Publications

  1. Bann GG, Dos Santos M, Chen K, Tan W, Bezprozvannaya S, Gan P, Xu L, Liu N, Bassel-Duby R, Olson EN. Cellular Reprogramming by PHF7 Enhances Cardiac Function Following Myocardial Infarction. Circulation. 2025 Sep 2 (Epub Jul 9, 2025). doi: 10.1161/CIRCULATIONAHA.124.072733 Circulation
  2. Vainshtein A, Blaauw B, De Bock K, Munoz-Canoves P, Olson EN, Ottenheijm CAC, Richter EA, Ruas JL, Schaffer L, Spiegelman B, et al. The Hallmarks of Skeletal Muscle Health. Nature Metabolism. 2026 Aug 20. doi: 10.1038/s42255-026-01595-9 Nature Metabolism
  3. Gan P, Zhou X, Shah AM, Bezprozvannaya S, Chen K, Ding Q, Li H, Xu L, Liu N, Olson EN. Engineering a Serum Response Factor Superactivator of Smooth Muscle Gene Expression with a Condensate-Forming Domain. Proceedings of the National Academy of Sciences. 2025 Sep 23. doi: 10.1073/pnas.2514363122 PNAS
  4. Durbacz MZ, Zhang Y, Li H, Nishiyama T, Sanchez-Ortiz E, McAnally JR, Alzhanov D, Liu N, Olson EN. Optimized Genomic Editing of a Common Duchenne Muscular Dystrophy Mutation in Patient-Derived Muscle Cells and a New Humanized Mouse Model. Molecular Therapy: Nucleic Acids. 2025 Jun;36:102569. doi: 10.1016/j.omtn.2025.102569 Open Access
  5. Kankanamge LP, An H, Guo Q, Prondzynski M, Kwon SH, Bonde DA, Pu WT, Olson EN, Cui M. Nrf1 Coordinates Proteasome Activity and Autophagy to Maintain Cardiac Proteostasis. Communications Biology. 2026 Apr 17. doi: 10.1038/s42003-026-10067-5 Commun. Biology

All Publications by Year

For a complete bibliography, visit Dr. Olson's Google Scholar profile (h-index 256, 228,000+ citations) or ORCID 0000-0003-1151-8262.

2026

  • Vainshtein A, Blaauw B, De Bock K, Munoz-Canoves P, Olson EN, Ottenheijm CAC, Richter EA, Ruas JL, Schaffer L, Spiegelman B, et al. The Hallmarks of Skeletal Muscle Health. Nature Metabolism. 2026 Aug 20. doi: 10.1038/s42255-026-01595-9
  • Kankanamge LP, An H, Guo Q, Prondzynski M, Kwon SH, Bonde DA, Pu WT, Olson EN, Cui M. Nrf1 Coordinates Proteasome Activity and Autophagy to Maintain Cardiac Proteostasis. Communications Biology. 2026 Apr 17. doi: 10.1038/s42003-026-10067-5

2025

  • Gan P, Zhou X, Shah AM, Bezprozvannaya S, Chen K, Ding Q, Li H, Xu L, Liu N, Olson EN. Engineering a Serum Response Factor Superactivator of Smooth Muscle Gene Expression with a Condensate-Forming Domain. Proceedings of the National Academy of Sciences. 2025 Sep 23. doi: 10.1073/pnas.2514363122
  • Bann GG, Dos Santos M, Chen K, Tan W, Bezprozvannaya S, Gan P, Xu L, Liu N, Bassel-Duby R, Olson EN. Cellular Reprogramming by PHF7 Enhances Cardiac Function Following Myocardial Infarction. Circulation. 2025 Sep 2 (Epub Jul 9, 2025). doi: 10.1161/CIRCULATIONAHA.124.072733
  • Dos Santos M, Bezprozvannaya S, McAnally JR, Cai C, Liu N, Olson EN. A Mechanistic Basis of Fast Myofiber Vulnerability to Neuromuscular Diseases. Cell Reports. 2025 Jul. doi: 10.1016/j.celrep.2025.115959
  • Durbacz MZ, Zhang Y, Li H, Nishiyama T, Sanchez-Ortiz E, McAnally JR, Alzhanov D, Liu N, Olson EN. Optimized Genomic Editing of a Common Duchenne Muscular Dystrophy Mutation in Patient-Derived Muscle Cells and a New Humanized Mouse Model. Molecular Therapy: Nucleic Acids. 2025 Jun;36:102569. doi: 10.1016/j.omtn.2025.102569

