Research Articles
Adrenergic signaling controls early transcriptional programs during CD8+ T cell responses to viral infection.
Estrada LD, Agaç Çobanoglu D, Wise A, Maples RW, Çobanoglu MC, Farrar JD; PLoS One 2022. (PubMed ID: 35944008)
Type I interferon suppresses memory Th2 cell cytokine secretion from allergic subjects.
Chen F, Rowe RK, Gill MA, Farrar JD; Allergy 2019. (PubMed ID: 31541610)
The B2-adrenergic receptor controls inflammation by driving rapid IL-10 secretion.
Agaç D, Estrada LD, Maples R, Hooper LV, Farrar JD; Brain Behav. Immun. 2018. (PubMed ID: 30195028)
Sympathetic neural signaling via the B2-adrenergic receptor suppresses T-cell receptor-mediated human and mouse CD8(+) T-cell effector function.
Estrada LD, Agaç D, Farrar JD; Eur. J. Immunol. 2016. (PubMed ID: 27222010)
Cutting edge: Critical role of glycolysis in human plasmacytoid dendritic cell antiviral responses.
Gagan Bajwa, Ralph J. DeBerardinis, Baomei Shao, Brian Hall, J. David Farrar, Michelle A. Gill; J Immunol 2016. (PubMed ID: 26826244)
STAT4‐mediated transcriptional repression of the IL5 gene in human memory Th2 cells.
Gonzales‐van Horn SR, Estrada LD, van Oers NS, Farrar JD; Eur. J. Immunol. 2016. (PubMed ID: 26990433)
IFN-α suppresses GATA3 transcription from a distal exon and promotes H3K27 trimethylation of the CNS-1 enhancer in human Th2 cells.
Jonathan P. Huber, Sarah R. Gonzales-van Horn, Kole T. Roybal, Michelle A. Gill, J. David Farrar; J Immunol 2014.. (PubMed ID: 24813204)
Pharmacological inhibition of TPL2/MAP3K8 blocks human cytotoxic T lymphocyte effector functions.
Chowdhury, Fatema Z., Leonardo D. Estrada, Sean Murray, James Forman, and J. David Farrar; PloS one 2014. (Pubmed ID: 24642963)
IgE cross-linking critically impairs human monocyte function by blocking phagocytosis.
David M. Pyle, Victoria S. Yang, Rebecca S. Gruchalla, J. David Farrar, Michelle A. Gill; J. Allergy Clin. Immunol. 2013. (Pubmed ID: 23374271)
IL-12 selectively programs effector pathways that are stably expressed in human CD8+ effector memory T cells in vivo.
Fatema Z. Chowdhury, Hilario J. Ramos, Laurie S. Davis, James Forman, J. David Farrar; BLOOD, 2011. (Pubmed ID: 21832277)
Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3.
Jonathan P. Huber, Hilario J. Ramos, Michelle A. Gill, J. David Farrar; J Immunol 2010. (Pubmed ID: 20554961)
Reciprocal responsiveness to interleukin-12 and interferon-α specifies human CD8+ effector versus central memory T-cell fates.
Hilario J. Ramos, Ann M. Davis, Alexander G. Cole, John D. Schatzle, James Forman, J. David Farrar; BLOOD. 2009. (Pubmed ID: 19299334)
Cutting edge: a T-bet-independent role for IFN-α/β in regulating IL-2 secretion in human CD4+ central memory T cells.
Ann M. Davis, Hilario J. Ramos, Laurie S. Davis, J. David Farrar; J Immunol 2008. (Pubmed ID: 19050236)
Blockade of virus infection by human CD4+ T cells via a cytokine relay network.
Ann M. Davis, Kristan A. Hagan, Loderick A. Matthews, Gagan Bajwa, Michelle A. Gill, Michael Gale, J. David Farrar; J Immunol 2008. (Pubmed ID: 18453613)
Reviews
Adrenergic regulation of immune cell function and inflammation.
Sharma D, Farrar JD, Semin Immunopathol 2020. (PubMed ID: 33219396)
Adrenergic Signaling at the Interface of Allergic Asthma and Viral Infections.
Agaç D, Gill MA, Farrar JD Front Immunol 2018. (PubMed ID: 29696025)
Interferon at the crossroads of allergy and viral infections
Sarah R Gonzales-van Horn, J David Farrar, J. Leukoc. Biol. 2015. (PubMed ID: 26026068)
STAT2: A shape-shifting anti-viral super STAT
Chowdhury FZ, Farrar JD. Jak-Stat. 2013. (PubMed ID: 24058798)
Regulation of effector and memory T cell functions by type I interferon
Huber JP, and Farrar JD. Immunology. 2011. (PubMed ID: 21320124)