People

Current Lab Members

a man with short hair, beard and mustache wearing a white lab coat

Kartik Rajagopalan, M.D., Ph.D.

Position: Principal Investigator  |  Email Dr. Rajagopalan

 

Dr. Kartik Rajagopalan is a physician-scientist and Assistant Professor in the Department of Internal Medicine, and a member of the Division of Pulmonary and Critical Care Medicine at UT Southwestern. He specializes in medical critical care.

Dr. Rajagopalan earned his medical and doctoral degrees at UT Southwestern where he studied metabolic fluxes during cell proliferation in the lab of Dr. Ralph DeBerardinis. He then completed his Internal Medicine Residency and Pulmonary and Critical-care Fellowship at Columbia University in New York. He performed post-doctoral work understanding the role of leptin signaling during influenza and COVID infection in the lab of Dr. Jeffrey Friedman at Rockefeller University. 

He returned to UT Southwestern to start a faculty position and laboratory in September of 2023.

When not in the laboratory, Kartik continues to practice medicine as an intensivist.

Tadiwanashe Gwatiringa with dark hair wearing a tan sweater stainding in a laboratory environment

Tadiwanashe Gwatiringa

Position: Research Assistant/Lab Manager | Email Tadiwanashe

 

With a solid academic foundation and a visionary approach to health and society, Tadiwanashe is on a trajectory towards making a substantial impact in the medical field.

Tadiwanashe holds a bachelor's degree in human biology, health, and society from Cornell University in Ithaca, New York.

She is on a pre-med academic track to pursue a combined MD/PhD which she intends to use to deepen her knowledge and understanding of health disparities, with the goal of devising strategies that contribute significantly to improving healthcare access and outcomes for underserved communities.

David Bautista wearing a tan hoodie standing in a research laboratory

David Bautista, Ph.D.

Position: Postdoctoral Researcher | Email David

 

Dr. David Bautista is from San Antonio, Texas and he earned his Bachelor of Science in Biomedical Sciences from Texas A&M University – Kingsville. He discovered his passion for research as an undergraduate student by conducting research on potassium channels in Drosophila Melanogaster. This experience led him to a Post Baccalaureate research program at Brown University where he studied the effects of alcohol on brain lipids. Dr. Bautista earned his PhD in Microbiology from Texas A&M University where he studied the relationship between inhibition of DNA Mismatch Repair and increased antibiotic resistance in gram – negative bacteria.

His genuine curiosity and eagerness to learn led him to a post-doctoral position in the department of internal medicine at UT Southwestern. Dr. Bautista’s research focuses on the role of the hormone Leptin, and the potential it has for therapeutic strategies during chronic infection.

Shang Kui Xie wearing a blue hoodie standing in a laboratory

Shang Kui Xie

Position: Research Scientist | Email Shang

Shangkui Xie has worked in UTSW for more than 20 years, involving in the studies of autoimmune diseases (systemic lupus erythematosus), metabolic disorders including diabetes, and cystic fibrosis by using different mouse models carrying genetic related genes or locus/loci in specific chromosomes.

Shangkui loves to work together with colleagues by using expertise knowledge and skills including PCR/qPCR/ sequencing to take care of large cohorts of mice with specific genetic backgrounds and phenotypes. He is good at rodent handling and is familiar with rodent challenging approaches, including intravenous injection / gavage, etc. He has excellent surgical skills to set up cannulation system in mice and rats, by using jugular vein, carotid artery, portal vein, brain ventricles, etc, for survival study.