Publications

The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries.

Mitchell PS, Sandstrom A, Vance RE, 2019 10 Curr Opin Immunol 60 37-45

Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes.

Sandstrom A, Mitchell PS, Goers L, Mu EW, Lesser CF, Vance RE, 2019 04 Science 6435 364

Molecular characterization of a fungal gasdermin-like protein.

Daskalov A, Mitchell PS, Sandstrom A, Vance RE, Glass NL, 2020 08 Proc Natl Acad Sci U S A 31 117 18600-18607

Sandstrom A, Vance RE, 2018 03 J Exp Med 3 215 723-724

The CD3 conformational change in the ?d T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing.

Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WWA, 2014 Jun Cell Rep 5 7 1704-1715

The intracellular B30.2 domain of butyrophilin 3A1 binds phosphoantigens to mediate activation of human V?9Vd2 T cells.

Sandstrom A, Peigné CM, Léger A, Crooks JE, Konczak F, Gesnel MC, Breathnach R, Bonneville M, Scotet E, Adams EJ, 2014 Apr Immunity 4 40 490-500

The molecular basis for modulation of human V?9Vd2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies.

Palakodeti A, Sandstrom A, Sundaresan L, Harly C, Nedellec S, Olive D, Scotet E, Bonneville M, Adams EJ, 2012 Sep J Biol Chem 39 287 32780-90

?d T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion.

Sandstrom A, Scharf L, McRae G, Hawk AJ, Meredith SC, Adams EJ, 2012 Feb J Biol Chem 8 287 6035-43

Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.

Rizk SS, Paduch M, Heithaus JH, Duguid EM, Sandstrom A, Kossiakoff AA, 2011 Apr Nat Struct Mol Biol 4 18 437-42

Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance.

Ho JD, Yeh R, Sandstrom A, Chorny I, Harries WE, Robbins RA, Miercke LJ, Stroud RM, 2009 May Proc Natl Acad Sci U S A 18 106 7437-42

Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity.

Wurfel MM, Park WY, Radella F, Ruzinski J, Sandstrom A, Strout J, Bumgarner RE, Martin TR, 2005 Aug J Immunol 4 175 2570-8