Publications

Down-regulation of human DAB2IP Gene Expression in Renal Cell Carcinoma Results in Resistance to Ionizing Radiation.

Yun EJ, Lin CJ, Dang A, Hernandez E, Guo J, Chen WM, Allison J, Kim N, Kapur P, Brugarolas J, Wu K, He D, Lai CH, Lin H, Saha D, Baek ST, Chen BPC, Hsieh JT, 2019 Apr Clin. Cancer Res.

The effect of flow on blood oxygen level dependent (R* 2 ) MRI of orthotopic lung tumors.

Zhou H, Belzile O, Zhang Z, Wagner J, Ahn C, Richardson JA, Saha D, Brekken RA, Mason RP 2019 Magn Reson Med 6 81 3787-3797

Tumor-treating fields elicit a conditional vulnerability to ionizing radiation via the downregulation of BRCA1 signaling and reduced DNA double-strand break repair capacity in non-small cell lung cancer cell lines.

Karanam NK, Srinivasan K, Ding L, Sishc B, Saha D, Story MD 2017 Mar Cell Death Dis 3 8 e2711

Tumor physiological changes during hypofractionated stereotactic body radiation therapy assessed using multi-parametric magnetic resonance imaging.

Zhou H, Zhang Z, Denney R, Williams JS, Gerberich J, Stojadinovic S, Saha D, Shelton JM, Mason RP 2017 Mar Oncotarget

EGFR Mutations Compromise Hypoxia-associated Radiation Resistance Through Impaired Replication Fork-associated DNA Damage Repair.

Saki M, Makino H, Javvadi P, Tomimatsu N, Ding L, Clark JE, Gavin E, Takeda K, Andrews J, Saha D, Story MD, Burma S, Nirodi C 2017 Aug Mol. Cancer Res.

Dual-Drug Containing Core-Shell Nanoparticles for Lung Cancer Therapy

Menon J, Kuriakose A, Iyer R, Hernandez E, Gandee L, Zhang S, Takahashi M, Zhang Z, Saha D, Nguyen K 2017 Sci Rep 7 1 13249

Effective Rat Lung Tumor Model for Stereotactic Body Radiation Therapy.

Zhang Z, Wodzak M, Belzile O, Zhou H, Sishc B, Yan H, Stojadinovic S, Mason RP, Brekken RA, Chopra R, Story MD, Timmerman R, Saha D 2016 May Radiat. Res.

Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments.

Yu L, Shang ZF, Abdisalaam S, Lee KJ, Gupta A, Hsieh JT, Asaithamby A, Chen BP, Saha D 2016 Aug Nucleic Acids Res.

Pretreatment biopsy analysis of DAB2IP identifies subpopulation of high-risk prostate cancer patients with worse survival following radiation therapy.

Jacobs C, Tumati V, Kapur P, Yan J, Xie XJ, Hannan R, Hsieh JT, Kim DW, Saha D 2015 Oct Cancer Med

[(68) Ga]-HP-DO3A-nitroimidazole: a promising agent for PET detection of tumor hypoxia.

Wu Y, Hao G, Ramezani S, Saha D, Zhao D, Sun X, Sherry AD 2015 Jun Contrast Media Mol Imaging

NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor.

Yu L, Shang ZF, Hsu FM, Zhang Z, Tumati V, Lin YF, Chen BP, Saha D 2015 Jan Oncotarget

The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry.

Lee KJ, Shang ZF, Lin YF, Sun J, Morotomi-Yano K, Saha D, Chen BP 2015 Apr Neoplasia 4 17 329-38

Reciprocal regulation of hypoxia-inducible factor 2a and GLI1 expression associated with the radioresistance of renal cell carcinoma.

Zhou J, Wu K, Gao D, Zhu G, Wu D, Wang X, Chen Y, Du Y, Song W, Ma Z, Authement C, Saha D, Hsieh JT, He D 2014 Nov Int. J. Radiat. Oncol. Biol. Phys. 4 90 942-51

DOC-2/DAB2 Interacting Protein Status in High-Risk Prostate Cancer Correlates With Outcome for Patients Treated With Radiation Therapy.

Jacobs C, Tumati V, Kapur P, Yan J, Hong D, Bhuiyan M, Xie XJ, Pistenmaa D, Yu L, Hsieh JT, Saha D, Kim DW 2014 May Int. J. Radiat. Oncol. Biol. Phys.

Sensitization of radio-resistant prostate cancer cells with a unique cytolethal distending toxin.

