Translational Pathophysiology

Our work encompasses individual molecules, in vitro cell models, in vivo animal models, and metabolic human studies.

Acute and chronic kidney disease

We study pathophysiologic mechanisms involving mineral metabolism mediating the acute kidney injury, acute kidney injury-to-chronic kidney disease transition, cardiovascular complications of chronic kidney disease.


We also focus on uric acid nephrolithiasis and the metabolic syndrome, renal acidification and citrate handling defects and propensity for calcium stones. 


The Moe Lab is committed to biomedical education with teaching activities for medical students, graduate students, residents, and fellows. 


Our research is driven by questions, not by techniques. We are pleased to collaborate with researchers who bring new perspectives: