We are developing inhibitors of pyrimidine biosynthesis and polyamine biosynthesis to treat malaria and African sleeping sickness.
We study polyamine and nucleotide metabolism in African trypanosomes to learn about novel metabolism and regulation.
Meet the Principal Investigator
Margaret Phillips, Ph.D.
Margaret Phillips, Ph.D., has been a tenured Professor at UT Southwestern Medical Center since 2002, and she is currently Chair of the Department of Biochemistry with a secondary faculty appointment in the Department of Pharmacology. She holds the Sam G. Winstead and F. Andrew Bell Distinguished Chair in Biochemistry. She received her B.S. in biochemistry from the University of California, Davis, in 1981 and her Ph.D. in pharmaceutical chemistry from the University of California, San Francisco, in 1988.
She is currently a Section editor of PLoS Pathogens and serves on the editorial boards of PLoS Neglected Diseases and mShere.
Meet the Team
Get to know our Principal Investigator and team of researchers.See Lab Members & Alumni
We study the parasites that cause malaria and African sleeping sickness.View Our Research
Collaborate with Us
The Phillips Lab collaborates with many researchers to fight protozoan parasites.Get in Touch