2024

  • Zhang Y, Dos Santos M, Huang H, Chen K, Iyengar P, Infante R, Polanco PM, Brekken RA, Cai C, Caijgas A, Cano Hernandez K, Xu L, Bassel-Duby R, Liu N, Olson EN. A Molecular Pathway for Cancer Cachexia-Induced Muscle Atrophy Revealed at Single-Nucleus Resolution. Cell Reports. 2024 Aug 27;43(8):114587. doi: 10.1016/j.celrep.2024.114587
  • Olson EN. Myocardial Regeneration: Feasible or Fantasy? Circulation. 2024 Jul 30;150(5):347–349. doi: 10.1161/CIRCULATIONAHA.124.070136
  • Vargas Aguilar S, Cui M, Tan W, Sanchez-Ortiz E, Bassel-Duby R, Liu N, Olson EN. The PD-1–PD-L1 Pathway Maintains an Immunosuppressive Environment Essential for Neonatal Heart Regeneration. Nature Cardiovascular Research. 2024 Mar 1;3(3):389–402. doi: 10.1038/s44161-024-00447-7
  • Gan P, Eppert M, De La Cruz N, Lyons H, Shah AM, Veettil RT, Chen K, Pradhan P, Bezprozvannaya S, Xu L, Liu N, Olson EN, Sabari BR. Coactivator Condensation Drives Cardiovascular Cell Lineage Specification. Science Advances. 2024 Mar 10;10(11):eadk7160. doi: 10.1126/sciadv.eadk7160

2023

  • Lebek S, Chemello F, Caravia XM, Tan W, Li H, Chen K, Xu L, Liu N, Bassel-Duby R, Olson EN. Ablation of CaMKIIδ Oxidation by CRISPR-Cas9 Base Editing as a Therapy for Cardiac Disease. Science. 2023 Jan 13;379(6628):179–185. doi: 10.1126/science.ade1105
  • Chai AC, Cui M, Chemello F, Li H, Chen K, Tan W, Atmanli A, McAnally JR, Zhang Y, Xu L, Liu N, Bassel-Duby R, Olson EN. Base Editing Correction of Hypertrophic Cardiomyopathy in Human Cardiomyocytes and Humanized Mice. Nature Medicine. 2023 Feb;29(2):401–411. doi: 10.1038/s41591-022-02176-5
  • Long T, Zhang Y, Donnelly L, Li H, Pien YC, Liu N, Olson EN, Li X. Cryo-EM Structures of Myomaker Reveal a Molecular Basis for Myoblast Fusion. Nature Structural and Molecular Biology. 2023 Nov;30(11):1746–1754. doi: 10.1038/s41594-023-01110-8
  • Dos Santos M, Shah AM, Zhang Y, Bezprozvannaya S, Chen K, Xu L, Lin W, McAnally JR, Bassel-Duby R, Liu N, Olson EN. Opposing Gene Regulatory Programs Governing Myofiber Development and Maturation Revealed at Single Nucleus Resolution. Nature Communications. 2023 Jul 19;14(1):4333. doi: 10.1038/s41467-023-40073-8
  • Zhang Y, Ramirez-Martinez A, Chen K, McAnally JR, Cai C, Durbacz MZ, Chemello F, Wang Z, Xu L, Bassel-Duby R, Liu N, Olson EN. Net39 Protects Muscle Nuclei from Mechanical Stress during the Pathogenesis of Emery-Dreifuss Muscular Dystrophy. Journal of Clinical Investigation. 2023 Jul 3;133(13):e163333. doi: 10.1172/JCI163333
  • Shah AM, Guo L, Morales MG, Jaichander P, Chen K, Huang H, Cano Hernandez K, Xu L, Bassel-Duby R, Olson EN, Liu N. TWIST2-Mediated Chromatin Remodeling Promotes Fusion-Negative Rhabdomyosarcoma. Science Advances. 2023 Apr 28;9(17):eade8184. doi: 10.1126/sciadv.ade8184
  • Chai AC, Chemello F, Li H, Nishiyama T, Chen K, Zhang Y, Sánchez-Ortiz E, Alomar A, Xu L, Liu N, Bassel-Duby R, Olson EN. Single-Swap Editing for the Correction of Common Duchenne Muscular Dystrophy Mutations. Molecular Therapy: Nucleic Acids. 2023;32:522–535. doi: 10.1016/j.omtn.2023.04.009
  • Garry GA, Olson EN. Reprogramming of Cardiac Cell Fate as a Therapeutic Strategy for Ischemic Heart Disease. Journal of Molecular and Cellular Cardiology. 2023 Jun;179:2–6. doi: 10.1016/j.yjmcc.2023.03.013
  • Cui M, Bezprozvannaya S, Hao T, Elnwasany A, Szweda LI, Liu N, Bassel-Duby R, Olson EN. Transcription Factor NFYa Controls Cardiomyocyte Metabolism and Proliferation during Mouse Fetal Heart Development. Developmental Cell. 2023 Dec 18;58(24):2867–2880. doi: 10.1016/j.devcel.2023.10.012

2022

  • Nishiyama T, Zhang Y, Cui M, Li H, Sanchez-Ortiz E, McAnally JR, Tan W, Kim J, Chen K, Xu L, Bassel-Duby R, Olson EN. Precise Genomic Editing of Pathogenic Mutations in RBM20 Rescues Dilated Cardiomyopathy. Science Translational Medicine. 2022 Nov 23;14(672):eade1633. doi: 10.1126/scitranslmed.ade1633