Unique genetically-engineered strains generated in the Castrillon laboratory and accepted into the Jackson Laboratory repository as high-impact alleles for widespread distribution to academic investigators are listed below. Please follow the links to the Jackson Laboratory Website for additional information, potential uses, and genotyping protocols:
LSL-PoleP286R a.k.a. B6.12956-Poletm1Dcas/J
BAC-Sprr2f-Cre a.k.a. B6(FVB)-Tg(Sprr2f-cre)2Dcas/J
Vasa-Cre a.k.a. FVB-Tg(Ddx4-cre)1Dcas/J
Vasa-CreERT2 a.k.a. FVB/N-Tg(Ddx4-cre/ERT2)1Das/J
![Genetic tools - carcinosarcoma and Fbxw7 graphics](/sites/default/files/styles/coh_medium/public/2022-11/genetic-tools.png?itok=-B3P3L3a)