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2025
Anouti A, Dahshi H, Rule J, Wysocki C, Lee WM, Tujios SR. Assessment of Hemophagocytic Lympho-Histiocytosis (HLH) in the Setting of Adult Acute Liver Failure . J Viral Hepat. 2025;32(9):e70050.
Cardoso FS, Lee WM, Karvellas CJ; US Acute Liver Failure Study Group. Failure to rescue in acute liver failure: A multi-center cohort study . Liver Transpl. 2025 Aug 1;31(8):982-988.
Sandahl TD, Harrington CF, Kirk FT, et al. Diagnosing Wilson Disease in Acute Liver Failure: Comparison of Existing and Experimental Biomarkers . Am J Gastroenterol. Published online July 23, 2025.
Patel NH, Chen AY, Osiowy C, et al. Hepatitis B Virus Variants and Cytokine Patterns in Acute Liver Failure and Transplant-Free Survival . Liver Int. 2025;45(7):e70175.
Tujios SR, Wees I, Anouti A, et al. Does Prior Bariatric Surgery Predispose to Acetaminophen-Related Acute Liver Failure ? Clin Transl Gastroenterol. 2025;16(7):e00852. eCollection 2025 Jul 1.
Tujios SR, Rule JA, Sussman N, et al. Clinical and pathological spectrum of disease severity among patients with acute liver failure (ALF) undergoing deceased donor liver transplantation . Liver Transpl. Published online May 6, 2025. Online ahead of print.
Cardoso FS, Lee WM, Karvellas CJ; U.S. Acute Liver Failure Study Group. Brain CT Scan Diagnostic and Prognostic Value in Patients With Acute Liver Failure and Cerebral Edema: A Multicenter Cohort Study . Crit Care Explor. 2025;7(4):e1251.eCollection 2025 Apr 1.
Wei Z, Boateng NKK, Schmitt L, Cline H, Fonseca MTF, Newberry A, Taylor A, Adelmeijer J, Poole L, Stravitz RT, Lee WM, Lisman T Hansen KC, Luyendyk JP. Integrated cross-linking by TG2 and FXIII generates hepatoprotective fibrin(ogen) deposits in injured liver . Blood. 2025 May 22;145(21):2507-2517.
Umbaugh DS, Nguyen NT, Curry SC, Rule JA, Lee WM, Ramachandran A, Jaeschke H; Acute Liver Failure Study Group. The endothelial growth factor Angiopoietin-2i is an accurate prognostic biomarker in patients with acetaminophen-induced acute liver failure. medRxiv [Preprint]. 2025 Feb 21:2025.02.19.25322567.
Liao TJ, Xia M, Hayashi P, Pan B, Aithal GP, Lucena MI, Andrade RJ, Rule JA, Lee WM, Rakela J, Huang R, Chen M. Genetic variants of GBP4: Reduced risks for drug-induced acute liver failure in non-Finnish European population . Liver Int. 2025 Feb;45(2):e70011.
Remih K, Hufnagel FM, Karl AS, et al. Serum proteomics of adults with acute liver failure provides mechanistic insights and attractive prognostic biomarkers . JHEP Rep. 2025;7(5):101338. Published 2025 Jan 30. eCollection 2025 May.
2024
Cavazza A, Triantafyllou E, Savoldelli R, Mujib S, Jerome E, Trovato FM, Artru F, Sheth R, Huang XH, Ma Y, Dazzi F, Pirani T, Antoniades CG, Lee WM, McPhail MJ, Karvellas CJ; US Acute Liver Failure Study Group. Macrophage activation markers are associated with infection and mortality in patients with acute liver failure. Liver Int. 2024 Aug;44(8):1900-1911.
Matchett KP, Wilson-Kanamori JR, Portman JR, Kapourani CA, Fercoq F, May S, Zajdel E, Beltran M, Sutherland EF, Mackey JBG, Brice M, Wilson GC, Wallace SJ, Kitto L, Younger NT, Dobie R, Mole DJ, Oniscu GC, Wigmore SJ, Ramachandran P, Vallejos CA, Carragher NO, Saeidinejad MM, Quaglia A, Jalan R, Simpson KJ, Kendall TJ, Rule JA, Lee WM, Hoare M, Weston CJ, Marioni JC, Teichmann SA, Bird TG, Carlin LM, Henderson NC. Multimodal decoding of human liver regeneration . Nature. 2024 Jun;630(8015):158-165.
Lee WM, Barnard C, Rule JA, Orandi BJ, James LP, Stravitz RT, Durkalski V, Fontana RJ. Association of acetaminophen (paracetamol) use with severity and outcomes in patients with viral hepatitis-associated acute liver failure . Am J Gastroenterol. 2025 Mar 1;120(3):584-592.
Umbaugh DS, Nguyen NT, Curry SC, Rule JA, Lee WM, Ramachandran A, Jaeschke H; Acute Liver Failure Study Group. The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failure . Hepatology. 2024 Jun 1;79(6):1352-1364.
Cardoso FP, Toapanta D, Jimenez N, Fidalgo P, Figueiredo A, Valdivieso M, Germano N, Rule JA, Lee WM, Abraldes JG, Reverter E, Karvellas CJ. Ammonia and urea metabolism in acute liver failure: a multicenter cohort study . Liver Int. 2024 Oct;44(10):2651-2659.
Rule JA, Ajayi F, James LP, Tujios SR, Sussman NL, Rakela J, Ganger D, Bass NL, Reuben A, Stravitz RT, Lee WM. Differentiating ischemic hepatitis from acetaminophen overdose in acute liver failure: Role of acetaminophen adducts . Dig Dis Sci. 2024 Oct;69(10):3952-3961.
2023
R. Todd Stravitz, Fontana RJ, Karvellas CJ, et al. Future Directions in acute liver failure . Hepatology. 2023 Oct 1;78(4):1266-1289. Epub 2023 May 16.
Patel PV, Livingston S, Rakela JL, Stravitz RT, Reuben A, Bass NM, Tujios SR, Larson AM, Sussman NL, Rule JA, Durkalski-Mauldin VL, Lee WM, Ganger DR; Acute Liver Failure Study Group (ALFSG). Indeterminate etiology of acute liver failure in North America: Less common, still grave prognosis . Clin Transplant. 2023 Dec;37(12):e15128. Epub 2023 Sep 13.
Umbaugh DS, et al. The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failure. Hepatology. 2024 Jun 1;79(6):1352-1364. Epub 2023 Nov 1.
Orandi BJ, McLeod MC, MacLennan PA, Lee WM, Fontana RJ, Karvellas CJ, McGuire BM, Lewis CE, Terrault NM, Locke JE; US Acute Liver Failure Study Group. Association of FDA Mandate Limiting Acetaminophen (Paracetamol) in Prescription Combination Opioid Products and Subsequent Hospitalizations and Acute Liver Failure. JAMA. 2023 Mar 7;329(9):735-744.
