INTERNAL MEDICINE RESEARCH

Sarah Huen Lab

Are all metabolic changes during inflammation pathologic?

We study how metabolic adaptation promotes survival and tissue protection during sepsis.

Meet the PI

Portrait of Sarah Huen

Sarah Huen, M.D., Ph.D.

Assistant Professor
Principal Investigator
Pharmacology
Internal Medicine-Nephrology

Originally from Chicago, Dr. Huen holds a bachelor's degree in biology from Northwestern University in Evanston, Illinois. She earned her medical degree at Northwestern University Feinberg School of Medicine in Chicago and completed internal medicine residency training at New York University. Intrigued by the pathophysiology of acute kidney injury and frustrated by the lack of any viable therapeutic options, she pursed a research fellowship in nephrology at Yale University, where she also obtained her doctorate in investigative medicine in the laboratory of Lloyd Cantley, M.D., studying the role of macrophages in ischemic kidney injury. She then pursued postdoctoral training with Ruslan Medzhitov, Ph.D., exploring the role of sickness-induced anorexia. The Huen Lab explores the metabolic programs as defense mechanisms in the context of inflammation and tissue injury.

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Kidney section stained blue

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Kidney EM section