The lab's long-term goal is to illuminate the function of immune surface molecules and to open up a new research field at the interface of cancer, immunology, and stem cell research. Zhang Lab also actively develops novel therapies for cancer treatment.

Chen lab studies how dysregulation of RNA synthesis and degradation drives childhood cancers with the ultimate goal of identifying new therapeutic vulnerabilities to exploit in treating them.

Castrillion Lab's work is aimed at understanding why endometrial or uterine cancers arise and spread, with an eye on prevention, earlier and more accurate diagnosis, improved treatments, and better overall patient outcomes.