Kwan R, Chen L, Park MJ, Su Z, Weerasinghe SVW, Lee WM, Durkalski-Mauldin VL, Fontana RJ, Omary MB. The Role of Carbamoyl Phosphate Synthetase 1 as a Prognostic Biomarker in Patients With Acetaminophen-induced Acute Liver Failure. Clin Gastroenterol Hepatol. 2023 Nov;21(12):3060-3069.e8. Epub 2023 Mar 27.
Rakela JL, Karvellas CJ, Koch DG, Vegunta S, Lee WM. Acute Liver Failure: Biomarkers Evaluated by the Acute Liver Failure Study Group. Clin Transl Gastroenterol. 2023 Apr 1;14(4):e00565.
Enke T, Livingston S, Rule J, Stravitz T, Rakela J, Bass N, Reuben A, Tujios S, Larson A, Sussman N, Durkalski V, Lee W, Ganger D. Autoimmune hepatitis presenting as acute liver failure. A 20-year retrospective review of North America . Liver Transpl. 2023 Jun 1;29(6):570-580. Epub 2023 Feb 27.
2022
Cardoso FS, Fidalgo P, Bagshaw SM, Gottfried M, Tujios S, Olson JC, et al. Persistent but not transient acute kidney injury was associated with lower transplant-free survival in patients with acute liver failure: A multicenter cohort study. Crit Care Med. 2022 Sep 1;50(9):1329-1338.
Xu L, Yang Y, Wen Y, et al. Hepatic recruitment of eosinophils and their protective function during acute liver injury. J Hepatol. 2022;77(2):344-352.
Vazquez JH, Kennon-McGill S, Byrum SD, et al. Proteomics Indicates Lactate Dehydrogenase Is Prognostic in Acetaminophen-Induced Acute Liver Failure Patients and Reveals Altered Signaling Pathways. Toxicol Sci. 2022;187(1):25-34.
Rao A, Rule JA, Hameed B, Ganger D, Fontana RJ, Lee WM. Secular Trends in Severe Idiosyncratic Drug-Induced Liver Injury in North America: An Update From the Acute Liver Failure Study Group Registry. Am J Gastroenterol. 2022;117(4):617-626.
Vazquez JH, Kennon-McGill S, Byrum SD, Mackintosh SG, Jaeschke H, Williams DK, Lee WM, Dranoff JA, McGill MR; Acute Liver Failure Study Group.Proteomics Indicates Lactate Dehydrogenase Is Prognostic in Acetaminophen-Induced Acute Liver Failure Patients and Reveals Altered Signaling Pathways Toxicol Sci. 2022 Apr 26;187(1):25-34.
von Meijenfeldt FA, Stravitz RT, Zhang J, et al. Generation of neutrophil extracellular traps in patients with acute liver failure is associated with poor outcome . Hepatology. 2022;75(3):623-633. Epub 2021 Dec 12.
Rao A, Rule JA, Cerro-Chiang G, et al. Role of Hepatitis C Infection in Acute Liver Injury/Acute Liver Failure in North America. Dig Dis Sci. 2023;68(1):304-311. Epub 2022 May 11.
Long A, Magrath M, Mihalopoulos M, et al. Changes in Epidemiology of Acetaminophen Overdoses in an Urban County Hospital After 20 Years. Am J Gastroenterol. 2022;117(8):1324-1328. Epub 2022 May 5.
Tujios S, Stravitz RT, Lee WM. Management of Acute Liver Failure: Update 2022 . Semin Liver Dis. 2022;42(3):362-378. Epub 2022 Aug 24.
Karvellas CJ, Leventhal TM, Rakela JL, et al. Outcomes of patients with acute liver failure listed for liver transplantation: A multicenter prospective cohort analysis . Liver Transpl. 2023;29(3):318-330. Epub 2022 Sep 14.
Liao TJ, Pan B, Hong H, et al. Whole Exome Sequencing Reveals Genetic Variants in HLA Class II Genes Associated With Transplant-free Survival of Indeterminate Acute Liver Failure . Clin Transl Gastroenterol. 2022;13(7):e00502. Epub 2022 Jun 2.
Wang J, Liu PH, Xu P, et al. Hypochloremia as a novel adverse prognostic factor in acute liver failure . Liver Int. 2022;42(12):2781-2790. Epub 2022 Oct 17.
2021
Karvellas CJ, Speiser JL, Tremblay M, Lee WM, Rose CF; US Acute Liver Failure Study Group. Elevated serum liver-type fatty acid binding protein levels in non-acetaminophen acute liver failure patients with organ dysfunction . Dig Dis Sci. 2021 Jan;66(1):273-283. Epub 2020 Mar 3.
Patidar KR, Davis BC, Slaven JE, Ghabril MS, Kubal CA, Lee WM, Stravitz RT. Admission Factor V Predicts Transplant-Free Survival in Acute Liver Failure . Dig Dis Sci. 2021 Feb;66(2):619-627. Epub 2020 Mar 17.
Anugwom CM, Parekh JR, Hwang C, MacConmara M, Lee WM, Leventhal TM. Comparison of clinical outcomes of induction regimens in patients undergoing liver transplantation for acute liver failure . Liver Transpl. 2021 Jan;27(1):27-33. Epub 2020 Oct 7.
Driever EG, Stravitz RT, Zhang J, Adelmeijer J, Durkalski V, Lee WM, Lisman T. VWF/ADAMTS13 imbalance, but not global coagulation or fibrinolysis, is associated with outcome and bleeding in acute liver failure . Hepatology. 2021 May;73(5):1882-1891.
Shan Z, Li L, Atkins CL, Wang M, Wen Y, Jeong J, Moreno NF, Feng D, Gui X,Zhang N, Lee CG, Elias JA, Lee WM, Gao B, Lam FW, An Z, Ju C. Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment . Elife. 2021 Jun 10:10:e68571.
Tavabie OD, Karvellas CJ, Salehi S, Speiser JL, Rose CF, Menon K, Prachalias A, Heneghan MA, Agarwal K, Lee WM, McPhail MJW, Aluvihare VR; United States Acute Liver Failure Study Group. A novel microRNA-based prognostic model outperforms standard prognostic models in patients with acetaminophen- induced acute liver failure . J Hepatol. 2021 Aug;75(2):424-434. Epub 2021 Apr 12.
Stravitz RT, Fontana RJ, Meinzer C, Durkalski V, Hanje AJ, Olson J, Koch D, Hamid B, Schilsky ML, McGuire B, Ganger D, Liou I, Karvellas CJ, Rule JA, Lisman T, Clasen K, Reuben A, Cripps MW, Lee WM; ALF Study Group. Coagulopathy, bleeding events, and outcome according to rotational thromboelastometry in patients with acute liver failure . Hepatology. 2021 Aug;74(2):937-949.
