People

The Li Lab was established in 2017 with just two members and has since grown to 11. Our research focuses on cholesterol metabolism and transport, developmental signaling pathways, and integrating biochemistry with structural biology. We are currently expanding our work to include animal models, which has provided us with diverse perspectives on our research.

Group of 12 lab members outside with large trees in the background.

Meet the Principal Investigator

Xiaochun Li, Ph.D.

Xiaochun Li, Ph.D.

Professor

Faculty Profile

Dr. Li received his B.S. in 2008 from Tsinghua University in China and finished his Ph.D. training in Structural Biology under the mentorship of Dr. Yigong Shi in 2012. His postdoctoral studies as a Life Science Research Foundation Fellow were conducted with Dr. Günter Blobel, 1999 Nobel Laureate in Physiology or Medicine, at Rockefeller University. He went on to win the Tri-Institutional (Memorial Sloan Kettering Cancer Research Center, Rockefeller University, and Weill Cornell Medicine) Breakout Prize for Junior Investigators.

In 2017, he joined the faculty at UT Southwestern Medical Center. He is an Assistant Professor and a Rita C. and William P. Clements, Jr. Scholar in Biomedical Research in the Department of Molecular Genetics under the leadership of Drs. Joseph Goldstein and Michael Brown, 1985 Nobel Laureates in Physiology or Medicine. Here he will continue using structural techniques to study the pathways of cholesterol metabolism and lysosomal storage diseases.

Phone: (214) 648-3821

Current Lab Members

Leticia Esparza

Sr. Research Associate/Lab Manager
Email

Leticia Esparza

Alex Hatton

Research Assistant II
Email

Alex Hatton

Qinli Hu, Ph.D.

Postdoctoral Researcher
Email

Qinli Hu, Ph.D.

Chang Min Kim, Ph.D.

Postdoctoral Researcher
Email

Chang Min Kim

Dongyu Li, Ph.D.

Postdoctoral Researcher
Email

Dongyu Li

Harris Shaikh

Research Technician
Email

Harris Shaikh

Philip Schmiege, Ph.D.

R&D Senior Scientist
Email

Philip Schmiege

Nick Sun, Ph.D.

Postdoctoral Researcher
Email

Nick Sun

Rong Wang, Ph.D.

Postdoctoral Researcher
Email

Rong Wang

Ling Zhang, Ph.D.

Postdoctoral Researcher

Email

Ling Zhang

Mochi

Lab Mascot

Mochi

Lab Alumni

    Hongwen Chen, Ph.D.

    Postdoctoral Researcher, 2019–2024

    Post-lab:

    Professor, Shanghai Jiao Tong University

    Hongwen Chen

    Tao Long, Ph.D.

    Postdoctoral Researcher, 2017-2024

    Post-Lab:

    Professor, Wuhan University

    Tao Long

    Xiaofeng Qi, Ph.D.

    Postdoctoral Researcher, 2017–2023

    Post-lab: 

    Tenure track Assistant Professor, Department of Molecular Biology, UT Southwestern
    Email

    Xiaofeng Qi

    Yang Liu

    Graduate Student, 2019–2023

    Post-lab: 

    Postdoctoral Researcher in Feng Zhang's lab, MIT

    Yang Liu

    Michael Fine, Ph.D.

    Research Fellow, 2018–2021

    Post-lab: 

    Instructor, UT Southwestern

    Michael Fine

    Ryan DeBose-Boyd

    Research Technician, 2019–2020

    Post-lab: 

    Ph.D. student at Baylor College of Medicine

    Ryan DeBose-Boyd

    Lucas Friedberg

    Research Technician, 2019–2020

    Post-lab: 

    Master's student at Miami University

    Lucas Friedberg

    Abdirahman Hassan

    Research Assistant, 2018–2020

    Post-lab: 

    M.D. student at Royal College of Surgeons in Ireland

    Abdirahman Hassan

    Haity Qin

    Research Assistant, 2020–2024

    Post-lab: 

    MSTP student at UT Health San Antonio

    Haity Qin

    Group Photos