Publications

Highlight Publications

Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER.Toulmay A, Whittle FB, Yang J, Bai X, Diarra J, Banerjee S, Levine TP, Golden A, Prinz WA. J Cell Biol. 2022 Mar 7;221(3):e202111095. doi: 10.1083/jcb.202111095. Epub 2022 Jan 11.PMID: 35015055

Retinyl esters form lipid droplets independently of triacylglycerol and seipin.
Molenaar MR*, Yadav KK*, Toulmay A, Wassenaar TA, Mari MC, Caillon L, Chorlay A, Lukmantara IE, Haaker MW, Wubbolts RW, Houweling M, Vaandrager AB, Prieur X, Reggiori F, Choudhary V, Yang H, Schneiter R, Thiam AR, Prinz WA*, Helms JB*. J Cell Biol. 2021 Oct 4;220(10):e202011071. doi: 10.1083/jcb.202011071. Epub 2021 Jul 29.PMID: 34323918

Lipid droplet and peroxisome biogenesis occur at the same ER subdomains.
Joshi AS, Nebenfuehr B, Choudhary V, Satpute-Krishnan P, Levine TP, Golden A, Prinz WA. Nat Commun. 2018 Jul 27;9(1):2940. doi: 10.1038/s41467-018-05277-3.PMID: 30054481

Architecture of Lipid Droplets in Endoplasmic Reticulum Is Determined by Phospholipid Intrinsic Curvature.
Choudhary V, Golani G, Joshi AS, Cottier S, Schneiter R, Prinz WA, Kozlov MM. Curr Biol. 2018 Mar 19;28(6):915-926.e9. doi: 10.1016/j.cub.2018.02.020. Epub 2018 Mar 8.PMID: 29526591

An inducible ER-Golgi tether facilitates ceramide transport to alleviate lipotoxicity.
Liu LK, Choudhary V, Toulmay A, Prinz WA. J Cell Biol. 2017 Jan 2;216(1):131-147. doi: 10.1083/jcb.201606059. Epub 2016 Dec 23.PMID: 28011845

A family of membrane-shaping proteins at ER subdomains regulates pre-peroxisomal vesicle biogenesis.
Joshi AS, Huang X, Choudhary V, Levine TP, Hu J, Prinz WA. J Cell Biol. 2016 Nov 21;215(4):515-529. doi: 10.1083/jcb.201602064. Epub 2016 Nov 8.PMID: 27872254

Full Publications:

2024

Making the connection: How membrane contact sites have changed our view of organelle biology.

Voeltz GK, Sawyer EM, Hajnóczky G, Prinz WA. Cell. 2024 Jan 18;187(2):257-270. doi: 10.1016/j.cell.2023.11.040.

PMID: 38242082

2023

Early steps in the birth of four membrane-bound organelles-Peroxisomes, lipid droplets, lipoproteins, and autophagosomes.

Banerjee S, Prinz WA. Curr Opin Cell Biol. 2023 Oct; 84:102210. doi:10.1016/j.ceb.2023.102210. Epub 2023 Jul 31. PMID: 37531895

2022

Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER.
Toulmay A, Whittle FB, Yang J, Bai X, Diarra J, Banerjee S, Levine TP, Golden A, Prinz WA. J Cell Biol. 2022 Mar 7;221(3):e202111095. doi: 10.1083/jcb.202111095. Epub 2022 Jan 11.PMID: 35015055

2021

Target of Rapamycin Complex 1 (TORC1), Protein Kinase A (PKA) and Cytosolic pH Regulate a Transcriptional Circuit for Lipid Droplet Formation.
Teixeira V, Martins TS, Prinz WA, Costa V. Int J Mol Sci. 2021 Aug 20;22(16):9017. doi: 10.3390/ijms22169017.PMID: 34445723

ESCRTs got your Bac!
Deo RA, Prinz WA. Cell. 2021 Jul 8;184(14):3591-3592. doi: 10.1016/j.cell.2021.06.017.PMID: 34242559

