Seplyarskiy lab at UTSW develops methods and theory to better understand origin and consequences of mutations in DNA
- Mechanisms of germline and somatic mutagenesis
- Deciphering functional effect of mutations using genetic variation in human populations and data somatic tissues
- Quantifying role of de novo mutations in rare monogenic diseases
Meet the Team
Vladimir Seplyarskiy
Assistant Professor
Eugene McDermott Center and Lyda Hill Department of Bioinformatics
Endowed Scholar
Vladimir is interest in mechanisms of mutagenesis, population genetics and Mendelian genomics
email: Vladimir.Seplyarskiy[at]UTSouthwestern.edu
Remus Stana
Postdoctoral Research Fellow
Eugene McDermott Center and Lyda Hill Department of Bioinformatics
email: Remus-Laurentiu.Stana[at]UTSouthwestern.edu
Recent News & Discoveries
03 November 2025
Remus has joined the lab as a postdoc!
08 October 2025
Our paper on clonal expansions in spermatogonia has been published in Nature.
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