Publications

A Multi-Color Immunofluorescence Assay to Distinguish Intracellular From External Leishmania Parasites

Datta A, Barrie U, Wetzel DM, 2024 Jun Bio-protocol

Cutaneous Leishmania mexicana infections in the United States: defining strains through endemic human pediatric cases in northern Texas.

Nepal B, McCormick-Baw C, Patel K, Firmani S, Wetzel DM, 2024 Feb mSphere

MAPK/ERK Activation in Macrophages Promotes Leishmania Internalization and Pathogenesis

Umaru Barrie, Katherine Floyd, Arani Datta, Dawn M. Wetzel 2024 May Microbes and Infection

Leishmania in Texas: A Contemporary One Health Scoping Review of Vectors, Reservoirs, and Human Health

Jibowu MH, Chung R, Tang NL, Guo S, Lawton LA, Sullivan BJ, Wetzel DM, Gunter SM 2025 Aug Biology 14

Tubulin detyrosination shapes Leishmania cytoskeletal architecture and virulence

Corrales RM, Vincent J, Crobu L, Neish R, Nepal B, Espeut J, Pasquier G, Gillard G, Cazevieille C, Mottram JC, Wetzel DM, Sterkers Y, Rogowski K, Lévêque MF 2025 Jan Proceedings of the National Academy of Sciences of the United States of America 122

Toxoplasma replication is inhibited by MMV676477 without development of resistance

Abbaali I, Truong D, Wetzel DM, Morrissette NS 2025 Jan Cytoskeleton 82 5-11

Using machine learning to dissect host kinases required for Leishmania internalization and development

Wei L, Barrie U, Aloisio GM, Khuong FT, Arang N, Datta A, Kaushansky A, Wetzel DM 2024 Dec Molecular and Biochemical Parasitology 260

Synthesis of the 5/5-spiroindimicin alkaloids: development of a general synthetic approach and biological investigations

Banerjee A, Brisco TA, Ray S, Datta A, Zhang X, Zhang Z, Busse AA, Niederstrasser H, Sumida K, Posner BA, Wetzel DM, Phillips MA, Smith MW 2024 Oct Organic and Biomolecular Chemistry 22 9413-9425

MAPK/ERK activation in macrophages promotes Leishmania internalization and pathogenesis

Barrie U, Floyd K, Datta A, Wetzel DM 2024 Jul Microbes and Infection 26

A Multi-Color Immunofluorescence Assay to Distinguish Intracellular from External Leishmania Parasites

Datta A, Barrie U, Wetzel DM 2024 Jun Bio-protocol 14

Cutaneous Leishmania mexicana infections in the United States: definingstrains through endemic human pediatric cases in northern Texas

Nepal B, McCormick-Baw C, Patel K, Firmani S, Wetzel DM 2024 Mar mSphere 9

Src- and Abl-family kinases activate spleen tyrosine kinase to maximize phagocytosis and Leishmania infection

Ullah I, Barrie U, Kernen RM, Mamula ET, Tho Huu Khuong F, Booshehri LM, Rhodes EL, Bradford JM, Datta A, Wetzel DM 2023 Jul Journal of cell science 136

CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT

Mohamed MF, Gupta K, Goldufsky JW, Roy R, Callaghan LT, Wetzel DM, Kuzel TM, Reiser J, Shafikhani SH 2022 Dec Nature communications 13

Potency and Preclinical Evidence of Synergy of Oral Azole Drugs and Miltefosine in an Ex Vivo Model of Leishmania (Viannia) panamensis Infection

Fernández OL, Rosales-Chilama M, Quintero N, Travi BL, Wetzel DM, Gómez MA, Saravia NG 2022 Jan Antimicrobial agents and chemotherapy 66

Total synthesis of (+)-spiroindimicin A and congeners unveils their antiparasitic activity

Zhang Z, Ray S, Imlay L, Callaghan LT, Niederstrasser H, Mallipeddi PL, Posner BA, Wetzel DM, Phillips MA, Smith MW 2021 Aug Chemical Science 12 10388-10394

An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization

Ullah I, Gahalawat S, Booshehri LM, Niederstrasser H, Majumdar S, Leija C, Bradford JM, Hu B, Ready JM, Wetzel DM 2020 Aug ACS infectious diseases 6 2057-2072

The relative rate of kill of the MMV Malaria Box compounds provides links to the mode of antimalarial action and highlights scaffolds of medicinal chemistry interest

Ullah I, Sharma R, Mete A, Biagini GA, Wetzel DM, Horrocks PD 2020 Feb Journal of Antimicrobial Chemotherapy 75 362-370

Erratum: An outbreak of brucellosis: An adult and pediatric case series (Open Forum Infectious Diseases (2019) 6: 10 (ofz384) DOI: 10.1093/ofid/ofz384)

Hassouneh L, Quadri S, Reto PP, Chaisavaneeyakorn S, Cutrell JB, Wetzel DM, Nijhawan AE 2019 Dec Open Forum Infectious Diseases 6

An Outbreak of Brucellosis: An Adult and Pediatric Case Series

Hassouneh L, Quadri S, Reto PP, Chaisavaneeyakorn S, Cutrell JB, Wetzel DM, Nijhawan AE 2019 Oct Open Forum Infectious Diseases 6

The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education

Ganesan S, Luu TT, Chambers BJ, Meinke S, Brodin P, Vivier E, Wetzel DM, Koleske AJ, Kadri N, Höglund P 2017 Sep Scandinavian Journal of Immunology 86 135-142

The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection

Wetzel DM, Rhodes EL, Li S, McMahon-Pratt D, Koleske AJ 2016 Journal of cell science 129 3130-3143

The Abl and Arg Kinases Mediate Distinct Modes of Phagocytosis and Are Required for Maximal Leishmania Infection

Wetzel DM, McMahon-Pratt D, Koleske AJ 2012 Aug Molecular and cellular biology 32 3176-3186

Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A

Martin FJ, Gomez MI, Wetzel DM, Memmi G, O'Seaghdha M, Soong G, Schindler C, Prince A 2009 Jul Journal of Clinical Investigation 119 1931-1939

Gliding motility leads to active cellular invasion by Cryptosporidium parvum sporozoites

Wetzel DM, Schmidt J, Kuhlenschmidt MS, Dubey JP, Sibley LD 2005 Sep Infection and immunity 73 5379-5387

Evidence that the cADPR signalling pathway controls calcium-mediated microneme secretion in Toxoplasma gondii

Chini EN, Nagamune K, Wetzel DM, Sibley LD 2005 Jul Biochemical Journal 389 269-277

Calcium-mediated protein secretion potentiates motility in Toxoplasma gondii

Wetzel DM, Chen LA, Ruiz FA, Moreno SN, Sibley LD 2004 Nov Journal of cell science 117 5739-5748

Actin filament polymerization regulates gliding motility by apicomplexan parasites

Wetzel DM, Håkansson S, Hu K, Roos D, Sibley LD 2003 Feb Molecular Biology of the Cell 14 396-406

Role of dynactin in endocytic traffic: Effects of dynamitin overexpression and colocalization with CLIP-170

Valetti C, Wetzel DM, Schrader M, Hasbani MJ, Gill SR, Kreis TE, Schroer TA 1999 Dec Molecular Biology of the Cell 10 4107-4120

Dynactin and cytoplasmic dynein-based motility

Bineham JB, Duiardin AD, Gill SR, Ouintvne N, Valelti C, Wetzel D, Demey AJ, Kreis T, Schroer TA 1997 FASEB Journal 11 A1297