The Kelesidis Lab studies the cross between viral infections and mechanisms of associated end organ damage with a goal to develop novel therapeutic treatments. 

Our lab uses tractable model viruses to learn about niche-specific factors that influence viral infection and evolution.

The overarching goals of our lab are to understand the posttranscriptional mechanisms of gene expression and regulation in the Kaposi's sarcoma-associated herpesvirus (KSHV) and its human host cell. We are particularly focused on the mechanisms and regulation of nuclear RNA stability, polyadenylation, and mRNA processing by viral and by host cell factors.