Recent Publications

  • Manouchehri N, Hussain RZ, Cravens PD, Esaulova E, Artyomov MN, Edelson BT, Wu GF, Cross AH, Doelger R, Loof N, Eagar TN, Forsthuber TG, Calvier L, Herz J, Stüve O. CD11c+CD88+CD317+ myeloid cells are critical mediators of persistent
    CNS autoimmunity. Proceedings of the National Academy of Sciences. 20216;118(14):e2014492118.
  • Manouchehri N, Guisso DR, Hussain RZ, Minassian B, Stüve O. The antioxidant MnTBAP does not effectively downregulate
    CD4 expression in T cells in vivo. Journal of Neuroimmunology. 2021;354:577544.
  • Calvier L, Demuth G, Manouchehri N, Sacharidou A, Mineo C, Shaul PW, Monson NL, Kounnas MZ, Stüve O, Herz. Reelin Depletion from Plasma Protects Against Multiple Sclerosis by Decreasing Vascular Permeability. Science Translational Medicine.
    2020;12:eaay7675. doi: 10.1126/scitranslmed.aay7675.
  • Manouchehri N, Hussain RZ, Cravens PD, Doelger R, Greenberg BM, Okuda DT, Forsthuber TG, Eagar TN, Stüve O. Limitations of
    cell-lineage-specific non-dynamic gene recombination in CD11c.Cre+ITGA4fl/fl mice. Journal of Neuroimmunology. 2020;344:577245.
  • Kuhbandner K, Hammer A, Haase S, Terbrack E, Hoffmann A, Schippers A, Wagner N, Hussain RZ, Miller-Little WA, Koh AY, Stoolman JS, Segal BM, Linker RA, Stüve O. MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis. Frontiers in Immunology. 2019;10:903.
  • Hussain RZ, Cravens PC, Miller-Little WA, Doelger R, Granados V, Herndon E, Okuda DT, Eagar TN, Stüve O. α4 integrin-deficiency in CD19+ B cells does not affect EAE disease in a T cell-mediated disease model. Neurology: Neuroimmunology & Neuroinflammation. 2019;6:e563.
  • Hussain RZ, Cravens PC, Doelger R, Dentel B, Herndon E, Loof N, Tsai P, Okuda DT, Racke MK, Stüve O. TLR3 agonism re-establishes CNS immune competence during α4-integrin deficiency. Annals of Clinical and Translational Neurology. 2018;5:1543-1561.
  • Hussain RZ, Miller-Little WA, Doelger R, Cutter G, Loof N, Cravens PD, Stüve O. Defining standard enzymatic dissociation methods for individual brains and spinal cords in EAE. Neurology: Neuroimmunology & Neuroinflammation. 2018;5:e437.
  • Hussain RZ, Miller-Little WA, Lambracht-Washington D, Jaramillo TC, Takahashi M, Zhang S, Fu M, Cutter GR, Hayardeny L, Powell CM, Rosenberg RN, Stüve O. Laquinimod has no effects on brain volume or cellular CNS composition in the F1 3xTg-AD/C3H mouse model of Alzheimer’s disease. Journal of Neuroimmunology. 2017;309:100-110.
  • Cravens PD, Hussain RZ, Miller-Little WA, Ben L-H, Segal BM, Herndon E, Stüve O. IL-12/IL-23p40 is highly expressed in secondary lymphoid organs and the CNS during all stages of EAE, but its deletion does not affect disease perpetuation. PLoS One. 2016;11(10):e0165248.
  • Arellano B, Hussain RZ, Miller-Little WA, Herndon E, Lambracht-Washington D, Eagar TN, Lewis R, Healey D, Vernino S, Greenberg BM, Stüve O. A single amino acid substitution prevents recognition of a dominant human aquaporin-4 determinant in the context of HLA-DRB1*03:01 by a murine TCR. PLoS One. 2016;11(4):e0152720.