Publications

Identification of roles for H264, H306, H439 and H635 in acid-dependent lipoprotein release by the LDL receptor.

Dong H, Zhao Z, LeBrun DG, Michaely P 2016 Nov J. Lipid Res.

Quantitative fluorescence imaging reveals point of release for lipoproteins during LDLR-dependent uptake.

Pompey S, Zhao Z, Luby-Phelps K, Michaely P 2013 Mar J. Lipid Res. 3 54 744-53

S-nitrosylation of ARH is required for LDL uptake by the LDL receptor.

Zhao Z, Pompey S, Dong H, Weng J, Garuti R, Michaely P 2013 Apr J. Lipid Res.

Cavin-3 dictates the balance between ERK and Akt signaling.

Hernandez VJ, Weng J, Ly P, Pompey S, Dong H, Mishra L, Schwarz M, Anderson RG, Michaely P 2013 Elife 2 e00905

Sterol-dependent nuclear import of ORP1S promotes LXR regulated trans-activation of apoE.

Lee S, Wang PY, Jeong Y, Mangelsdorf DJ, Anderson RG, Michaely P 2012 Oct Exp. Cell Res. 16 318 2128-42

Role of an intramolecular contact on lipoprotein uptake by the LDL receptor.

Zhao Z, Michaely P 2011 Jun Biochim. Biophys. Acta 6 1811 397-408

Localization and structure of the ankyrin-binding site on beta2-spectrin.

Davis L, Abdi K, Machius M, Brautigam C, Tomchick DR, Bennett V, Michaely P 2009 Mar J. Biol. Chem. 11 284 6982-7

The role of calcium in lipoprotein release by the low-density lipoprotein receptor.

Zhao Z, Michaely P 2009 Aug Biochemistry 30 48 7313-24

The epidermal growth factor homology domain of the LDL receptor drives lipoprotein release through an allosteric mechanism involving H190, H562, and H586.

Zhao Z, Michaely P 2008 Sep J. Biol. Chem. 39 283 26528-37

Loss of the transforming growth factor-? effector ?2-Spectrin promotes genomic instability.

Chen J, Shukla V, Farci P, Andricovich J, Jogunoori W, Kwong LN, Katz LH, Shetty K, Rashid A, Su X, White J, Li L, Wang AY, Blechacz B, Raju GS, Davila M, Nguyen BN, Stroehlein JR, Chen J, Kim SS, Levin H, Machida K, Tsukamoto H, Michaely P, Tzatsos A, Mishra B, Amdur R, Mishra L 2017 Feb Hepatology 2 65 678-693

TGF-?/?2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.

Chen J, Yao ZX, Chen JS, Gi YJ, Muñoz NM, Kundra S, Herlong HF, Jeong YS, Goltsov A, Ohshiro K, Mistry NA, Zhang J, Su X, Choufani S, Mitra A, Li S, Mishra B, White J, Rashid A, Wang AY, Javle M, Davila M, Michaely P, Weksberg R, Hofstetter WL, Finegold MJ, Shay JW, Machida K, Tsukamoto H, Mishra L 2016 Feb J. Clin. Invest. 2 126 527-542

Quantitative Fluorescence Co-localization to Study Protein-Receptor Complexes.

Pompey SN, Michaely P, Luby-Phelps K 2013 Methods Mol. Biol. 1008 439-53

Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR.

Michaely P, Zhao Z, Li WP, Garuti R, Huang LJ, Hobbs HH, Cohen JC 2007 Jul EMBO J. 14 26 3273-82

Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia.

Jones C, Garuti R, Michaely P, Li WP, Maeda N, Cohen JC, Herz J, Hobbs HH 2007 Jan J. Clin. Invest. 1 117 165-74

Nanospring behaviour of ankyrin repeats.

Lee G, Abdi K, Jiang Y, Michaely P, Bennett V, Marszalek PE 2006 Mar Nature 7081 440 246-9

Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake.

Yu L, Bharadwaj S, Brown JM, Ma Y, Du W, Davis MA, Michaely P, Liu P, Willingham MC, Rudel LL 2006 Mar J. Biol. Chem. 10 281 6616-24

The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits.

Garuti R, Jones C, Li WP, Michaely P, Herz J, Gerard RD, Cohen JC, Hobbs HH 2005 Dec J. Biol. Chem. 49 280 40996-1004

Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B.

Mohler PJ, Davis JQ, Davis LH, Hoffman JA, Michaely P, Bennett V 2004 Mar J. Biol. Chem. 13 279 12980-7

The modular adaptor protein ARH is required for low density lipoprotein (LDL) binding and internalization but not for LDL receptor clustering in coated pits.

Michaely P, Li WP, Anderson RG, Cohen JC, Hobbs HH 2004 Aug J. Biol. Chem. 32 279 34023-31

ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.

He G, Gupta S, Yi M, Michaely P, Hobbs HH, Cohen JC 2002 Nov J. Biol. Chem. 46 277 44044-9

Crystal structure of a 12 ANK repeat stack from human ankyrinR.

Michaely P, Tomchick DR, Machius M, Anderson RG 2002 Dec EMBO J. 23 21 6387-96

Presence of oxidized cholesterol in caveolae uncouples active platelet-derived growth factor receptors from tyrosine kinase substrates.

Liu P, Wang P, Michaely P, Zhu M, Anderson RG 2000 Oct J. Biol. Chem. 41 275 31648-54

Polarized distribution of endogenous Rac1 and RhoA at the cell surface.

Michaely PA, Mineo C, Ying YS, Anderson RG 1999 Jul J. Biol. Chem. 30 274 21430-6

A requirement for ankyrin binding to clathrin during coated pit budding.

Michaely P, Kamal A, Anderson RG, Bennett V 1999 Dec J. Biol. Chem. 50 274 35908-13

The ANK repeats of erythrocyte ankyrin form two distinct but cooperative binding sites for the erythrocyte anion exchanger.

Michaely P, Bennett V 1995 Sep J. Biol. Chem. 37 270 22050-7

Mechanism for binding site diversity on ankyrin. Comparison of binding sites on ankyrin for neurofascin and the Cl-/HCO3- anion exchanger.

Michaely P, Bennett V 1995 Dec J. Biol. Chem. 52 270 31298-302

The membrane-binding domain of ankyrin contains four independently folded subdomains, each comprised of six ankyrin repeats.

Michaely P, Bennett V 1993 Oct J. Biol. Chem. 30 268 22703-9

The ANK repeat: a ubiquitous motif involved in macromolecular recognition.

Michaely P, Bennett V 1992 May Trends Cell Biol. 5 2 127-9

Feline cytotoxic large granular lymphocytes induced by recombinant human IL-2.

Tompkins MB, Pang VF, Michaely PA, Feinmehl RI, Basgall EJ, Baszler TV, Zachary JF, Tompkins WA 1989 Jul J. Immunol. 2 143 749-54