VPS13D promotes peroxisome biogenesis.
Baldwin HA, Wang C, Kanfer G, Shah HV, Velayos-Baeza A, Dulovic-Mahlow M, Brüggemann N, Anding A, Baehrecke EH, Maric D, Prinz WA, Youle RJ. J Cell Biol. 2021 May 3;220(5):e202001188. doi: 10.1083/jcb.202001188.PMID: 33891012

Multiple C2 domain-containing transmembrane proteins promote lipid droplet biogenesis and growth at specialized endoplasmic reticulum subdomains.
Joshi AS, Ragusa JV, Prinz WA, Cohen S. Mol Biol Cell. 2021 Jun 1;32(12):1147-1157. doi: 10.1091/mbc.E20-09-0590. Epub 2021 Apr 7.PMID: 33826368

Mechanisms of nonvesicular lipid transport.
Reinisch KM, Prinz WA. J Cell Biol. 2021 Mar 1;220(3):e202012058. doi: 10.1083/jcb.202012058.PMID: 33605998

Correction: Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response.
Schuck S, Prinz WA, Thorn KS, Voss C, Walter P. J Cell Biol. 2021 Apr 5;220(4):jcb.20090707402092021c. doi: 10.1083/jcb.20090707402092021c.PMID: 33600553

2020

The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis.
Yap WS, Shyu P Jr, Gaspar ML, Jesch SA, Marvalim C, Prinz WA, Henry SA, Thibault G. J Cell Sci. 2020 Nov 5;133(21):jcs248526. doi: 10.1242/jcs.248526.PMID: 33033181

Seipin and Nem1 establish discrete ER subdomains to initiate yeast lipid droplet biogenesis.
Choudhary V, El Atab O, Mizzon G, Prinz WA, Schneiter R. J Cell Biol. 2020 Jul 6;219(7):e201910177. doi: 10.1083/jcb.201910177.PMID: 32349126

A firehose for phospholipids.
Prinz WA, Hurley JH. J Cell Biol. 2020 May 4;219(5):e202003132. doi: 10.1083/jcb.202003132.PMID: 32339216

The functional universe of membrane contact sites.
Prinz WA, Toulmay A, Balla T. Nat Rev Mol Cell Biol. 2020 Jan;21(1):7-24. doi: 10.1038/s41580-019-0180-9. Epub 2019 Nov 15.PMID: 31732717

2018

A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed.
Lin CC, Kurashige M, Liu Y, Terabayashi T, Ishimoto Y, Wang T, Choudhary V, Hobbs R, Liu LK, Lee PH, Outeda P, Zhou F, Restifo NP, Watnick T, Kawano H, Horie S, Prinz W, Xu H, Menezes LF, Germino GG. Sci Rep. 2018 Feb 9;8(1):2743. doi: 10.1038/s41598-018-20856-6.PMID: 29426897

2017

Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes.
Hayes M, Choudhary V, Ojha N, Shin JJ, Han GS, Carman GM, Loewen CJ, Prinz WA, Levine T. Microb Cell. 2017 Dec 28;5(2):88-103. doi: 10.15698/mic2018.02.614.PMID: 29417057

Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER.
Friedman JR, Kannan M, Toulmay A, Jan CH, Weissman JS, Prinz WA, Nunnari J. Dev Cell. 2018 Jan 22;44(2):261-270.e6. doi: 10.1016/j.devcel.2017.11.023. Epub 2017 Dec 28.PMID: 29290583

A cholesterol-sensing mechanism unfolds.
Prinz WA. J Biol Chem. 2017 Dec 8;292(49):19974-19975. doi: 10.1074/jbc.H117.794230.PMID: 29222193

Sequences flanking the transmembrane segments facilitate mitochondrial localization and membrane fusion by mitofusin.
Huang X, Zhou X, Hu X, Joshi AS, Guo X, Zhu Y, Chen Q, Prinz WA, Hu J. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9863-E9872. doi: 10.1073/pnas.1708782114. Epub 2017 Nov 1.PMID: 29093165

Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling.
Murley A, Yamada J, Niles BJ, Toulmay A, Prinz WA, Powers T, Nunnari J. J Cell Biol. 2017 Sep 4;216(9):2679-2689. doi: 10.1083/jcb.201610032. Epub 2017 Aug 3.PMID: 28774891

Organelle biogenesis in the endoplasmic reticulum.
Joshi AS, Zhang H, Prinz WA. Nat Cell Biol. 2017 Aug;19(8):876-882. doi: 10.1038/ncb3579. Epub 2017 Jul 17.PMID: 28714972

Phosphatidylserine synthesis at membrane contact sites promotes its transport out of the ER.
Kannan M, Lahiri S, Liu LK, Choudhary V, Prinz WA. J Lipid Res. 2017 Mar;58(3):553-562. doi: 10.1194/jlr.M072959. Epub 2017 Jan 24.PMID: 28119445

Glycerolipid synthesis and lipid trafficking in plant mitochondria.
Michaud M, Prinz WA, Jouhet J. FEBS J. 2017 Feb;284(3):376-390. doi: 10.1111/febs.13812. Epub 2016 Aug 1.PMID: 27406373

2016

Endoplasmic reticulum stress affects the transport of phosphatidylethanolamine from mitochondria to the endoplasmic reticulum in S.cerevisiae.
Kannan M, Sivaprakasam C, Prinz WA, Nachiappan V. Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):1959-1967. doi: 10.1016/j.bbalip.2016.09.015. Epub 2016 Sep 24.PMID: 27678054

Keeping in shape.
Blackstone C, Prinz WA. Elife. 2016 Sep 13;5:e20468. doi: 10.7554/eLife.20468.PMID: 27619978

Keeping FIT, storing fat: Lipid droplet biogenesis.
Choudhary V, Golden A, Prinz WA. Worm. 2016 Apr 4;5(2):e1170276. doi: 10.1080/21624054.2016.1170276. eCollection 2016 Apr-Jun.PMID: 27383728

AtMic60 Is Involved in Plant Mitochondria Lipid Trafficking and Is Part of a Large Complex.
Michaud M, Gros V, Tardif M, Brugière S, Ferro M, Prinz WA, Toulmay A, Mathur J, Wozny M, Falconet D, Maréchal E, Block MA, Jouhet J. Curr Biol. 2016 Mar 7;26(5):627-39. doi: 10.1016/j.cub.2016.01.011. Epub 2016 Feb 18.PMID: 26898467

2015

A conserved family of proteins facilitates nascent lipid droplet budding from the ER.
Choudhary V, Ojha N, Golden A, Prinz WA. J Cell Biol. 2015 Oct 26;211(2):261-71. doi: 10.1083/jcb.201505067.PMID: 26504167

Ltc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts.
Murley A, Sarsam RD, Toulmay A, Yamada J, Prinz WA, Nunnari J. J Cell Biol. 2015 May 25;209(4):539-48. doi: 10.1083/jcb.201502033. Epub 2015 May 18.PMID: 25987606

Form follows function: the importance of endoplasmic reticulum shape.
Westrate LM, Lee JE, Prinz WA, Voeltz GK. Annu Rev Biochem. 2015;84:791-811. doi: 10.1146/annurev-biochem-072711-163501. Epub 2015 Jan 12.PMID: 25580528

2014

Membrane contact sites, gateways for lipid homeostasis.
Lahiri S, Toulmay A, Prinz WA. Curr Opin Cell Biol. 2015 Apr;33:82-87. doi: 10.1016/j.ceb.2014.12.004. Epub 2015 Jan 6.PMID: 25569848

A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria.
Lahiri S, Chao JT, Tavassoli S, Wong AK, Choudhary V, Young BP, Loewen CJ, Prinz WA. PLoS Biol. 2014 Oct 14;12(10):e1001969. doi: 10.1371/journal.pbio.1001969. eCollection 2014 Oct.PMID: 25313861

Bridging the gap: membrane contact sites in signaling, metabolism, and organelle dynamics.
Prinz WA. J Cell Biol. 2014 Jun 23;205(6):759-69. doi: 10.1083/jcb.201401126.PMID: 24958771

