Discoveries in Print

Featured Discoveries

Skin androgens regulate Staphylococcus aureus pathogenicity via quorum sensing

John, M.S., Chinnappan, M., Sturges, C.I. et al. Nat Microbiol 11, 704–717 (2026)

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Cutaneous Hormone Production Is Distinct between Anatomical Sites and between Males and Females

J. Pineider, K. M. Eckert, J. G. McDonald, T. A. Harris-Tryon, Journal of Investigative Dermatology, Volume 143, Issue 4, 2023,

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Interleukins 4 and 13 drive lipid abnormalities in skin cells through regulation of sex steroid hormone synthesis

C. Zhang, M. Chinnappan, C.A. Prestwood, M. Edwards, M. Artami, B.M. Thompson, K.M. Eckert, G. Vale, C.C. Zouboulis, J.G. McDonald, & T.A. Harris-Tryon, Proc. Natl. Acad. Sci. U.S.A. 118 (38)

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Small proline-rich proteins (SPRRs) are epidermally produced antimicrobial proteins that defend the cutaneous barrier by direct bacterial membrane disruption

C. Zhang, Z. Hu, A. G. Lone, M. Artami, M. Edwards, C. C. Zouboulis, M. Stein, T. A. Harris-Tryon, 2022, eLife

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Saprophytic bacteria and fungi colonize stearoyl coenzyme-A desaturase-1 knockout skin

Pyle HJ, Artami M, Edwards M, et al. Exp Dermatol. 2023;32:78-84

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Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin

Harris T, Gattu S, Propheter D, Hooper L et. al, Cell Host & Microbe, 2019; 25, 777-788.e8

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Assessment of the Cutaneous Hormone Landscapes and Microbiomes in Vulvar Lichen Sclerosus

H. J. Pyle, J. C. Evans, M. Artami, P. Raj, S. Sridharan, C. Arana, K. M. Eckert, J. G. McDonald, T. A. Harris-Tryon, M. M. Mauskar, Journal of Investigative Dermatology, Volume 144, Issue 8, 2024,

Featured Reviews

Microbiota and maintenance of skin barrier function

Tamia A. Harris-Tryon, Elizabeth A. Grice , Science376,940-945(2022)

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Skin immunity: dissecting the complex biology of our body's outer barrier

C. Zhang, G. R. Merana, T. A. Harris-Tryon, T. C. Scharschmidt, Mucosal Immunology, Volume 15, Issue 4, 2022

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Cutaneous Hormone Sampling and Analysis for Dermatologic Research

C. I. Sturges, S.Jain, M. Velasquez, H. Gedamu, J. Komarovsky, J. G. McDonald, T. A. Harris-Tryon, Journal of Investigative Dermatology, Volume 145, Issue 8, 2025

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The human skin microbiome in health

M. A. MacGibeny, S. Adjei, H. Pyle, C. G. Bunick, M. Ghannoum, A. Grada, T. A. Harris-Tryon, S. K. Tyring, H. H. Kong, Journal of the American Academy of Dermatology, Volume 93, Issue 2, 2025,

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The human skin microbiome in health

M. A. MacGibeny, S. Adjei, H. Pyle, C. G. Bunick, M. Ghannoum, A. Grada, T. A. Harris-Tryon, S. K. Tyring, H. H. Kong, Journal of the American Academy of Dermatology, Volume 93, Issue 2, 2025,

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Novel mechanisms of microbial crosstalk with skin innate immunity

Fritzlaine C. Roche and Tamia A. Harris-Tryon

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Illuminating the Role of Vitamin A in Skin Innate Immunity and the Skin Microbiome: A Narrative Review

Fritzlaine C. Roche and Tamia A. Harris-Tryon, Nutrients 2021, 13(2), 302

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A Staphylococcus Path to Improved Therapeutics in Atopic Dermatitis

Tamia A. Harris-Tryon, Shai Bel, JAMA Dermatol, 2021

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Further Publications

For a comprehensive list of Dr. Harris Tryon's publications, click here.