• Understand how disseminated tumor cells survive in distal organs as residual or latent disease.
  • Define the molecular and metabolic dependencies of metastasis initiating cells.
  • To translate our findings into improved diagnostic and therapeutic modalities for treating residual disease and metastasis.

Research Projects

  • Mechanisms promoting invasion, dissemination, and metastatic competence.
  • Disseminated tumor cells and their ecosystem during metastatic latency. 
  • Mechanisms underlying metastatic dormancy, treatment resistance, and outgrowth of brain metastasis.
  • Metabolic and epigenetic mediators of metastatic latency.