Publications

Comparing the effects of four common drug classes on the progression of mild cognitive impairment to dementia using electronic health records

Xu J, Wang F, Zang C, Zhang H, Niotis K, Liberman AL, Stonnington CM, Ishii M, Adekkanattu P, Luo Y, Mao C, Rasmussen LV, Xu Z, Brandt P, Pacheco JA, Peng Y, Jiang G, Isaacson R, Pathak J 2023 Dec Scientific reports 13

What is good for the heart is good for brain glucose metabolism

Ishii M 2023 Sep The Lancet Healthy Longevity 4 e448-e449

Sexually Dimorphic Association of Circulating Plasminogen Activator Inhibitor-1 Levels and Body Mass Index with Cerebrospinal Fluid Biomarkers of Alzheimer's Pathology in Preclinical Alzheimer's Disease

Eruysal E, Ravdin L, Zhang C, Kamel H, Iadecola C, Ishii M 2023 Journal of Alzheimer's Disease 91 1073-1083

Midlife dyslipidaemia as a modifiable risk factor for later-life dementia

Ishii M 2021 Aug The Lancet Healthy Longevity 2 e453-e454

Pituitary Apoplexy

Seitz AP, Ishii M 2021 Jan 259-274

A Novel Neurovascular Liaison Governing the Blood-Brain Barrier

Ishii M, Iadecola C 2020 Jul Neuron 107 205-207

Risk factor for Alzheimer's disease breaks the blood-brain barrier

Ishii M, Iadecola C 2020 May Nature 581 31-32

Plasma lipocalin-2 levels in the preclinical stage of Alzheimer's disease

Eruysal E, Ravdin L, Kamel H, Iadecola C, Ishii M 2019 Dec Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring 11 646-653

Amyloid-beta modulates low-threshold activated voltagegated l-type calcium channels of arcuate neuropeptide y neurons leading to calcium dysregulation and hypothalamic dysfunction

Ishii M, Hiller AJ, Pham L, McGuire MJ, Iadecola C, Wang G 2019 Oct Journal of Neuroscience 39 8816-8825

Apolipoprotein B as a New Link between Cholesterol and Alzheimer Disease

Ishii M 2019 Jul JAMA neurology 76 751-752

McLeod syndrome: Five new pedigrees with novel mutations

Weaver J, Sarva H, Barone D, Bobker S, Bushara K, Hiller A, Ishii M, Jankovic J, Lakhani S, Niotis K, Scharre DW, Tuite P, Stutz A, Westhoff CM, Walker RH 2019 Jul Parkinsonism and Related Disorders 64 293-299

Retinol Binding Protein 4 Levels Are Not Altered in Preclinical Alzheimer's Disease and Not Associated with Cognitive Decline or Incident Dementia

Ishii M, Kamel H, Iadecola C 2019 Journal of Alzheimer's Disease 67 257-263

Disorders of body weight, sleep and circadian rhythm as manifestations of hypothalamic dysfunction in Alzheimer’s disease

Hiller AJ, Ishii M 2018 Dec Frontiers in Cellular Neuroscience 12

Endocrine emergencies with neurologic manifestations

Ishii M 2017 CONTINUUM Lifelong Learning in Neurology 23 778-801

Adipocyte-derived factors in age-related dementia and their contribution to vascular and Alzheimer pathology

Ishii M, Iadecola C 2016 May Biochimica et Biophysica Acta - Molecular Basis of Disease 1862 966-974

Leptin Dysfunction and Alzheimer’s Disease: Evidence from Cellular, Animal, and Human Studies

McGuire MJ, Ishii M 2016 Mar Cellular and Molecular Neurobiology 36 203-217

Metabolic and Non-Cognitive Manifestations of Alzheimers Disease: The Hypothalamus as Both Culprit and Target of Pathology

Ishii M, Iadecola C 2015 Nov Cell Metabolism 22 761-776

Neurologic complications of nondiabetic endocrine disorders

Ishii M 2014 Jun CONTINUUM Lifelong Learning in Neurology 20 560-579

Amyloid β-Related Central Nervous System Angiitis Presenting With an Isolated Seizure

Ishii M, Kamel H, Iadecola C, Navi BB, Lavi E, Gupta A 2014 Apr The Neurohospitalist 4 86-89

Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide y neurons

Ishii M, Wang G, Racchumi G, Dyke JP, Iadecola C 2014 Journal of Neuroscience 34 9096-9106

Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory

Nagata-Kuroiwa R, Furutani N, Hara J, Hondo M, Ishii M, Abe T, Mieda M, Tsujino N, Motoike T, Yanagawa Y, Kuwaki T, Yamamoto M, Yanagisawa M, Sakurai T 2011 PloS one 6

Fasting-Induced Hypothermia and Reduced Energy Production in Mice Lacking Acetyl-CoA Synthetase 2

Sakakibara I, Fujino T, Ishii M, Tanaka T, Shimosawa T, Miura S, Zhang W, Tokutake Y, Yamamoto J, Awano M, Iwasaki S, Motoike T, Okamura M, Inagaki T, Kita K, Ezaki O, Naito M, Kuwaki T, Chohnan S, Yamamoto TT, Hammer RE, Kodama T, Yanagisawa M, Sakai J 2009 Feb Cell Metabolism 9 191-202

Effect of neuropeptide B on feeding behavior is influenced by endogenous corticotropin-releasing factor activities

Aikawa S, Ishii M, Yanagisawa M, Sakakibara Y, Sakurai T 2008 Nov Regulatory Peptides 151 147-152

The NPB/NPW neuropeptide system and its role in regulating energy homeostasis, pain, and emotion

Hondo M, Ishii M, Sakurai T 2008 239-256

Distribution of neuropeptide W immunoreactivity and mRNA in adult rat brain

Kitamura Y, Tanaka H, Motoike T, Ishii M, Williams SC, Yanagisawa M, Sakurai T 2006 Jun Brain Research 1093 123-134

Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity

Ishii M, Fei H, Friedman JM 2003 Sep Proceedings of the National Academy of Sciences of the United States of America 100 10540-10545

Mechanism-based inhibition of the melatonin rhythm enzyme: Pharmacologic exploitation of active site functional plasticity

Khalil EM, De Angelis J, Ishii M, Cole PA 1999 Oct Proceedings of the National Academy of Sciences of the United States of America 96 12418-12423

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richarson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M 1998 Mar Cell 92 1 page following 696

Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M 1998 Feb Cell 92 573-585