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Mission
- Understand how disseminated tumor cells survive in distal organs as residual or latent disease.
- Define the molecular and metabolic dependencies of metastasis initiating cells.
- To translate our findings into improved diagnostic and therapeutic modalities for treating residual disease and metastasis.
Research Projects
- Mechanisms promoting invasion, dissemination, and metastatic competence.
- Disseminated tumor cells and their ecosystem during metastatic latency.
- Mechanisms underlying metastatic dormancy, treatment resistance, and outgrowth of brain metastasis.
- Metabolic and epigenetic mediators of metastatic latency.