Fontana RJ, Stravitz RT, Durkalski V, Hanje J, Hameed B, Koch D, Ganger D, Olson J, Liou I, McGuire BM, Clasen K, Lee WM. Prognostic value of the 13C-methacetin breath test in adults with acute liver failure and non-acetaminophen acute liver injury . Hepatology. 2021 Aug;74(2):961-972.
MacDonald AJ, Subramanian RM, Olson JC, Speiser JL, Durkalski-Mauldin VL, Abraldes JG, Bigam DL, Flynn MM, Rapaka B, Shropshire BM, Vora RS, Karvellas CJ; U.S. Acute Liver Failure Study Group. Use of the molecular adsorbent recirculating system in acute liver failure: Results of a multi-center propensity score-matched study . Crit Care Med. 2022 Feb 1;50(2):286-295.
2020
Fontana RJ, Engle RE, Gottfried M, Hammed B, Hanje J, Durkalski V, Kleiner DE, Nguyen H, Nishimura N, Lee WM, Farci P; Acute Liver Failure Study Group. Role of Hepatitis E Virus Infection in North American Patients With Severe Acute Liver Injury . Clin Transl Gastroenterol. 2020 Nov;11(11):e00273.
Lee WM. Acetaminophen toxicity: A history of serendipity and unintended consequences . Clin Liver Dis (Hoboken). 2020 Oct 7;16(Suppl 1):34-44. eCollection 2020 Oct.
MacDonald AJ, Speiser JL, Ganger DR, Nilles KM, Orandi BJ, Larson AM, Lee WM, Karvellas CJ; US Acute Liver Failure Study Group. Clinical and Neurologic Outcomes in Acetaminophen-Induced Acute Liver Failure: A 21-Year Multicenter Cohort Study . Clin Gastroenterol Hepatol. 2021 Dec;19(12):2615-2625.e3. Epub 2020 Sep 10.
Glavind E, Gotthardt DN, Pfeiffenberger J, Sandahl TD, Bashlekova T, Willemoe GL, Hasselby JP, Weiss KH, Møller HJ, Vilstrup H, Lee WM, Schilsky ML,Ott P, Grønbæk H. The macrophage activation marker soluble CD163 is elevated and associated with liver disease phenotype in patients with Wilson's disease . Orphanet J Rare Dis. 2020 Jul 2;15(1):173.
James LP, McGill MR, Roberts DW, Hinson JA, Lee WM. Advances in biomarker development in acetaminophen toxicity . Adv Clin Chem. 2020:98:35-50. Epub 2020 Apr 27.
Montague SJ, Hicks SM, Lee CS, Coupland LA, Parish CR, Lee WM, Andrews RK, Gardiner EE. Fibrin exposure triggers αIIbβ3-independent platelet aggregate formation, ADAM10 activity and glycoprotein VI shedding in a charge- dependent manner . J Thromb Haemost. 2020 Jun;18(6):1447-1458. Epub 2020 Apr 16.
Casey LC, Fontana RJ, Aday A, Nelson DB, Rule JA, Gottfried M, Tran M, Lee WM, Acute Liver Failure Study Group. Acute liver failure (ALF) in pregnancy: How much is pregnancy related? Hepatology. 2020 Oct;72(4):1366-1377. Epub 2020 Oct 5.
Puri P, Lee WM, Fontana RJ, Kim NK, Durkalski V, McGuire BM, Liou I, Pezzia C, Stravitz RT; Acute Liver Failure Study Group. Alcohol consumption is associated with the severity and outcome of acute liver injury/ failure . Liver Int. 2020 Feb;40(2):360-367. Epub 2019 Dec 23.
Ren Y, Xu Y, Lee WM, Di Bisceglie AM, Fan X. In-depth serum virome analysis in patients with acute liver failure with indeterminate etiology . Arch Virol. 2020 Jan;165(1):127-135. Epub 2019 Nov 18.
2019
Dong V, Sun K, Gottfried M, Cardoso FS, McPhail MJ, Stravitz RT, Lee WM, Karvellas CJ. Significant lung injury and its prognostic significance in acute liver failure: A cohort analysis. Liver Int. 2020 Mar;40(3):654-663. Epub 2019 Oct 13.
Rakela J, Rule J, Ganger D, Lau J, Cunningham J, Dehankar M, Baheti S, Lee WM. Whole exome sequencing among 36 patients with indeterminate acute liver failure: A pilot study. Clin Transl Gastroenterol. 2019 Oct;10(10):e00087.
Simmons OK, Meinzer C, Rule J, Lee WM and ALFSG. Liver transplantation for acetaminophen-induced acute liver failure: role of psychiatric comorbidity in listing decisions and outcomes. Dig Dis Sci. 2020 Jun;65(6):1861-1868. Epub 2019 Nov 2.
Puri P, Lee WM, Fontana RJ, Kim NK, Durkalski V, McGuire BM, Liou I, Pezzia C, Stravitz RT and ALFSG. Alcohol consumption is associated with the severity and outcome of acute liver injury/failure. Liver Int. 2020 Feb;40(2):360-367. Epub 2019 Dec 23.
Camarata M, Gottfried M, Rule JA, Ala A, Lee WM, Stravitz RT, Schilsky ML. Outcomes of acute liver injury (ALI) in adults due to Wilson Disease: Is survival without transplant possible? Liver Transpl. 2020 Mar;26(3):330-336.
Stravitz RT, Lee WM. Acute Liver Failure: Seminar . Lancet. 2019;394:869–81
Singh S, Hynan LS, Rule JA, Lee WM. Changes in Alpha-fetoprotein and Gc-Globulin in Relation to Outcomes in Non-Acetaminophen Acute Liver Failure . Liver Int. 2019 Dec;39(12):2368-2373. Epub 2019 Sep 10.
Slowik V, Borude P, Jaeschke H, Woolbright BL, Lee WM, Apte U; Acute Liver Failure Study Group. Leukocyte cell derived chemotaxin-2 (Lect2) as a predictor of survival in adult acute liver failure . Transl Gastroenterol Hepatol. 2019 Mar 20:4:17. eCollection 2019.
Ajmera V, Huang H, Dao D, Feld JJ, Lau DT, Patel K, Rule JA, Daly M, Lee WM, Chung RT. Host Genetic Variant in CXCL16 May Be Associated With Hepatitis B Virus-Related Acute Liver Failure . Cell Mol Gastroenterol Hepatol. 2019;7(2):477-479.e4. Epub 2018 Oct 17.
