Burgess SC, 2019 Apr Anal. Chem.

Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver.

Cappel DA, Deja S, Duarte JAG, Kucejova B, Iñigo M, Fletcher JA, Fu X, Berglund ED, Liu T, Elmquist JK, Hammer S, Mishra P, Browning JD, Burgess SC, 2019 Apr Cell Metab.

Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver.

Fletcher JA, Deja S, Satapati S, Fu X, Burgess SC, Browning JD, 2019 Apr JCI Insight 5

The NQO1 bioactivatable drug, ?-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism.

Silvers MA, Deja S, Singh N, Egnatchik RA, Sudderth J, Luo X, Beg MS, Burgess SC, DeBerardinis RJ, Boothman DA, Merritt ME 2017 11 J. Biol. Chem. 44 292 18203-18216

Persistent fasting lipogenesis links impaired ketogenesis with citrate synthesis in humans with nonalcoholic fatty liver.

Fu X, Fletcher JA, Deja S, Inigo-Vollmer M, Burgess SC, Browning JD, 2023 May J Clin Invest 9 133

Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and glycerol-mediated gluconeogenesis in mice.

Yiew NKH, Ferguson D, Cho K, Deja S, Jarasvaraparn C, Lutkewitte AJ, Mukherjee S, Fu X, Singer JM, Patti GJ, Burgess SC, Finck BN, 2023 Feb bioRxiv

Gender-Specific Metabolomics Approach to Kidney Cancer.

Deja S, Litarski A, Mielko KA, Pudelko-Malik N, Wojtowicz W, Zabek A, Szydelko T, Mlynarz P, 2021 Nov Metabolites 11 11

Measurement of lipogenic flux by deuterium resolved mass spectrometry.

Fu X, Deja S, Fletcher JA, Anderson NN, Mizerska M, Vale G, Browning JD, Horton JD, McDonald JG, Mitsche MA, Burgess SC, 2021 06 Nat Commun 1 12 3756

LC-QTOF-MS and 1H NMR Metabolomics Verifies Potential Use of Greater Omentum for Klebsiella pneumoniae Biofilm Eradication in Rats.

Teul J, Deja S, Celinska-Janowicz K, Zabek A, Mlynarz P, Barc P, Junka A, Smutnicka D, Bartoszewicz M, Palka J, Miltyk W, 2020 May Pathogens 5 9

Cytosolic Phosphoenolpyruvate Carboxykinase as a Cataplerotic Pathway in the Small Intestine.

Potts A, Uchida A, Deja S, Berglund ED, Kucejova B, Duarte JAG, Fu X, Browning JD, Magnuson MA, Burgess SC 2018 Apr Am. J. Physiol. Gastrointest. Liver Physiol.

Serum and urine 1H NMR-based metabolomics in the diagnosis of selected thyroid diseases.

Wojtowicz W, Zabek A, Deja S, Dawiskiba T, Pawelka D, Glod M, Balcerzak W, Mlynarz P 2017 Aug Sci Rep 1 7 9108

Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.

Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD 2017 Aug Cell Metab. 2 26 394-406.e6

Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.

Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD 2017 09 Cell Metab. 3 26 576

Application of (1)H NMR-based serum metabolomic studies for monitoring female patients with rheumatoid arthritis.

Zabek A, Swierkot J, Malak A, Zawadzka I, Deja S, Bogunia-Kubik K, Mlynarz P 2016 Jan J Pharm Biomed Anal 117 544-50

Metabolomics of chronic obstructive pulmonary disease and obstructive sleep apnea syndrome: response to Maniscalco and Motta.

Mlynarz P, Deja S, Stanimirova I, Zabek A, Barg W, Jankowska R 2016 Metabolomics 12 33

Metabolomics of Human Amniotic Fluid and Maternal Plasma during Normal Pregnancy.

Orczyk-Pawilowicz M, Jawien E, Deja S, Hirnle L, Zabek A, Mlynarz P 2016 PLoS ONE 4 11 e0152740

1H NMR-based metabolic profiling for evaluating poppy seed rancidity and brewing.

Jawien E, Zabek A, Deja S, Lukaszewicz M, Mlynarz P 2015 Dec Cell. Mol. Biol. Lett. 5 20 757-72

Fusion of the 1H NMR data of serum, urine and exhaled breath condensate in order to discriminate chronic obstructive pulmonary disease and obstructive sleep apnea syndrome.

Zabek A, Stanimirova I, Deja S, Barg W, Kowal A, Korzeniewska A, Orczyk-Pawilowicz M, Baranowski D, Gdaniec Z, Jankowska R, Mlynarz P 2015 Metabolomics 6 11 1563-1574

Metabolomics provide new insights on lung cancer staging and discrimination from chronic obstructive pulmonary disease.

Deja S, Porebska I, Kowal A, Zabek A, Barg W, Pawelczyk K, Stanimirova I, Daszykowski M, Korzeniewska A, Jankowska R, Mlynarz P 2014 Nov J Pharm Biomed Anal 100 369-380

Rapid determination of ibotenic acid and muscimol in human urine.

Deja S, Jawien E, Jasicka-Misiak I, Halama M, Wieczorek P, Kafarski P, Mlynarz P 2014 Nov Magn Reson Chem 11 52 711-4

Serum and urine metabolomic fingerprinting in diagnostics of inflammatory bowel diseases.

Dawiskiba T, Deja S, Mulak A, Zabek A, Jawien E, Pawelka D, Banasik M, Mastalerz-Migas A, Balcerzak W, Kaliszewski K, Skóra J, Barc P, Korta K, Pormanczuk K, Szyber P, Litarski A, Mlynarz P 2014 Jan World J. Gastroenterol. 1 20 163-74

Chemometrics as a tool of origin determination of Polish monofloral and multifloral honeys.

Zielinski L, Deja S, Jasicka-Misiak I, Kafarski P 2014 Apr J. Agric. Food Chem. 13 62 2973-81

Do differences in chemical composition of stem and cap of Amanita muscaria fruiting bodies correlate with topsoil type?

Deja S, Wieczorek PP, Halama M, Jasicka-Misiak I, Kafarski P, Poliwoda A, Mlynarz P 2014 PLoS ONE 12 9 e104084

1H NMR-based metabolomics studies of urine reveal differences between type 1 diabetic patients with high and low HbAc1 values.

Deja S, Barg E, Mlynarz P, Basiak A, Willak-Janc E 2013 Sep J Pharm Biomed Anal 83 43-8

Differences in metabolic profiles of planktonic and biofilm cells in Staphylococcus aureus - (1)H Nuclear Magnetic Resonance search for candidate biomarkers.

Junka AF, Deja S, Smutnicka D, Szymczyk P, Ziólkowski G, Bartoszewicz M, Mlynarz P 2013 Acta Biochim. Pol. 4 60 701-6

Follicular adenomas exhibit a unique metabolic profile. ?H NMR studies of thyroid lesions.

Deja S, Dawiskiba T, Balcerzak W, Orczyk-Pawilowicz M, Glód M, Pawelka D, Mlynarz P 2013 PLoS ONE 12 8 e84637

[Application of metabolomic in COPD diagnosing].

Mlynarz P, Barg W, Deja S, Jankowska R 2012 Oct Pol. Merkur. Lekarski 196 33 207-12