The lipid trade.
Prinz WA. Nat Rev Mol Cell Biol. 2014 Feb;15(2):79. doi: 10.1038/nrm3740. Epub 2014 Jan 17.PMID: 24434885

2013

Direct imaging reveals stable, micrometer-scale lipid domains that segregate proteins in live cells.
Toulmay A, Prinz WA. J Cell Biol. 2013 Jul 8;202(1):35-44. doi: 10.1083/jcb.201301039.PMID: 23836928

Plasma membrane-endoplasmic reticulum contact sites regulate phosphatidylcholine synthesis.
Tavassoli S, Chao JT, Young BP, Cox RC, Prinz WA, de Kroon AI, Loewen CJ. EMBO Rep. 2013 May;14(5):434-40. doi: 10.1038/embor.2013.36. Epub 2013 Mar 22.PMID: 23519169

A bridge to understanding lipid droplet growth.
Prinz WA. Dev Cell. 2013 Feb 25;24(4):335-6. doi: 10.1016/j.devcel.2013.02.004.PMID: 23449466

2012

Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion.
Liu TY, Bian X, Sun S, Hu X, Klemm RW, Prinz WA, Rapoport TA, Hu J. Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):E2146-54. doi: 10.1073/pnas.1208385109. Epub 2012 Jul 16.PMID: 22802620

ER-shaping proteins facilitate lipid exchange between the ER and mitochondria in S. cerevisiae.
Voss C, Lahiri S, Young BP, Loewen CJ, Prinz WA. J Cell Sci. 2012 Oct 15;125(Pt 20):4791-9. doi: 10.1242/jcs.105635. Epub 2012 Jul 13.PMID: 22797914

The budding yeast nuclear envelope adjacent to the nucleolus serves as a membrane sink during mitotic delay.
Witkin KL, Chong Y, Shao S, Webster MT, Lahiri S, Walters AD, Lee B, Koh JL, Prinz WA, Andrews BJ, Cohen-Fix O. Curr Biol. 2012 Jun 19;22(12):1128-33. doi: 10.1016/j.cub.2012.04.022. Epub 2012 May 31.PMID: 22658600

The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae.
Anwar K, Klemm RW, Condon A, Severin KN, Zhang M, Ghirlando R, Hu J, Rapoport TA, Prinz WA. J Cell Biol. 2012 Apr 16;197(2):209-17. doi: 10.1083/jcb.201111115.PMID: 22508509

A conserved membrane-binding domain targets proteins to organelle contact sites.
Toulmay A, Prinz WA. J Cell Sci. 2012 Jan 1;125(Pt 1):49-58. doi: 10.1242/jcs.085118. Epub 2012 Jan 16.PMID: 22250200

2011

Weaving the web of ER tubules.
Hu J, Prinz WA, Rapoport TA. Cell. 2011 Dec 9;147(6):1226-31. doi: 10.1016/j.cell.2011.11.022.PMID: 22153070

Lipid transfer and signaling at organelle contact sites: the tip of the iceberg.
Toulmay A, Prinz WA. Curr Opin Cell Biol. 2011 Aug;23(4):458-63. doi: 10.1016/j.ceb.2011.04.006.PMID: 21555211

A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking.
Du X, Kumar J, Ferguson C, Schulz TA, Ong YS, Hong W, Prinz WA, Parton RG, Brown AJ, Yang H. J Cell Biol. 2011 Jan 10;192(1):121-35. doi: 10.1083/jcb.201004142.PMID: 21220512

2000-2010

Lipid trafficking sans vesicles: where, why, how?
Prinz WA. Cell. 2010 Dec 10;143(6):870-4. doi: 10.1016/j.cell.2010.11.031.PMID: 21145454

Mechanisms determining the morphology of the peripheral ER.
Shibata Y, Shemesh T, Prinz WA, Palazzo AF, Kozlov MM, Rapoport TA. Cell. 2010 Nov 24;143(5):774-88. doi: 10.1016/j.cell.2010.11.007.PMID: 21111237

