Publications

Glycerol as a precursor for hepatic de novo glutathione synthesis in human liver.

Jin ES, Malloy CR, Sharma G, Finn E, Fuller KNZ, Reyes YG, Lovell MA, Derderian SC, Schoen JA, Inge TH, Cree MG, 2023 Jul Redox Biol 63 102749

Oxidation of hyperpolarized [1-13 C]pyruvate in isolated rat kidneys.

Sharma G, Maptue N, Rahim M, Mijes MLT, Hever T, Wen X, Funk AM, Malloy CR, Young JD, Khemtong C, 2022 Oct NMR Biomed e4857

Co-Polarized [1-13C]Pyruvate and [1,3-13C2]Acetoacetate Provide a Simultaneous View of Cytosolic and Mitochondrial Redox in a Single Experiment.

Sharma G, Wen X, Maptue NR, Hever T, Malloy CR, Sherry AD, Khemtong C, 2021 11 ACS Sens 11 6 3967-3977

PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart.

Li Q, Li C, Elnwasany A, Sharma G, An YA, Zhang G, Elhelaly WM, Lin J, Gong Y, Chen G, Wang M, Zhao S, Dai C, Smart CD, Liu J, Luo X, Deng Y, Tan L, Lv SJ, Davidson SM, Locasale JW, Lorenzi PL, Malloy CR, Gillette TG, Vander Heiden MG, Scherer PE, Szweda LI, Fu G, Wang ZV, 2021 08 Circulation 9 144 712-727

Real-time hyperpolarized 13C magnetic resonance detects increased pyruvate oxidation in pyruvate dehydrogenase kinase 2/4-double knockout mouse livers.

Sharma G, Wu CY, Wynn RM, Gui W, Malloy CR, Sherry AD, Chuang DT, Khemtong C, 2019 Nov Sci Rep 1 9 16480

Metabolism of hyperpolarized 13 C-acetoacetate to ?-hydroxybutyrate detects real-time mitochondrial redox state and dysfunction in heart tissue.

Chen W, Sharma G, Jiang W, Maptue NR, Malloy CR, Sherry AD, Khemtong C, 2019 Apr NMR Biomed e4091

MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid ?-Oxidation.

Makarewich CA, Baskin KK, Munir AZ, Bezprozvannaya S, Sharma G, Khemtong C, Shah AM, McAnally JR, Malloy CR, Szweda LI, Bassel-Duby R, Olson EN 2018 Jun Cell Rep 13 23 3701-3709

Recent Advances Associated with Cardiometabolic Remodeling in Diabetes-induced Heart Failure.

Sharma G, Chaurasia SS, Carlson MA, Mishra PK, 2024 Oct Am J Physiol Heart Circ Physiol

iPhone or Blackberry? The unsure future of Ex-Vivo Lung Perfusion: A Commentary on Ex-Vivo Lung Perfusion National Trends and Post-Transplant Outcomes.

Sharma G, Jessen ME, Peltz M, 2024 Oct J Heart Lung Transplant

Analyses of mitochondrial metabolism in diseases: a review on 13C magnetic resonance tracers.

Sharma G, Duarte S, Shen Q, Khemtong C, 2024 Nov RSC Adv 51 14 37871-37885

Enhancing Cancer Diagnosis with Real-Time Feedback: Tumor Metabolism through Hyperpolarized 1-13C Pyruvate MRSI.

Sharma G, Enriquez JS, Armijo R, Wang M, Bhattacharya P, Pudakalakatti S, 2023 Apr Metabolites 5 13

Aflatoxin B1 Toxicity and Protective Effects of Curcumin: Molecular Mechanisms and Clinical Implications.

Dai C, Tian E, Hao Z, Tang S, Wang Z, Sharma G, Jiang H, Shen J, 2022 Oct Antioxidants (Basel) 10 11

Quercetin Attenuates Quinocetone-Induced Cell Apoptosis In Vitro by Activating the P38/Nrf2/HO-1 Pathway and Inhibiting the ROS/Mitochondrial Apoptotic Pathway.

