![Neurons - Optica](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka1_neurons.jpeg?h=2a479378&itok=lRtOrXYp)
Dean et. al., the latest manuscript selected for the cover of Optica. Imaging subcellular dynamics with fast and light-efficient volumetrically parallelized microscopy (Vol. 4, Issue 2, 2017).
![Grazing Incidence](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka2_grazing-cell-struct.jpeg?h=1b830d40&itok=gmUTtJ5U)
Using a combination of structured illumination and TIRF microscopy, the Fiolka lab demonstrated improved optical sectioning in TIRF microscopy (Optics Express, Vol. 24, Issue 26).
![Cover 3D Tracks](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka3_3d_tracks_flipped_vertical.jpeg?h=8844e68f&itok=dwApzr7h)
High-speed particle tracking of clathrin-coated vesicles in 3D. Dean, Kevin M., et al., Biophysical journal 110.6 (2016): 1456-1465.
![Cellin Collagen](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka4_cellin_collagen.jpeg?h=2a479378&itok=Bu3xKlNZ)
Melanoma cell embedded in collagen.
![Spheroid Lung Cancer Cells](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka6_spheroid_lung_cancer_cells.jpeg?h=2a479378&itok=HuHdnrbm)
A tumor spheroid consisting of lung cancer cells. Welf, Erik S., et al. Developmental cell 36.4 (2016): 462-475.
![RPE Vimentin with Bounding Box](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka7_rpe_vimentin_w_bounding.jpeg?h=2a479378&itok=DHSAp4cv)
RPE cells, labeled for vimentin and microtubules, embedded in collagen.
![RPE Vimentin Emerald](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka8_rpe_vimentin_emerald2.jpeg?h=b784dcb1&itok=bnje4Dvo)
RPE cells, labeled for vimentin, embedded in collagen.
![RPE Cells](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka9_rpe_cells.jpeg?h=2a479378&itok=FIkRYi1W)
RPE cells embedded in collagen.
![Porcupine Cell](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka9_porcupine_cell.jpeg?h=4000a949&itok=ow1p8p8W)
Filipodia in a lung cancer cell. Welf, Erik S., et al. Developmental cell 36.4 (2016): 462-475.
![Mito MIP](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka10_mito_mip.jpeg?h=384e2afb&itok=PYjmNhzS)
Mitochondria in a HeLa cell imaged with structured illumination.
![RPE1Htert TractinGFP Cell6 MIP Slice](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka11_max_bleach_corrected_rpe1.jpeg?h=b6ee11f0&itok=wOVMXhmg)
RPE labeled with tractin-GFP embedded in collagen.
![Louis Assembly Render](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka12_louis_assembly_render.jpeg?h=ec12756c&itok=uDo2M1CM)
Louis Assembly Render
![Hela Actin Clathrin](/sites/default/files/styles/gallery_slider/public/2022-06/hela_actin_clathrin.jpeg?h=3ca523da&itok=H1QXBQbp)
Actin cytoskeleton and clathrin coated pits in a HeLa cell imaged with structured illumination.
![Detected Collagen Color Coded](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka14_detected_collagen_color_coded.jpeg?h=eb938651&itok=Ba86y_1_)
Collagen density surrounding a melanoma cell. Welf, Erik S., etal. Developmental cell 36.4 (2016): 462-475.
![Cell in Collagen Cube](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka15_cellin_collagen_cube.jpeg?h=84c3122f&itok=W7to-ZiL)
3D rendering of melanoma cell in collagen. Welf, Erik S., et al. Developmental cell 36.4 (2016): 462-475.
![Cancer Cell Surfaces](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka16_cancer_cell_surfaces_small.jpeg?h=adef4f31&itok=GHwsobLe)
Surface concentration of actin (left) and a biosensor (right) on a lung and melanoma cell, respectively. Welf, Erik S., et al. Developmental cell 36.4 (2016): 462-475.
![Cover Ruffles](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka17_cover_ruffles_small.jpeg?h=8844e68f&itok=g-u3qOPB)
Rapid volumetric imaging with diagonally scanned light sheet microscopy. Dean, Kevin M., et al. Biophysical Journal 110.6 (2016): 1456-1465.
![Actin Hela](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka18_actin_hela.jpeg?h=1bf8d4ad&itok=qimth7bb)
Actin cytoskeleton in a HeLa cell imaged by structured illumination microscopy.
![Blebby Render](/sites/default/files/styles/gallery_slider/public/2022-06/fiolka19_blebby_render.jpeg?h=498b0cf2&itok=G0D2zW1H)
Bleb protruding through collagen network.
![Neurons - Optica](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka1_neurons.jpeg?h=2a479378&itok=xJ9JlPuL)
![Grazing Incidence](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka2_grazing-cell-struct.jpeg?h=1b830d40&itok=yQklbS5t)
![Cover 3D Tracks](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka3_3d_tracks_flipped_vertical.jpeg?h=8844e68f&itok=owkoI8QF)
![Cellin Collagen](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka4_cellin_collagen.jpeg?h=2a479378&itok=xBUdli2g)
![Spheroid Lung Cancer Cells](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka6_spheroid_lung_cancer_cells.jpeg?h=2a479378&itok=uhPtqm0E)
![RPE Vimentin with Bounding Box](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka7_rpe_vimentin_w_bounding.jpeg?h=2a479378&itok=vA_1bk15)
![RPE Vimentin Emerald](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka8_rpe_vimentin_emerald2.jpeg?h=b784dcb1&itok=2WeRI_TX)
![RPE Cells](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka9_rpe_cells.jpeg?h=2a479378&itok=EPwHMjz4)
![Porcupine Cell](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka9_porcupine_cell.jpeg?h=4000a949&itok=l80UdsIc)
![Mito MIP](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka10_mito_mip.jpeg?h=384e2afb&itok=I7DXTwq8)
![RPE1Htert TractinGFP Cell6 MIP Slice](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka11_max_bleach_corrected_rpe1.jpeg?h=b6ee11f0&itok=SJD0eKad)
![Louis Assembly Render](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka12_louis_assembly_render.jpeg?h=ec12756c&itok=OsnOD_MI)
![Hela Actin Clathrin](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/hela_actin_clathrin.jpeg?h=3ca523da&itok=lGapfbUm)
![Detected Collagen Color Coded](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka14_detected_collagen_color_coded.jpeg?h=eb938651&itok=ufAzmAb1)
![Cell in Collagen Cube](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka15_cellin_collagen_cube.jpeg?h=84c3122f&itok=zzEIbUWu)
![Cancer Cell Surfaces](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka16_cancer_cell_surfaces_small.jpeg?h=adef4f31&itok=7hQ-rPYR)
![Cover Ruffles](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka17_cover_ruffles_small.jpeg?h=8844e68f&itok=kjpedAEa)
![Actin Hela](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka18_actin_hela.jpeg?h=1bf8d4ad&itok=kCNJn0i_)
![Blebby Render](/sites/default/files/styles/coh_xx_small_landscape/public/2022-06/fiolka19_blebby_render.jpeg?h=498b0cf2&itok=jrRzcKCl)