Leventhal TM, Gottfried M, Olson JC, Subramanian RM, Hameed B, Lee WM; Acute Liver Failure Study Group. Acetaminophen is Undetectable in Plasma From More Than Half of Patients Believed to Have Acute Liver Failure Due to Overdose . Clin Gastroenterol Hepatol. 2019 Sep;17(10):2110-2116. Epub 2019 Feb 5.
Spivak I, Arora J, Meinzer C, Durkalski-Mauldin V, Lee WM, Trautwein C, Fontana RJ, Strnad P; Acute Liver Failure Study Group (ALFSG). Low Serum Hepcidin Is Associated With Reduced Short-Term Survival in Adults With Acute Liver Failure . Hepatology. 2019 May;69(5):2136-2149. Epub 2019 Mar 15.
Little L, Rule J, Peng L, Gottfried M, Lee WM; Acute Liver Failure Study Group. Herpes Simplex Virus-Associated Acute Liver Failure Often Goes Unrecognized . Hepatology. 2019 Feb;69(2):917-919. Epub 2019 Jan 4.
2018
Ganger DR, Rule J, Rakela J, Bass N, Reuben A, Stravitz RT, Sussman N, Larson AM, James L, Chiu C, Lee WM; Acute Liver Failure Study Group. Acute Liver Failure of Indeterminate Etiology: A Comprehensive Systematic Approach by An Expert Committee to Establish Causality . Am J Gastroenterol. 2018 Sep;113(9):1319. Epub 2018 Jun 27.
Rubin JB, Hameed B, Gottfried M, Lee WM, Sarkar M; Acute Liver Failure Study Group. Acetaminophen-induced Acute Liver Failure Is More Common and More Severe in Women . Clin Gastroenterol Hepatol. 2018 Jun;16(6):936-946. Epub 2017 Dec 2.
Stravitz RT, Ellerbe C, Durkalski V, Schilsky M, Fontana RJ, Peterseim C, Lee WM; Acute Liver Failure Study Group. Bleeding complications in acute liver failure . Hepatology. 2018 May;67(5):1931-1942. Epub 2018 Mar 26.
Kok B, Lester ELW, Lee WM, Hanje AJ, Stravitz RT, Girgis S, et al; United States Acute Liver Failure Study Group. Acute Liver Failure from Tumor Necrosis Factor-α Antagonists: Report of Four Cases and Literature Review . Dig Dis Sci. 2018 Jun;63(6):1654-1666. Epub 2018 Mar 21.
Stravitz RT, Gottfried M, Durkalski V, Fontana RJ, Hanje AJ, Koch D, Hameed B, Ganger D, Subramanian RM, Bukofzer S, Ravis WR, Clasen K, Sherker A, Little L, Lee WM; Acute Liver Failure Study Group. Safety, tolerability, and pharmacokinetics of L-ornithine phenylacetate in patients with acute liver injury/failure and hyperammonemia . Hepatology. 2018 Mar;67(3):1003-1013. Epub 2018 Jan 30.
Bonkovsky HL, Barnhart HX, Foureau DM, Steuerwald N, Lee WM, Gu J, Fontana RJ, Hayashi PJ, Chalasani N, Navarro VM, Odin J, Stolz A, Watkins PB, Serrano J; US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group. Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group . PLoS One. 2018 Oct 25;13(10):e0206389. eCollection 2018.
2017
Lee WM. Acetaminophen (APAP) hepatotoxicity — Isn't it time for APAP to go away ? J Hepatol. 2017 Dec;67(6):1324-1331. Epub 2017 Jul 20.
Somasekar S, Lee D, Rule J, Naccache SN, Stone M, Busch MP, Sanders C, Lee WM, Chiu CY. Viral surveillance in serum samples from patients with acute liver failure by metagenomic next-generation sequencing . Clin Infect Dis. 2017 Oct 16;65(9):1477-1485.
Karvellas CJ, Speiser JL, Tremblay M, Lee WM, Rose CF; US Acute Liver Failure Study Group. The association between FABP7 serum levels with survival and neurological complications in acetaminophen-induced acute liver failure: a nested case-control study . Ann Intensive Care. 2017 Oct 5;7(1):99.
Pezzia C, Sanders C, Welch S, Bowling A, Lee WM; Acute Liver Failure Study Group. Psychosocial and behavioral factors in acetaminophen-related acute liver failure and liver injury . J Psychosom Res. 2017 Oct:101:51-57. Epub 2017 Aug 4.
Cardoso, FS, Gottfried M, Tujios S, Olson JC, Karvellas CJ, for the US Acute Liver Failure Study Group. Continuous renal replacement therapy is associated with reduced serum ammonia levels and mortality in acute liver failure . Hepatology. 2018 Feb;67(2):711-720. Epub 2017 Dec 26.
Karvellas CJ, Speiser JL, Tremblay M, Lee WM, Rose CF; US Acute Liver Failure Study Group. Elevated FABP1 serum levels are associated with poorer survival in acetaminophen-induced acute liver failure. Hepatology. 2017 Mar;65(3):938-949. Epub 2017 Jan 19.
Parekh J, Matei VM, Canas-Coto A, Friedman D, Lee WM; and the Acute Liver Failure Study Group. Budd-Chiari syndrome causing acute liver failure: A multicenter case series. Liver Transpl. 2017 Feb;23(2):135-142.
Roberts DW, Lee WM, Hinson JA, Bai S, Swearingen CJ, Stravitz RT, Reuben A, Letzig L, Simpson PM, Rule J, Fontana RJ, Ganger D, Reddy KR, Liou I, Fix O, James LP. An immunoassay to rapidly measure acetaminophen protein adducts accurately identifies patients with acute liver injury or failure. Clin Gastroenterol Hepatol. 2017 Apr;15(4):555-562.e3. Epub 2016 Sep 15.
Davis BC, Tillman H, Chung RT, Stravitz RT, Reddy KR, Fontana RJ, McGuire B, Davern T, Lee WM. Heat stroke leading to acute liver injury and failure: A case series from the Acute Liver Failure Study Group. Liver Int. 2017 Apr;37(4):509-513. Epub 2017 Feb 17.
Randesi M, Levran O, Correa da Rosa J, Hankins J, Rule J, Kreek MJ, Lee WM. Association of variants of arginine vasopressin and arginine vasopressin receptor 1A, with severe acetaminophen liver injury. Cell Mol Gastroenterol Hepatol. 2017 Jan 24;3(3):500-505.
Koch DG, Speiser JL, Durkalski V, Fontana RJ, Davern T, McGuire B, et al. The natural history of acute liver injury . Am J Gastroenterol. 2017 Sep;112(9):1389-1396. Epub 2017 Apr 25.
