Kinase Regulation and Biology
We investigate how these kinases work in normal biology and are usurped in human disease
The members of the Cobb lab study the signal-transduction mechanisms of protein kinases, and how kinase structures lead to cell biological functions.
We are particularly focused on the contributions of ERK MAP kinases to pancreatic beta cell function and to lung cancers, and on the actions of WNK protein kinases.
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