Phosphatidylserine is involved in the ferrichrome-induced plasma membrane trafficking of Arn1 in Saccharomyces cerevisiae.
Guo Y, Au WC, Shakoury-Elizeh M, Protchenko O, Basrai M, Prinz WA, Philpott CC. J Biol Chem. 2010 Dec 10;285(50):39564-73. doi: 10.1074/jbc.M110.177055. Epub 2010 Oct 5.PMID: 20923770

Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism.
Young BP, Shin JJ, Orij R, Chao JT, Li SC, Guan XL, Khong A, Jan E, Wenk MR, Prinz WA, Smits GJ, Loewen CJ. Science. 2010 Aug 27;329(5995):1085-8. doi: 10.1126/science.1191026.PMID: 20798321

Metabolic response to iron deficiency in Saccharomyces cerevisiae.
Shakoury-Elizeh M, Protchenko O, Berger A, Cox J, Gable K, Dunn TM, Prinz WA, Bard M, Philpott CC. J Biol Chem. 2010 May 7;285(19):14823-33. doi: 10.1074/jbc.M109.091710. Epub 2010 Mar 15.PMID: 20231268

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues.
Schulz TA, Choi MG, Raychaudhuri S, Mears JA, Ghirlando R, Hinshaw JE, Prinz WA.J Cell Biol. 2009 Dec 14;187(6):889-903. doi: 10.1083/jcb.200905007.PMID: 20008566 Free PMC article.

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response.
Schuck S, Prinz WA, Thorn KS, Voss C, Walter P. J Cell Biol. 2009 Nov 16;187(4):525-36. doi: 10.1083/jcb.200907074. Epub 2009 Nov 9.PMID: 19948500

Membrane-bending proteins.
Prinz WA, Hinshaw JE. Crit Rev Biochem Mol Biol. 2009 Sep-Oct;44(5):278-91. doi: 10.1080/10409230903183472.PMID: 19780639

A class of dynamin-like GTPases involved in the generation of the tubular ER network.
Hu J, Shibata Y, Zhu PP, Voss C, Rismanchi N, Prinz WA, Rapoport TA, Blackstone C. Cell. 2009 Aug 7;138(3):549-61. doi: 10.1016/j.cell.2009.05.025.PMID: 19665976

The diverse functions of oxysterol-binding proteins.
Raychaudhuri S, Prinz WA. Annu Rev Cell Dev Biol. 2010;26:157-77. doi: 10.1146/annurev.cellbio.042308.113334.PMID: 19575662

Control of protein and sterol trafficking by antagonistic activities of a type IV P-type ATPase and oxysterol binding protein homologue.
Muthusamy BP, Raychaudhuri S, Natarajan P, Abe F, Liu K, Prinz WA, Graham TR. Mol Biol Cell. 2009 Jun;20(12):2920-31. doi: 10.1091/mbc.e08-10-1036. Epub 2009 Apr 29.PMID: 19403696

Calmodulin-driven nuclear entry: trigger for sex determination and terminal differentiation.
Hanover JA, Love DC, Prinz WA. J Biol Chem. 2009 May 8;284(19):12593-7. doi: 10.1074/jbc.R800076200. Epub 2009 Jan 5.PMID: 19126540

Nonvesicular phospholipid transfer between peroxisomes and the endoplasmic reticulum.
Raychaudhuri S, Prinz WA.Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15785-90. doi: 10.1073/pnas.0808321105. Epub 2008 Oct 3.PMID: 18836080

Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae.
Federovitch CM, Jones YZ, Tong AH, Boone C, Prinz WA, Hampton RY. Mol Biol Cell. 2008 Oct;19(10):4506-20. doi: 10.1091/mbc.e07-11-1188. Epub 2008 Jul 30.PMID: 18667535

The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum.
Shibata Y, Voss C, Rist JM, Hu J, Rapoport TA, Prinz WA, Voeltz GK. J Biol Chem. 2008 Jul 4;283(27):18892-904. doi: 10.1074/jbc.M800986200. Epub 2008 Apr 28.PMID: 18442980