Dai C, Zhang Q, Shen L, Sharma G, Jiang H, Wang Z, Shen J, 2022 Jul Antioxidants (Basel) 8 11

13C-Labeled Diethyl Ketoglutarate Derivatives as Hyperpolarized Probes of 2-Ketoglutarate Dehydrogenase Activity.

Singh J, Suh EH, Sharma G, Chen J, Hackett EP, Wen X, Sherry AD, Khemtong C, Malloy CR, Park JM, Kovacs Z, 2021 Nov Anal Sens 4 1 156-160

Imaging ?-Cell Function Using a Zinc-Responsive MRI Contrast Agent May Identify First Responder Islets.

Thapa B, Suh EH, Parrott D, Khalighinejad P, Sharma G, Chirayil S, Sherry AD, 2021 Front Endocrinol (Lausanne) 12 809867

Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress.

Dai C, Li Q, May HI, Li C, Zhang G, Sharma G, Sherry AD, Malloy CR, Khemtong C, Zhang Y, Deng Y, Gillette TG, Xu J, Scadden DT, Wang ZV, 2020 Sep Cell Rep 9 32 108087

Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression.

Cardoso AC, Lam NT, Savla JJ, Nakada Y, Pereira AHM, Elnwasany A, Menendez-Montes I, Ensley EL, Petric UB, Sharma G, Sherry AD, Malloy CR, Khemtong C, Kinter MT, Tan WLW, Anene-Nzelu CG, Foo RS, Nguyen NUN, Li S, Ahmed MS, Elhelaly WM, Abdisalaam S, Asaithamby A, Xing C, Kanchwala M, Vale G, Eckert KM, Mitsche MA, McDonald JG, Hill JA, Huang L, Shaul PW, Szweda LI, Sadek HA, 2020 Feb Nat Metab 2 2 167-178

Molecular Insights of Copper Sulfate Exposure-Induced Nephrotoxicity: Involvement of Oxidative and Endoplasmic Reticulum Stress Pathways.

Dai C, Liu Q, Li D, Sharma G, Xiong J, Xiao X, 2020 07 Biomolecules 7 10

A Comprehensive Toxicological Assessment of Fulvic Acid.

Dai C, Xiao X, Yuan Y, Sharma G, Tang S, 2020 Evid Based Complement Alternat Med 2020 8899244

Probing carbohydrate metabolism using hyperpolarized 13 C-labeled molecules.

Singh J, Suh EH, Sharma G, Khemtong C, Sherry AD, Kovacs Z, 2018 Nov NMR Biomed e4018

C-Enriched Carbon Dioxide in Tissues for Measuring pH.

Maptue N, Jiang W, Harrison C, Funk AM, Sharma G, Malloy CR, Sherry D, Khemtong C 2018 Nov ACS Sens 11 3 2232-2236

Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice.

Wu CY, Tso SC, Chuang JL, Gui WJ, Lou M, Sharma G, Khemtong C, Qi X, Wynn RM, Chuang DT 2018 Mar Mol Metab

A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity.

Wu CY, Satapati S, Gui W, Wynn RM, Sharma G, Lou M, Qi X, Burgess SC, Malloy C, Khemtong C, Sherry AD, Chuang DT, Merritt ME 2018 Jun J. Biol. Chem. 25 293 9604-9613

Role of Moringa oleifera in regulation of diabetes-induced oxidative stress.

Jaiswal D, Rai PK, Mehta S, Chatterji S, Shukla S, Rai DK, Sharma G, Sharma B, Khair S, Watal G, 2013 Jun Asian Pac J Trop Med 6 6 426-32

Biomedical applications of nano-antioxidant.

Watal G, Watal A, Rai PK, Rai DK, Sharma G, Sharma B, 2013 Methods Mol Biol 1028 147-51