Karvellas CJ, Cardoso FS, Gottfried M, Reddy KR, Hanje AJ, Ganger D, Lee WM; US Acute Liver Failure Study Group. HBV-associated acute liver failure after immunosuppression and risk of death. Clin Gastroenterol Hepatol. 2017 Jan;15(1):113-122. Epub 2016 Jun 13.
2016
Fix OK, Liou I, Karvellas CJ, Ganger DR, Forde KA, Subramanian RM, Boylan A, Hanje J, Stravitz RT, Lee WM; Acute Liver Failure Study Group. Development and Pilot of a Checklist for Management of Acute Liver Failure in the Intensive Care Unit. PLoS One. 2016 May 13;11(5):e0155500. eCollection 2016.
Fontana RJ, Engle RE, Scaglione S, Araya V, Shaikh O, Tillman H, Attar N, Purcell RH, Lee WM; US Acute Liver Failure Study Group. The role of hepatitis E virus infection in Adult Americans with acute liver failure. Hepatology. 2016 Dec;64(6):1870-1880. Epub 2016 Jun 23.
Koch DG, Tillman H, Durkalski V, Lee WM, Reuben A. Development of a Model to Predict Transplant-free Survival of Patients with Acute Liver Failure. Clin Gastroenterol Hepatol. 2016 Aug;14(8):1199-1206.e2. Epub 2016 Apr 13.
Hillman L, Gottfried M, Whitsett M, Rakela J, Schilsky M, Lee WM, Ganger D. Clinical Features and Outcomes of Complementary and Alternative Medicine Induced Acute Liver Failure and Injury. Am J Gastroenterol. 2016 Jul;111(7):958-65. Epub 2016 Apr 5.
Ruben A, Tillman H, Fontana RJ, Davern T, McGuire B, Stravitz RT, Durkalski V, Larson AM, Liou I, Fix O, Schilsky M, McCashland t, Hay JE, Murray N, Shaikh OS, Granger D, Zaman A, Han SB, Chung RT, Smith A, Brown R, Crippin J, Harrison ME, Koch DG, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hassanein T, Hanje AJ, Olson J, Subramanian R, Karvellas CJ, Hameed B, Sherker AH, Robuck P, Lee WM. Outcomes in Adults With Acute Liver Failure Between 1998 and 2013: An Observational Cohort Study. Ann Intern Med. 2016 Jun 7;164(11):724-32. Epub 2016 Apr 5.
Karvellas CJ, Tillman H, Leung AA, Lee WM, Schilsky ML, Hameed B, Stravitz RT, McGuire BM, Fix OK; United States Acute Liver Failure Study Group. Acute Liver Injury and Acute Liver Failure from Mushroom Poisoning in North America. Liver Int. 2016 Jul;36(7):1043-50. Epub 2016 Mar 4.
Maina I, Rule JA, Wians Jr, FH, Poirier M, Grant L, Lee WM, for the Acute Liver Failure Study Group. α-Glutathione S-Transferase: A new biomarker for liver injury ? J Appl Lab Med. 2016 Sep 1;1(2):119-128.
2015
Rosen HR, Biggins SW, Niki T, Gralla J, Hillman H, Hirashima M, Schilsky M, Lee WM; Acute Liver Failure Study Group (ALFSG). Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure. Clin Gastroenterol Hepatol. 2016 Apr;14(4):606-612.e3. Epub 2015 Oct 20.
Stravitz RT, Ellerbe C, Durkalski V, Reuben A, Lisman T, Lee WM; Acute Liver Failure Study Group. Thromobcytopenia is Associated with Multi-organ System Failure in Patients With Acute Liver Failure. Clin Gastroenterol Hepatol. 2016 Apr;14(4):613-620.e4. Epub 2015 Dec 10.
Reddy KR, Ellerbe C, Schilsky M, Stravitz RT, Fontana RJ, Durkalski V, Lee WM; Acute Liver Failure Study Group. Determinants of Outcome Among Patients with Acute Liver Failure Listed for Liver Transplantation in the US. Liver Transpl. 2016 Apr;22(4):505-15.
Kaur G, Leslie EM, Tillman H, Lee WM, Swanlund DP, Karvellas CJ; US Acute Liver Failure Study Group. Detection of Ophthalmic Acid in Serum from Acetaminophen-Induced Acute Liver Failure Patients Is More Frequent in Non-Survivors. PLoS One. 2015 Sep 25;10(9):e0139299. eCollection 2015.
Rule JA, Hynan LS, Attar N, Sanders C, Korzun WJ, Lee WM; Acute Liver Failure Study Group. Procalcitonin Identifies Cell Injury, Not Bacterial Infection, in Acute Liver Failure. PLoS One. 2015 Sep 22;10(9):e0138566. eCollection 2015.
Serper M, Wolf MS, Parikh NA, Tillman H, Lee WM, Ganger DR. Risk Factors, Clinical Presentation, and Outcomes in Overdose With Acetaminophen Alone or With Combination Products: Results From the Acute Liver Failure Study Group. J Clin Gastroenterol. 2016 Jan;50(1):85-91.
Speiser JL, Lee WM, Karvellas CJ; US Acute Liver Failure Study Group. Predicting Outcome on Admission and Post-Admission for Acetaminophen-Induced Acute Liver Failure Using Classification and Regression Tree Models. PLoS One. 2015 Apr 17;10(4):e0122929. eCollection 2015.
Basta G, Del Turco S, Navarra T, Lee WM; Acute Liver Failure Study Group. Circulating Levels of Soluble Rage and Rage-Ligands in Patients with Acute Liver Failure . Liver Transpl. 2015 Jun;21(6):847-54.
Srungaram P, Rule JA, Yuan HJ, Reimold A, Dahl B, Sanders C, Lee WM; Acute Liver Failure Study Group. Plasma osteopontin in acute liver failure . Cytokine. 2015 Jun;73(2):270-6. Epub 2015 Mar 21.
Foureau DM, Walling TL, Maddukuri V, Anderson W, Culbreath K, Kleiner DE, Ahrens WA, Jacobs C, Watkins PB, Fontana RJ, Chalasani N, Talwalkar J, Lee WM, Stolz A, Serrano J, Bonkovsky HL. Comparative analysis of portal hepatic infiltrating leucocytes in acute drug-induced liver injury, idiopathic autoimmune and viral hepatitis. Clin Exp Immunol. 2015 Apr;180(1):40-51.
Speiser JL, Durkalski VL, Lee WM. Random forest classification of etiologies for an orphan disease. Stat Med. 2015 Feb 28;34(5):887-99.
2014
Karvellas CJ, Stravitz RT, Battenhouse H, Lee WM, Schilsky ML; for the US Acute Liver Failure Study Group. Therapeutic hypothermia in acute liver failure: A multicenter retrospective cohort analysis. Liver Transpl. 2015 Jan;21(1):4-12.