Dynamics of cholesterol exchange in the oxysterol binding protein family.
Canagarajah BJ, Hummer G, Prinz WA, Hurley JH. J Mol Biol. 2008 May 2;378(3):737-48. doi: 10.1016/j.jmb.2008.01.075. Epub 2008 Feb 4.PMID: 18377932

Membrane proteins of the endoplasmic reticulum induce high-curvature tubules.
Hu J, Shibata Y, Voss C, Shemesh T, Li Z, Coughlin M, Kozlov MM, Rapoport TA, Prinz WA. Science. 2008 Feb 29;319(5867):1247-50. doi: 10.1126/science.1153634.PMID: 18309084

The High Mobility Group Box Transcription Factor Nhp6Ap enters the nucleus by a calmodulin-dependent, Ran-independent pathway.
Hanover JA, Love DC, DeAngelis N, O'Kane ME, Lima-Miranda R, Schulz T, Yen YM, Johnson RC, Prinz WA. J Biol Chem. 2007 Nov 16;282(46):33743-33751. doi: 10.1074/jbc.M705875200. Epub 2007 Sep 18.PMID: 17878171

Non-vesicular sterol transport in cells.
Prinz WA. Prog Lipid Res. 2007 Nov;46(6):297-314. doi: 10.1016/j.plipres.2007.06.002. Epub 2007 Jul 18.PMID: 17709145

Sterol transport in yeast and the oxysterol binding protein homologue (OSH) family.
Schulz TA, Prinz WA. Biochim Biophys Acta. 2007 Jun;1771(6):769-80. doi: 10.1016/j.bbalip.2007.03.003. Epub 2007 Mar 16.PMID: 17434796

Sheets, ribbons and tubules - how organelles get their shape.
Voeltz GK, Prinz WA. Nat Rev Mol Cell Biol. 2007 Mar;8(3):258-64. doi: 10.1038/nrm2119. Epub 2007 Feb 7.PMID: 17287811

Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer.
Forsythe ME, Love DC, Lazarus BD, Kim EJ, Prinz WA, Ashwell G, Krause MW, Hanover JA. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11952-7. doi: 10.1073/pnas.0601931103. Epub 2006 Aug 1.PMID: 16882729

Uptake and trafficking of exogenous sterols in Saccharomyces cerevisiae.
Raychaudhuri S, Prinz WA. Biochem Soc Trans. 2006 Jun;34(Pt 3):359-62. doi: 10.1042/BST0340359.PMID: 16709161

Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides.
Raychaudhuri S, Im YJ, Hurley JH, Prinz WA. J Cell Biol. 2006 Apr 10;173(1):107-19. doi: 10.1083/jcb.200510084. Epub 2006 Apr 3.PMID: 16585271

A class of membrane proteins shaping the tubular endoplasmic reticulum.
Voeltz GK, Prinz WA, Shibata Y, Rist JM, Rapoport TA. Cell. 2006 Feb 10;124(3):573-86. doi: 10.1016/j.cell.2005.11.047.PMID: 16469703

Structural mechanism for sterol sensing and transport by OSBP-related proteins.
Im YJ, Raychaudhuri S, Prinz WA, Hurley JH. Nature. 2005 Sep 1;437(7055):154-8. doi: 10.1038/nature03923.PMID: 16136145

ATP-binding cassette (ABC) transporters mediate nonvesicular, raft-modulated sterol movement from the plasma membrane to the endoplasmic reticulum.
Li Y, Prinz WA. J Biol Chem. 2004 Oct 22;279(43):45226-34. doi: 10.1074/jbc.M407600200. Epub 2004 Aug 16.PMID: 15316012

Cholesterol trafficking in the secretory and endocytic systems.
Prinz W. Semin Cell Dev Biol. 2002 Jun;13(3):197-203. doi: 10.1016/s1084-9521(02)00048-4.PMID: 12137740

Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae.
Prinz WA, Grzyb L, Veenhuis M, Kahana JA, Silver PA, Rapoport TA. J Cell Biol. 2000 Aug 7;150(3):461-74. doi: 10.1083/jcb.150.3.461.PMID: 10931860

