New perspectives on tuberculosis
Welcome to our Lab!
For decades, the field of tuberculosis (TB) immunology has focused on T cell mediated protection, yet Mycobacterium tuberculosis (Mtb) still impacts one in four individuals worldwide today. While T cells are clearly important, gaps in this paradigm remain, and a role for the other arm of the immune system – humoral immunity – is less clear.
Our lab focuses on a systems serology approach to show divergent humoral profiles in two classical human states of TB: latent infection (LTB), with no microbiological burden or signs and symptoms of disease yet a T cell signature of infection, and active TB disease (ATB), with the presence of detectable Mtb, signs and symptoms of disease, as well as a T cell signature of infection.
Meet the PI
![Dr. Lenette Lu](/sites/default/files/styles/coh_medium_landscape/public/2022-12/lu-lenette-800x800.jpg?h=fbf7a813&itok=ZPzxV001)
Lenette Lu M.D., Ph.D.
Dr. Lu is a physician-scientist who studies and treats infectious diseases. While her clinical service is centered at Parkland, she spends most of her time in lab with a long-standing interest on the host relationship with microbes.
Get Involved
Meet the Team
Get to know our Principal Investigator and team of researchers.
See Lab Members & Alumni![Lu Lenette Lab Group](/sites/default/files/styles/coh_small_landscape/public/2022-05/lulenette_-mesa-maya-fall-bw.jpeg?h=827069f2&itok=ecEF4jFW)
Join Our Lab
If you're interested in joining our team, please reach out to learn more about open positions.
Explore Opportunities![Lu Lenette Join Our Lab Thumbnail](/sites/default/files/styles/coh_small_landscape/public/2022-05/lulenette_merged.png?h=c2cda508&itok=wauCv__i)
Collaborate with Us
Interested in our research? Get in touch to learn more or find out ways to collaborate.
Get in Touch![Lu Lenette Campus Thumbnail](/sites/default/files/styles/coh_small_landscape/public/2022-03/campus.jpeg?h=307aaf77&itok=Z8fc-o_3)