Rich NE, Sanders C, Hughes RS, Fontana RJ, Stravitz RT, Fix O, Han SH, Naugler WE, Zaman A, Lee WM. Malignant Infiltration of the Liver Presenting as Acute Liver Failure. Clin Gastroenterol Hepatol. 2015 May;13(5):1025-8. Epub 2014 Sep 30.
Woolbright BL, McGill MR, Staggs VS, Winefield RD, Gholami P, Olyaee M, Sharpe MR, Curry SC, Lee WM, Jaeschke H; the Acute Liver Failure Study Group. Glycodeoxycholic Acid Levels as Prognostic Biomarker in Acetaminophen-induced Acute Liver Failure Patients. Toxicol Sci. 2014 Dec;142(2):436-44. Epub 2014 Sep 19.
Laursen TL, Sandahl TD, Støy S, Schiødt FV, Lee WM, Vilstrup H, Thiel S, Grønbaek H; U.S. Acute Liver Failure Study Group. Circulating mannan-binding lectin, M-, L-, H-ficolin, and collectin-liver-1 levels in patients with acute liver failure. Liver Int. 2015 Mar;35(3):756-63. Epub 2014 Sep 30.
Fontana RJ, Ellerbe C, Durkalski VE, Rangnekar A, Reddy KR, Stravitz T, McGuire B, Davern T, Reuben A, Liou I, Fix O, Ganger DR, Chung RT, Schilsky M, Han S, Hynan LS, Sanders C, Lee WM; The US Acute Liver Failure Study Group. 2-year outcomes in Initial survivors with Acute Liver failure: Results from a Prospective, Multicenter Study. Liver Int. 2015 Feb;35(2):370-80. Epub 2014 Jul 28.
Tujios SR, Hynan LS, Vazquez MA, Larson AM, Seremba E, Sanders CM, Lee WM; Acute Liver Failure Study Group. Risk Factors and Outcomes of Acute Kidney Injury in Patients with Acute Liver Failure. Clin Gastroenterol Hepatol. 2015 Feb;13(2):352-9.Epub 2014 Jul 11.
Long D, Fix OK, Deng X, Seielstad M, Lauring AS; The Acute Liver Failure Study Group. Whole genome sequencing to identify host genetic risk factors for severe outcomes of hepatitis a virus infection. J Med Virol. 2014 Oct;86(10):1661-8. Epub 2014 Jun 30.
Mellinger JL, Rossaro L, Naugler WE, Nadig SN, Appelman H, Lee WM, Fontana RJ. Epstein-Barr Virus (EBV) Related Acute Liver Failure: A Case Series from the US Acute Liver Failure Study Group . Dig Dis Sci. 2014 Jul;59(7):1630-7. Epub 2014 Jan 25.
McGill MR, Staggs VS, Sharpe MR, Lee WM, Jaeschke H; Acute Liver Failure Study Group. Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome . Hepatology. 2014 Oct;60(4):1336-45. Epub 2014 Aug 25.
Dubin PH, Yuan H, Devine RK, Hynan LS, Jain MK, Lee WM; the Acute Liver Failure Study Group. Micro-RNA-122 levels in acute liver failure and chronic hepatitis J Med Virol. 2014 Sep;86(9):1507-14. Epub 2014 Jun 4.
Karvellas CJ, Fix OK, Battenhouse H, Durkalski V, Sanders C, Lee WM. Outcomes and complications of intracranial pressure monitoring in acute liver failure: a retrospective cohort study . Crit Care Med. 2014 May;42(5):1157-67.
Karvellas CJ, Cavazos J, Battenhouse H, Durkalski V, Balko J, Sanders C, Lee WM, the Acute Liver Failure Study Group. The Effects of Antimicrobial Prophylaxis and Blood Stream Infections in Acute Liver Failure: A Retrospective Cohort . Clin Gastroenterol Hepatol. 2014 Nov;12(11):1942-9.e1. Epub 2014 Mar 25.
Metushi IG, Sanders C, Lee WM, Uetrecht J. Detection of Anti-Isoniazid and Anti-CYP Antibodies in Patients with Isoniazid-Induced Liver Failure . Hepatology. 2014 Mar;59(3):1084-93. Epub 2014 Jan 27.
Karkhanis J, Verna EC, Chang MS, Stravitz RT, Schilsky M, Lee WM, Brown RS Jr; the Acute Liver Failure Study Group. Steroid use in acute liver failure . Hepatology . 2014 Feb;59(2):612-21. Epub 2013 Dec 24.
Court MH, Peter I, Hazarika S, Vasiadi M, Greenblatt DJ, Lee W. Candidate gene polymorphisms in patients with acetaminophen-induced acute liver failure . Drug Metab Dispos. 2014 Jan;42(1):28-32. Epub 2013 Oct 8.
2013
Stravitz RT, Sanyal AJ, Reisch J, Bajaj JS, Mirshahi F, Cheng J, Lee WM and the Acute Liver Failure Study Group. Effects of N-acetylcysteine on cytokines in non-acetaminophen acute liver failure: potential mechanism of improvement in transplant-free survival . Liver Int. 2013 Oct;33(9):1324-31. Epub 2013 Jun 19.
Rangnekar AS, Ellerbe C, Durkalski V, McGuire B, Lee WM, Fontana RJ. Quality of life is significantly impaired in long-term survivors of acute liver failure and particularly in acetaminophen-overdose patients . Liver Transpl. 2013 Sep;19(9):991-1000. Epub 2013 Aug 18.
Singh S, Hynan LS, Lee WM. Improvements in hepatic serological biomarkers are associated with clinical benefit of intravenous N-acetylcysteine in early stage non-acetaminophen acute liver failure . Dig Dis Sci. 2013 May;58(5):1397-402. Epub 2013 Jan 17.
Court MH, Freytsis M, Wang X, Peter I, Guillemette C, Hazarika S, Duan SX, Greenblatt DJ, Lee WM. The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure . J Pharmacol Exp Ther. 2013 May;345(2):297-307. Epub 2013 Feb 13.
2012
Stravitz RT, Lisman T, Luketic VA, Sterling RK, Puri P, Fuchs M, Ibrahim A, Lee WM, Sanyal AJ. Minimal effects of acute liver injury/acute liver failure on hemostasis as assessed by thromboelastography . J Hepatol. 2012 Jan;56(1):129-36. Epub 2011 May 19.
Taylor RM, Tujios S, Jinjuvadia K, Davern T, Shaikh OS, Han S, Chung RT, Lee WM, Fontana RJ. Short and long-term outcomes in patients with acute liver failure due to ischemic hepatitis . Dig Dis Sci. 2012 Mar;57(3):777-85. Epub 2011 Sep 27.