Lai CH, Chang CS, Liu HH, Tsai YS, Hsu FM, Yu YL, Lai CK, Gandee L, Pong RC, Hsu HW, Yu L, Saha D, Hsieh JT 2014 Jun Oncotarget

Polymeric nanoparticles for targeted radiosensitization of prostate cancer cells.

Menon JU, Tumati V, Hsieh JT, Nguyen KT, Saha D 2014 Aug J Biomed Mater Res A

An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIII.

Li L, Chakraborty S, Yang CR, Hatanpaa KJ, Cipher DJ, Puliyappadamba VT, Rehman A, Jiwani AJ, Mickey B, Madden C, Raisanen J, Burma S, Saha D, Wang Z, Pingle SC, Kesari S, Boothman DA, Habib AA 2013 Sep Oncogene

Development of a locally advanced orthotopic prostate tumor model in rats for assessment of combined modality therapy.

Tumati V, Mathur S, Song K, Hsieh JT, Zhao D, Takahashi M, Dobin T, Gandee L, Solberg TD, Habib AA, Saha D 2013 Mar Int. J. Oncol.

Effect of PF-02341066 and radiation on non-small cell lung cancer cells.

Tumati V, Kumar S, Yu L, Chen B, Choy H, Saha D 2013 Mar Oncol. Rep. 3 29 1094-100

EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.

Li L, Puliyappadamba VT, Chakraborty S, Rehman A, Vemireddy V, Saha D, Souza RF, Hatanpaa KJ, Koduru P, Burma S, Boothman DA, Habib AA 2013 Dec Oncogene

Role of p53, Bax, p21, and DNA-PKcs in radiation sensitivity of HCT-116 cells and xenografts.

Huerta S, Gao X, Dineen S, Kapur P, Saha D, Meyer J 2013 Aug Surgery 2 154 143-51

AZD5438, an inhibitor of Cdk1, 2, and 9, enhances the radiosensitivity of non-small cell lung carcinoma cells.

Raghavan P, Tumati V, Yu L, Chan N, Tomimatsu N, Burma S, Bristow RG, Saha D 2012 Nov Int. J. Radiat. Oncol. Biol. Phys. 4 84 e507-14

DAB2IP regulates autophagy in prostate cancer in response to combined treatment of radiation and a DNA-PKcs inhibitor.

Yu L, Tumati V, Tseng SF, Hsu FM, Kim DN, Hong D, Hsieh JT, Jacobs C, Kapur P, Saha D 2012 Dec Neoplasia 12 14 1203-12

Dosimetric characterization of an image-guided stereotactic small animal irradiator.

Pidikiti R, Stojadinovic S, Speiser M, Song KH, Hager F, Saha D, Solberg TD 2011 Apr Phys Med Biol 8 56 2585-99

Murine orthotopic model for the assessment of chemoradiotherapeutic interventions in rectal cancer.

Huerta S, Gao X, Saha D 2011 Apr Anticancer Drugs 4 22 371-6

In vivo bioluminescence imaging of tumor hypoxia dynamics of breast cancer brain metastasis in a mouse model.

Saha D, Dunn H, Zhou H, Harada H, Hiraoka M, Mason RP, Zhao D 2011 J Vis Exp 56

Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks.

Camacho CV, Mukherjee B, McEllin B, Ding LH, Hu B, Habib AA, Xie XJ, Nirodi CS, Saha D, Story MD, Balajee AS, Bachoo RM, Boothman DA, Burma S 2010 Oct Carcinogenesis 10 31 1889-96

Tissue microarray constructs to predict a response to chemoradiation in rectal cancer.

Huerta S, Hrom J, Gao X, Saha D, Anthony T, Reinhart H, Kapur P 2010 Oct Dig Liver Dis 10 42 679-84

Epothilone B confers radiation dose enhancement in DAB2IP gene knock-down radioresistant prostate cancer cells.

Kong Z, Raghavan P, Xie D, Boike T, Burma S, Chen D, Chakraborty A, Hsieh JT, Saha D 2010 Nov Int. J. Radiat. Oncol. Biol. Phys. 4 78 1210-8

An x-ray image guidance system for small animal stereotactic irradiation.

Song KH, Pidikiti R, Stojadinovic S, Speiser M, Seliounine S, Saha D, Solberg TD 2010 Dec Phys Med Biol 23 55 7345-62

Downregulation of human DAB2IP gene expression in prostate cancer cells results in resistance to ionizing radiation.

Kong Z, Xie D, Boike T, Raghavan P, Burma S, Chen DJ, Habib AA, Chakraborty A, Hsieh JT, Saha D 2010 Apr Cancer Res. 7 70 2829-39

Publications for Debabrata Saha, Ph.D.