Farrar Lab

Understanding the signals that regulate immune function.

The Farrar Lab seeks to understand how the immune system sends and receives information that guides its response to infection. We study a variety of external signaling systems ranging from classical cytokines to neurotransmitters. Our goal is to understand how these complex signals integrate to direct immune cell responses to pathogenic organisms.

Dr. David Farrar

Dr. Farrar is a native Texan and a UT Southwestern alumnus. He joined the Department of Immunology here at UT Southwestern in 2001 and continues to train graduate students and post-doctoral fellows interested in immunity.

Dr. Farrer, smiling man with close-cropped hair, beard and mustache, wearing a black shirt, standing in a lab.

Recent News & Discoveries

Flowchart showing the role of adrenergic signaling in regulating circadian rhythms in T cells.

New Funding - July 2023

The Farrar Lab was recently awarded a 5-year NIH grant to study the role of adrenergic signaling in regulating circadian rhythms in T cells.

Flowchart of research

Adrenergic control of gene expression in CD8+ T cells

We discovered that the adrenergic receptor controls important transcriptional pathways in CD8+ T cells as they divide and differentiate in response to viral infection.

On screen behind Drashya: Adrenergic regulation of circadian rhythms in T cell responses to virus infection.

Dr. Drashya Sharma presented her work at Autumn Immunology, 2022

Dr. Drashya Sharma was awarded an Immunology Department travel grant. She attended the 2022 Autumn Immunology Conference in Chicago, where she presented her work on adrenergic entrainment of circadian rhythms in T cells.

Logo on purple background - "Seminars in Immunopathology - Springer" with an sketch of a horses head (or Knight chess piece)

An entire issue devoted to neuroimmune interactions

This issue of "Seminars" highlights recent advances in understanding how the brain controls immune function. Dr. Drashya Sharma co-authored an article in this issue focused on the sympathetic nervous system.

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Current Research Projects

Explore our research topics and read our recent publications.

Research
Scientific flow chart and diagrams