Dao DY, Hynan LS, Yuan HJ, Sanders C, Balko J, Attar N, Lok ASF, Word RA, Lee WM. Two distinct subtypes of hepatitis B virus-related acute liver failure are separable by quantitative serum IgM anti-HBc and HBV DNA levels . Hepatology. 2012 Mar;55(3):676-84. Epub 2012 Jan 31.
Dao DY, Seremba E, Ajmera V, Sanders C, Hynan LS, Lee WM and the ALFSG. Use of nucleoside (tide) analogues in patients with hepatitis B-related acute liver failure . Dig Dis Sci. 2012 May;57(5):1349-57. Epub 2011 Dec 25.
Lee WM, Stravitz RT, Larson AM. Introduction to the revised American Association for the Study of Liver Diseases Position Paper on Acute Liver Failure 2011 . Hepatology. 2012 Mar;55(3):965-7.
Chung RY, Stravitz, RT, Fontana RJ, Schiodt FV, Mehal W, Reddy R, Lee WM. Pathogenesis of Liver Injury in Acute Liver Failure . Gastroenterology. 2012 Sep;143(3):e1-e7. Epub 2012 Jul 13.
Rutherford A, King LY, Hynan LS, Vedvyas C, Lin W, Lee WM, Chung RT; ALF Study Group. Development of an accurate index for predicting outcomes of patients with acute liver failure . Gastroenterology. 2012 Nov;143(5):1237-1243. Epub 2012 Aug 8.
2011
Ajmera V, Xia G, Vaughan G, Forbi J, Ganova-Raeva LM, Khudyakov Y, Opio CK, Taylor R, Restrepo R, Munoz S, Fontana RJ, Lee WM and the Acute Liver Failure Study Group. What factors determine the severity of hepatitis A related acute liver failure ? J Viral Hepat. 2011 Jul;18(7):e167-74. Epub 2010 Dec 8.
Khandelwal N, James LP, Sanders C, Larson AM, Lee WM, Acute Liver Failure Study Group. Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure . Hepatology. 2011 Feb;53(2):567-76. Epub 2011 Jan 10.
Stravitz RT, Lefkowitch JH, Fontana RJ, Gershwin ME, Leung PS, Sterling RK, Manns MP, Norman GL, Lee WM; and the Acute Liver Failure Study Group. Autoimmune acute liver failure: proposed clinical and histological criteria , Hepatology. 2011 Feb;53(2):517-26. Epub 2011 Jan 5.
2010
Gregory B, Larson AM, Reisch J, Lee WM and the Acute Liver Failure Study Group. Acetaminophen dose does not predict outcome in acetaminophen-induced acute liver failure . J Investig Med. 2010 Jun;58(5):707-10.
Reuben A, Koch DG, Lee WM; Acute Liver Failure Study Group. Drug-induced acute liver failure: results of a U.S. multicenter, prospective study . Hepatology. 2010 Dec;52(6):2065-76. Epub 2010 Oct 14.
Strnad P, Zhou Q, Hanada S, Lazzeroni LC, Zhong BH, So P, Davern TJ, Lee WM; Acute Liver Failure Study Group, Omary MB. Keratin variants predispose to acute liver failure and adverse outcome: race and ethnic associations . Gastroenterology. 2010 Sep;139(3):828-35, 835.e1-3. Epub 2010 Jun 9.
2009
Cote, GA, Gottstein, JH, Daud, A, Lee, WM, Blei, AT and the Acute Liver Failure Study Group. The Role of Etiology in the Hyperamylasemia of Acute Liver Failure . Am J Gastroenterol. 2009 Mar;104(3):592-7. Epub 2009 Feb 17.
Lee WM, Hynan LS, Rossaro L, Fontana RJ, Stravitz RT, Larson AM, Davern TL III, Murray NG, McCashland T, Reisch J, Robuck PR and the ALFSG. Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure . Gastroenterology. 2009 Sep;137(3):856-64, 864.e1. Epub 2009 Jun 12.
Forde KA, Reddy KR, Troxel AB, Sanders CM, Lee W, and the Acute Liver Failure Study Group. Racial and ethnic differences in presentation, etiology and outcomes of acute liver failure in the United States . Clin Gastroenterol Hepatol. 2009 Oct;7(10):1121-6. Epub 2009 Jun 23.
Schiødt FV, Chung RT, Schilsky ML, Hay JE, Christensen E, Lee WM and the ALFSG. Outcome of Acute liver failure in the elderly . Liver Transpl. 2009 Nov;15(11):1481-7.
James LP, Letzig L, Simpson PM, Capparelli E, Roberts DW, Hinson JA, Davern TJ, Lee WM. Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure . Drug Metab Dispos. 2009 Aug;37(8):1779-84 Epub 2009 May 13.
Li J, Zhu X, Liu F, Cai P, Sanders C, Lee WM, Uetrecht J.Cytokine and autoantibody patterns in acute liver failure . J Immunotoxicol. 2010 Jul-Sep;7(3):157-64.
2008
Lee WM, Squires RH, Jr., Nyberg SL, Doo E, Hoofnagle JH. Acute liver failure: Summary of a workshop . Hepatology. 2008 Apr;47(4):1401-15.
Polson J, Wians FH Jr, Orsulak P, Fuller D, Murray NG, Koff JM, Khan AI, Balko JA, Hynan LS, Lee WM; Acute Liver Failure Study Group. False positive acetaminophen concentrations in patients with liver injury . Clin Chim Acta. 2008 May;391(1-2):24-30. Epub 2008 Jan 26.
Korman JD, Volenberg I, Balko J, Webster J, Schiodt FV, Lee WM, Schilsky ML and the Pediatric and Adult ALF Study Groups. Screening for Wilson disease in acute liver failure: A comparison of currently available diagnostic tests . Hepatology. 2008 Oct;48(4):1167-74.
Levitsky J, Thadareddy A, Lakeman FD, Whitley RJ, Luby JP, Lee WM, Fontana RJ, Blei AT, Ison MG. Detection and diagnosis of herpes virus infection in adults with acute liver failure . Liver Transpl. 2008 Oct;14(10):1498-504.
2007
Leung PS, Rossaro L, Davis PA, Park O, Tanaka A, Kikuchi K, Miyakawa H, Norman GL, Lee W, Gershwin ME; Acute Liver Failure Study Group. Antimitochondrial antibodies in acute liver failure: implications for primary biliary cirrhosis . Hepatology. 2007 Nov;46(5):1436-42.
Møller HJ, Grønbaek H, Schiødt FV, Holland-Fischer P, Schilsky M, Munoz S, Hassanein T, Lee WM; U.S. Acute Liver Failure Study Group. Soluble CD163 from activated macrophages predicts mortality in acute liver failure . J Hepatol 2007; 47:671-676. PMID: 17629586. PMCID: PMC2179895.
