Publications for Lorena Saelices, Ph.D.

Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis.

Circulating transthyretin and retinol binding protein 4 levels among middle-age V122I TTR carriers in the general population.

Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.

Author Correction: O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology.

O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology.

O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology.

Disease-associated patterns of acetylation stabilize tau fibril formation.

Disease-associated patterns of acetylation stabilize tau fibril formation.

Conformational inhibitors of protein aggregation.

Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.

Update on Disease-Specific Biomarkers in Transthyretin Cardiac Amyloidosis.

Structural polymorphism of amyloid fibrils in cardiac ATTR amyloidosis revealed by cryo-electron microscopy

Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores.

General model for estimation of indoor radon concentration dynamics.

Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.

The inhibition of cellular toxicity of amyloid-beta by dissociated transthyretin.

A pair of peptides inhibits seeding of the hormone transporter transthyretin into amyloid fibrils.

Testing and Calibration of CDs as Radon Detectors at Highly Variable Radon Concentrations and Temperatures.

Assessment of the effects of transthyretin peptide inhibitors in Drosophila models of neuropathic ATTR.

Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition.

Crystal structures of amyloidogenic segments of human transthyretin.

Common fibrillar spines of amyloid-? and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors.

Improvement of the Uranium Sequestration Ability of a Chlamydomonas sp. (ChlSP Strain) Isolated From Extreme Uranium Mine Tailings Through Selection for Potential Bioremediation Application.

Dissecting the Binding between Glutamine Synthetase and Its Two Natively Unfolded Protein Inhibitors.

Uncovering the Mechanism of Aggregation of Human Transthyretin.

A core of three amino acids at the carboxyl-terminal region of glutamine synthetase defines its regulation in cyanobacteria.

Kaolin and copper-based products applications: ecotoxicology on four natural enemies.

Intercomparison exercise on external gamma dose rate under field conditions at the laboratory of natural radiation (Saelices el Chico, Spain).

The inactivating factor of glutamine synthetase IF17 is an intrinsically disordered protein, which folds upon binding to its target.

Mutational analysis of the inactivating factors, IF7 and IF17 from Synechocystis sp. PCC 6803: critical role of arginine amino acid residues for glutamine synthetase inactivation.

Posttranscriptional regulation of glutamine synthetase in the filamentous Cyanobacterium Anabaena sp. PCC 7120: differential expression between vegetative cells and heterocysts.

Identification of the gene responsible for torulene cleavage in the Neurospora carotenoid pathway.

Radon exposure in uranium mining industry vs. exposure in tourist caves.