Protein Kinase Regulation in Biology and Disease
We investigate the functions and regulation of protein kinases in cellular signaling, and their relation to human disease.
The members of the Cobb lab study the signal-transduction mechanisms and structure-function relationships of protein kinases, and how these relate to cell biological outcomes.
We are particularly focused on:
- ERK MAP kinases
- WNK kinases
- TAO kinases
- NRBP pseudokinases
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