Publications

Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology

Author Collaboration JL, Li TT, Chen X, Huo D, Arifuzzaman M, Qiao S, Jin WB, Shi H, Li XV, Iliev ID, Artis D, Guo CJ 2024 May Cell Host and Microbe 32 661-675.e10

Author Correction: Immune regulation by fungal strain diversity in inflammatory bowel disease (Nature, (2022), 603, 7902, (672-678), 10.1038/s41586-022-04502-w)

Li XV, Leonardi I, Putzel GG, Semon A, Fiers WD, Kusakabe T, Lin WY, Gao IH, Doron I, Gutierrez-Guerrero A, DeCelie MB, Carriche GM, Mesko M, Yang C, Naglik JR, Hube B, Scherl EJ, Iliev ID 2022 Aug Nature 608 E21

Immune regulation by fungal strain diversity in inflammatory bowel disease

Li XV, Leonardi I, Putzel GG, Semon A, Fiers WD, Kusakabe T, Lin WY, Gao IH, Doron I, Gutierrez-Guerrero A, DeCelie MB, Carriche GM, Mesko M, Yang C, Naglik JR, Hube B, Scherl EJ, Iliev ID 2022 Mar Nature 603 672-678

Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity

Leonardi I, Gao IH, Lin WY, Allen M, Li XV, Fiers WD, De Celie MB, Putzel GG, Yantiss RK, Johncilla M, Colak D, Iliev ID 2022 Mar Cell 185 831-846.e14

Genetic manipulation of gut microbes enables single-gene interrogation in a complex microbiome

Jin WB, Li TT, Huo D, Qu S, Li XV, Arifuzzaman M, Lima SF, Shi HQ, Wang A, Putzel GG, Longman RS, Artis D, Guo CJ 2022 Feb Cell 185 547-562.e22

Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn’s disease

Doron I, Mesko M, Li XV, Kusakabe T, Leonardi I, Shaw DG, Fiers WD, Lin WY, Bialt-DeCelie M, Román E, Longman RS, Pla J, Wilson PC, Iliev ID 2021 Dec Nature microbiology 6 1493-1504

Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies

Doron I, Leonardi I, Li XV, Fiers WD, Semon A, Bialt-DeCelie M, Migaud M, Gao IH, Lin WY, Kusakabe T, Puel A, Iliev ID 2021 Feb Cell 184 1017-1031.e14

Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption

Chikina AS, Nadalin F, Maurin M, San-Roman M, Thomas-Bonafos T, Li XV, Lameiras S, Baulande S, Henri S, Malissen B, Lacerda Mariano L, Barbazan J, Blander JM, Iliev ID, Matic Vignjevic D, Lennon-Duménil AM 2020 Oct Cell 183 411-428.e16

Gut Mycobiota in Immunity and Inflammatory Disease

Li XV, Leonardi I, Iliev ID 2019 Jun Immunity 50 1365-1379

Response to Fungal Dysbiosis by Gut-Resident CX3CR1 + Mononuclear Phagocytes Aggravates Allergic Airway Disease

Li X, Leonardi I, Semon A, Doron I, Gao IH, Putzel GG, Kim Y, Kabata H, Artis D, Fiers WD, Ramer-Tait AE, Iliev ID 2018 Dec Cell Host and Microbe 24 847-856.e4

Macrophage interactions with fungi and bacteria in inflammatory bowel disease

Leonardi I, Li X, Iliev ID 2018 Nov Current Opinion in Gastroenterology 34 392-397

CX3CR1+, mononuclear phagocytes control immunity to intestinal fungi

Leonardi I, Li X, Semon A, Li D, Doron I, Putzel G, Bar A, Prieto D, Rescigno M, McGovern DP, Pla J, Iliev ID 2018 Jan Science 359 232-236

Candidalysin sets off the innate alarm

Li X, Leonardi I, Iliev ID 2017 Science Immunology 2

Tpl2 promotes innate cell recruitment and effector T cell differentiation to limit Citrobacter rodentium burden and dissemination

Acuff NV, Li X, Latha K, Nagy T, Watford WT 2017 Infection and immunity 85

Tpl2 promotes neutrophil trafficking, oxidative burst, and bacterial killing

Acuff NV, Li X, Elmore J, Rada B, Watford WT 2017 Journal of Leukocyte Biology 101 1325-1333

Tumor progression locus 2 (Tpl2) activates the mammalian Target of Rapamycin (mTOR) pathway, inhibits Forkhead Box P3 (FoxP3) expression, and limits regulatory T cell (Treg) immunosuppressive functions

Li X, Acuff NV, Peeks AR, Kirkland R, Wyatt KD, Nagy T, Watford WT 2016 Aug Journal of Biological Chemistry 291 16802-16815

Tumor progression locus 2 differentially regulates IFNγ and IL-17 production by effector CD4+ T cells in a T cell transfer model of colitis

Acuff NV, Li X, Kirkland R, Nagy T, Watford WT 2015 Mar PloS one 10