Determinants of translocation and folding of TreF, a trehalase of Escherichia coli.
Uhland K, Mondigler M, Spiess C, Prinz W, Ehrmann M. J Biol Chem. 2000 Aug 4;275(31):23439-45. doi: 10.1074/jbc.M002793200.PMID: 10816581

1990-1999

The protein translocation apparatus contributes to determining the topology of an integral membrane protein in Escherichia coli.
Prinz WA, Boyd DH, Ehrmann M, Beckwith J. J Biol Chem. 1998 Apr 3;273(14):8419-24. doi: 10.1074/jbc.273.14.8419.PMID: 9525953

Protein translocation in the three domains of life: variations on a theme.
Pohlschröder M, Prinz WA, Hartmann E, Beckwith J. Cell. 1997 Nov 28;91(5):563-6. doi: 10.1016/s0092-8674(00)80443-2.PMID: 9393849

The role of the thioredoxin and glutaredoxin pathways in reducing protein disulfide bonds in the Escherichia coli cytoplasm.
Prinz WA, Aslund F, Holmgren A, Beckwith J. J Biol Chem. 1997 Jun 20;272(25):15661-7. doi: 10.1074/jbc.272.25.15661.PMID: 9188456

Targeting of signal sequenceless proteins for export in Escherichia coli with altered protein translocase.
Prinz WA, Spiess C, Ehrmann M, Schierle C, Beckwith J. EMBO J. 1996 Oct 1;15(19):5209-17.PMID: 8895566

Essential features of the pathway for protein translocation across the Escherichia coli cytoplasmic membrane.
Murphy C, Prinz W, Pohlschröder M, Derman A, Beckwith J. Cold Spring Harb Symp Quant Biol. 1995;60:277-83. doi: 10.1101/sqb.1995.060.01.032.PMID: 8824401

Gene fusion analysis of membrane protein topology: a direct comparison of alkaline phosphatase and beta-lactamase fusions.
Prinz WA, Beckwith J. J Bacteriol. 1994 Oct;176(20):6410-3. doi: 10.1128/jb.176.20.6410-6413.1994.PMID: 7929016

Mutations that allow disulfide bond formation in the cytoplasm of Escherichia coli.
Derman AI, Prinz WA, Belin D, Beckwith J. Science. 1993 Dec 10;262(5140):1744-7. doi: 10.1126/science.8259521.PMID: 8259521

Gene fusion approaches to membrane protein topology.
Boyd D, Traxler B, Jander G, Prinz W, Beckwith J. Soc Gen Physiol Ser. 1993;48:23-37.PMID: 8503047

Mutation of monofunctional 6-phosphofructo-2-kinase in yeast to bifunctional 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase.
Kretschmer M, Langer C, Prinz W. Biochemistry. 1993 Oct 19;32(41):11143-8. doi: 10.1021/bi00092a025.PMID: 8218176

Pre-90's

Regional changes in adipose tissue blood flow and metabolism in rats after a meal.
West DB, Prinz WA, Greenwood MR. Am J Physiol. 1989 Oct;257(4 Pt 2):R711-6. doi: 10.1152/ajpregu.1989.257.4.R711.PMID: 2679149

Adipocyte blood flow is decreased in obese Zucker rats.
West DB, Prinz WA, Francendese AA, Greenwood MR. Am J Physiol. 1987 Aug;253(2 Pt 2):R228-33. doi: 10.1152/ajpregu.1987.253.2.R228.PMID: 3618823

Human alpha-interferon enhances in vitro IgM rheumatoid factor synthesis by lymphocytes from normal subjects and rheumatoid arthritis patients.
Rodriguez MA, Prinz WA, Sibbitt WL, Bankhurst AD, Williams RC Jr. Arthritis Rheum. 1983 Sep;26(9):1091-7. doi: 10.1002/art.1780260906.PMID: 6311224

alpha-Interferon increases immunoglobulin production in cultured human mononuclear leukocytes.
Rodriguez MA, Prinz WA, Sibbitt WL, Bankhurst AD, Williams RC Jr. sJ Immunol. 1983 Mar;130(3):1215-9.PMID: 6296232