Publications

Nox2 Regulates Platelet Activation and NET Formation in the Lung.

Hook JS, Cao M, Potera RM, Alsmadi NZ, Schmidtke DW, Moreland JG, 2019 Front Immunol 10 1472

Alveolar Macrophage Chemokine Secretion Mediates Neutrophilic Lung Injury in Nox2-Deficient Mice.

Potera RM, Cao M, Jordan LF, Hogg RT, Hook JS, Moreland JG 2018 Oct Inflammation

Neutrophil Phenotype Correlates With Postoperative Inflammatory Outcomes in Infants Undergoing Cardiopulmonary Bypass.

Huber JN, Hilkin BM, Hook JS, Brophy PD, Davenport TL, Davis JE, Colaizy TT, Moreland JG 2017 Oct Pediatr Crit Care Med

Correction: Interferon Regulatory Factor 6 Has a Protective Role in the Host Response to Endotoxic Shock.

Joly S, Rhea L, Volk P, Moreland JG, Dunnwald M 2017 PLoS ONE 1 12 e0171459

Neutrophil azurophilic granule exocytosis is primed by TNF-a and partially regulated by NADPH oxidase.

Potera RM, Jensen MJ, Hilkin BM, South GK, Hook JS, Gross EA, Moreland JG 2016 Sep Innate Immun

Craniectomy and Traumatic Brain Injury in Children on Extracorporeal Membrane Oxygenation Support: Case Report and Review of the Literature.

Anton-Martin P, Braga B, Megison S, Journeycake J, Moreland J 2016 Oct Pediatr Emerg Care

A Common Genetic Variant in TLR1 Enhances Human Neutrophil Priming and Impacts Length of Intensive Care Stay in Pediatric Sepsis.

Whitmore LC, Hook JS, Philiph AR, Hilkin BM, Bing X, Ahn C, Wong HR, Ferguson PJ, Moreland JG 2016 Feb J. Immunol. 3 196 1376-86

Interferon Regulatory Factor 6 Has a Protective Role in the Host Response to Endotoxic Shock.

Joly S, Rhea L, Volk P, Moreland JG, Dunnwald M 2016 PLoS ONE 4 11 e0152385

Evaluation of hematologic composition in newborn C57/BL6 mice up to day 35.

White JR, Gong H, Colaizy TT, Moreland JG, Flaherty H, McElroy SJ 2015 Dec Vet Clin Pathol

NOX2 protects against progressive lung injury and multiple organ dysfunction syndrome.

Whitmore LC, Goss KL, Newell EA, Hilkin BM, Hook JS, Moreland JG 2014 May Am. J. Physiol. Lung Cell Mol. Physiol.

ROS-containing endosomal compartments: implications for signaling.

Davis Volk AP, Moreland JG 2014 Meth. Enzymol. 535 201-24

Transepithelial migration of neutrophils into the lung requires TREM-1.

Klesney-Tait J, Keck K, Li X, Gilfillan S, Otero K, Baruah S, Meyerholz DK, Varga SM, Knudson CJ, Moninger TO, Moreland J, Zabner J, Colonna M 2013 Jan J. Clin. Invest. 1 123 138-49

NOX2 Protects against Prolonged Inflammation, Lung Injury, and Mortality following Systemic Insults.

Whitmore LC, Hilkin BM, Goss KL, Wahle EM, Colaizy TT, Boggiatto PM, Varga SM, Miller FJ, Moreland JG 2013 Apr J Innate Immun

Endotoxin priming of neutrophils requires endocytosis and NADPH oxidase-dependent endosomal reactive oxygen species.

Lamb FS, Hook JS, Hilkin BM, Huber JN, Volk AP, Moreland JG 2012 Apr J. Biol. Chem. 15 287 12395-404

Priming of neutrophils and differentiated PLB-985 cells by pathophysiological concentrations of TNF-a is partially oxygen dependent.

Volk AP, Barber BM, Goss KL, Ruff JG, Heise CK, Hook JS, Moreland JG 2011 J Innate Immun 3 3 298-314

Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis.

McCaffrey RL, Schwartz JT, Lindemann SR, Moreland JG, Buchan BW, Jones BD, Allen LA 2010 Oct J. Leukoc. Biol. 4 88 791-805

Activation of swelling-activated chloride current by tumor necrosis factor-alpha requires ClC-3-dependent endosomal reactive oxygen production.

Matsuda JJ, Filali MS, Moreland JG, Miller FJ, Lamb FS 2010 Jul J. Biol. Chem. 30 285 22864-73

Francisella tularensis directly interacts with the endothelium and recruits neutrophils with a blunted inflammatory phenotype.

Moreland JG, Hook JS, Bailey G, Ulland T, Nauseef WM 2009 Jun Am. J. Physiol. Lung Cell Mol. Physiol. 6 296 L1076-84

Electrophysiology of reactive oxygen production in signaling endosomes.

Lamb FS, Moreland JG, Miller FJ 2009 Jun Antioxid. Redox Signal. 6 11 1335-47

ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells.

Drake JM, Strohbehn G, Bair TB, Moreland JG, Henry MD 2009 Apr Mol. Biol. Cell 8 20 2207-17

Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent.

Matsuda JJ, Filali MS, Volk KA, Collins MM, Moreland JG, Lamb FS 2008 Jan Am. J. Physiol., Cell Physiol. 1 294 C251-62

ClC-3 and IClswell are required for normal neutrophil chemotaxis and shape change.

Volk AP, Heise CK, Hougen JL, Artman CM, Volk KA, Wessels D, Soll DR, Nauseef WM, Lamb FS, Moreland JG 2008 Dec J. Biol. Chem. 49 283 34315-26

Endotoxin priming of neutrophils requires NADPH oxidase-generated oxidants and is regulated by the anion transporter ClC-3.

Moreland JG, Davis AP, Matsuda JJ, Hook JS, Bailey G, Nauseef WM, Lamb FS 2007 Nov J. Biol. Chem. 47 282 33958-67

Pre-surgical evaluation of interrupted aortic arch with 3-dimensional reconstruction of CT images.

Morriss J, Moreland J, Burkhart H, Kao S 2007 Jul Ann. Thorac. Surg. 1 84 299

Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration.

Moreland JG, Davis AP, Bailey G, Nauseef WM, Lamb FS 2006 May J. Biol. Chem. 18 281 12277-88

Neutrophil transendothelial migration in vitro to Streptococcus pneumoniae is pneumolysin dependent.

Moreland JG, Bailey G 2006 May Am. J. Physiol. Lung Cell Mol. Physiol. 5 290 L833-40

The antibacterial activity of human neutrophils and eosinophils requires proton channels but not BK channels.

Femling JK, Cherny VV, Morgan D, Rada B, Davis AP, Czirják G, Enyedi P, England SK, Moreland JG, Ligeti E, Nauseef WM, DeCoursey TE 2006 Jun J. Gen. Physiol. 6 127 659-72

Organism-specific neutrophil-endothelial cell interactions in response to Escherichia coli, Streptococcus pneumoniae, and Staphylococcus aureus.

Moreland JG, Bailey G, Nauseef WM, Weiss JP 2004 Jan J. Immunol. 1 172 426-32

CD11b and intercellular adhesion molecule-1 are involved in pulmonary neutrophil recruitment in lipopolysaccharide-induced airway disease.

Moreland JG, Fuhrman RM, Pruessner JA, Schwartz DA 2002 Oct Am. J. Respir. Cell Mol. Biol. 4 27 474-80