Parekh NK, Hynan LS, De Lemos J, Lee WM; Acute Liver Failure Study Group. Elevated troponin I levels in acute liver failure: is myocardial injury an integral part of acute liver failure ? J Hepatol. 2007 Nov;47(5):671-6. Epub 2007 Jun 21.
Rutherford AE, Hynan LS, Borges CB, Forcione DG, Blackard JT, Lin W, Gorman AR, Shaikh OS, Reuben A, Harrison E, Reddy KR, Le WM, Chung RT; ALF Study Group. Serum apoptosis markers in acute liver failure: a pilot study . Clin Gastroenterol Hepatol. 2007 Dec;5(12):1477-83. Epub 2007 Oct 29.
Schiødt FV, Bangert K, Shakil AO, McCashland T, Murray N, Hay JE, Lee WM; Acute Liver Failure Study Group. Predictive value of actin-free Gc-globulin in acute liver failure . Liver Transpl. 2007 Sep;13(9):1324-9.
Stravitz RT, Kramer AH, Davern T, Shaikh AO, Caldwell SH, Mehta RL, Blei AT, Fontana RJ, McGuire BM, Rossaro L, Smith AD, Lee WM; Acute Liver Failure Study Group. Intensive care of patients with acute liver failure: Recommendations of the U.S. Acute Liver Failure Study Group . Crit Care Med. 2007 Nov;35(11):2498-508.
2006
Davern TJ 2nd, James LP, Hinson JA, Polson J, Larson AM, Fontana RJ, Lalani E, Munoz S, Shakil AO, Lee WM; Acute Liver Failure Study Group. Measurement of serum acetaminophen-protein adducts in patients with acute liver failure . Gastroenterology. 2006 Mar;130(3):687-94.
James LP, Alonso EM, Hynan LS, Hinson JA, Davern TJ, Lee WM, Squires RH; Pediatric Acute Liver Failure Study Group. Detection of acetaminophen protein adducts in children with acute liver failure of indeterminate cause . Pediatrics. 2006 Sep;118(3):e676-81.
Lee WM, Brown KE, Young NS, Dawson GJ, Schlauder GG, Gutierrez RA, Fontana R, Rossaro L, Davern T, Lalani E; Acute Liver Failure Study Group. Brief report: no evidence for parvovirus B19 or hepatitis E virus as a cause of acute liver failure . Dig Dis Sci. 2006 Oct;51(10):1712-5.
Rutherford A, Davern T, Hay JE, Murray NG, Hassanein T, Lee WM, Chung RT; Acute Liver Failure Study Group. Influence of high body mass index on outcome in acute liver failure . Clin Gastroenterol Hepatol. 2006 Dec;4(12):1544-9. Epub 2006 Sep 25.
Schiødt FV, Ostapowicz G, Murray N, Satyanarana R, Zaman A, Munoz S, Lee WM. Alpha-fetoprotein and prognosis in acute liver failure . Liver Transpl. 2006 Dec;12(12):1776-81.
Taylor RM, Davern T, Munoz S, Han SH, McGuire B, Larson AM, Hynan L, Lee WM, Fontana RJ; US Acute Liver Failure Study Group. Fulminant hepatitis A virus infection in the United States: Incidence, prognosis, and outcomes . Hepatology. 2006 Dec;44(6):1589-97.
2005
Fontana RJ, Shakil AO, Greenson JK, Boyd I, Lee WM. Acute liver failure due to amoxicillin and amoxicillin/clavulanate . Dig Dis Sci. 2005 Oct;50(10):1785-90.
Larson AM, Polson J, Fontana RJ, Davern TJ, Lalani E, Hynan LS, Reisch JS, Schiødt FV, Ostapowicz G, Shakil AO, Lee WM; Acute Liver Failure Study Group. Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study . Hepatology. 2005 Dec;42(6):1364-72.
Schiødt FV, Rossaro L, Stravitz RT, Shakil AO, Chung RT, Lee WM; Acute Liver Failure Study Group. Gc-globulin and prognosis in acute liver failure . Liver Transpl. 2005 Oct;11(10):1223-7.
Wai CT, Fontana RJ, Polson J, Hussain M, Shakil AO, Han SH, Davern TJ, Lee WM, Lok AS; US Acute Liver Failure Study Group. Clinical outcome and virological characteristics of hepatitis B-related acute liver failure in the United States . J Viral Hepat. 2005 Mar;12(2):192-8.
2004
2003
Schiødt FV, Balko J, Schilsky M, et al. Thrombopoietin in acute liver failure . Hepatology. 2003;37(3):558-561.
Schiødt FV, Davern TJ, Shakil AO, McGuire B, Samuel G, Lee WM. Viral hepatitis-related acute liver failure . Am J Gastroenterol. 2003;98(2):448-453.
Umemura T, Tanaka E, Ostapowicz G, et al. Investigation of SEN virus infection in patients with cryptogenic acute liver failure, hepatitis-associated aplastic anemia, or acute and chronic non-A-E hepatitis . J Infect Dis. 2003;188(10):1545-1552.
Vaquero J, Jordano Q, Lee WM, Blei AT; US Acute Liver Failure Study Group. Serum protein S-100b in acute liver failure: Results of the US Acute Liver Failure Study group . Liver Transpl. 2003;9(8):887-888.
2002
Ostapowicz G, Fontana RJ, Schiødt FV, Larson A, Davern TJ, Han SH, McCashland TM, Shakil AO, Hay JE, Hynan L, Crippin JS, Blei AT, Samuel G, Reisch J, Lee WM; U.S. Acute Liver Failure Study Group. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States . Ann Intern Med. 2002 Dec 17;137(12):947-54.
Teo EK, Ostapowicz G, Hussain M, Lee WM, Fontana RJ, Lok AS; US ALF Study Group (Acute Liver Failure). Hepatitis B infection in patients with acute liver failure in the United States . Hepatology. 2001 Apr;33(4):972-6.
2001
2000
1999
Fontana RJ, McCashland TM, Benner KG, Appelman HD, Gunartanam NT, Wisecarver JL, Rabkin JM, Lee WM. Acute liver failure associated with prolonged use of bromfenac leading to liver transplantation . Liver Transpl Surg. 1999 Nov;5(6):480-4.
Schiodt FV, Atillasoy E, Shakil AO, Schiff ER, Caldwell C, Kowdley KV, Stribling R, Crippin JS, Flamm S, Somberg KA, Rosen H, McCashland TM, Hay JE, Lee WM. Etiology and outcome for 295 patients with acute liver failure in the United States . Liver Transpl Surg. 1999 Jan;5(1):29-34.