The Rohatgi lab focuses on understanding the associations of HDL-related markers to atherosclerotic cardiovascular disease and other phenotypes. These investigations involve assessment of multiple parameters related to HDL, including
- cholesterol concentrations
- particle size and number
- protein levels
- associated functions
Typically, we use the Dallas Heart Study and other large cohorts to refine how these parameters associate with various clinical phenotypes, especially with respect to gender, race/ethnicity, and cardiometabolic status. The analyses are primarily led by trainees and conducted by a population science statistician and database manager affiliated with the Dallas Heart Study. These efforts are supported by internal support, AHA funding, and NHLBI K24.