Publications

Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity.

Nascentes Melo LM, Sabatier M, Ramesh V, Szylo KJ, Fraser CS, Pon A, Mitchell EC, Servage KA, Allies G, Westedt IV, Cansiz F, Krystkiewicz J, Kutritz A, Schadendorf D, Morrison SJ, Ubellacker JM, Sreelatha A, Tasdogan A, 2024 Dec Cancer Res

Utilizing Thermal Shift Assay to Probe Substrate Binding to Selenoprotein O.

Gonzalez A, Sreelatha A, 2024 Aug J Vis Exp 210

Emerging functions of pseudoenzymes.

Goldberg T, Sreelatha A, 2023 May Biochem J 10 480 715-728

Redefining pseudokinases: A look at the untapped enzymatic potential of pseudokinases.

Pon A, Osinski A, Sreelatha A, 2023 Apr IUBMB Life 4 75 370-376

Identification of selenoprotein O substrates using a biotinylated ATP analog.

Mukherjee M, Sreelatha A, 2022 Methods Enzymol 662 275-296

A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity.

Lopez VA, Park BC, Nowak D, Sreelatha A, Zembek P, Fernandez J, Servage KA, Gradowski M, Hennig J, Tomchick DR, Pawlowski K, Krzymowska M, Tagliabracci VS, 2019 Sep Cell 1 179 205-218.e21

Protein AMPylation by an Evolutionarily Conserved Pseudokinase.

Sreelatha A, Yee SS, Lopez VA, Park BC, Kinch LN, Pilch S, Servage KA, Zhang J, Jiou J, Karasiewicz-Urbanska M, Lobocka M, Grishin NV, Orth K, Kucharczyk R, Pawlowski K, Tomchick DR, Tagliabracci VS, 2018 10 Cell 3 175 809-821.e19

Phosphorylation of spore coat proteins by a family of atypical protein kinases.

Nguyen KB, Sreelatha A, Durrant ES, Lopez-Garrido J, Muszewska A, Dudkiewicz M, Grynberg M, Yee S, Pogliano K, Tomchick DR, Pawlowski K, Dixon JE, Tagliabracci VS, 2016 06 Proc. Natl. Acad. Sci. U.S.A. 25 113 E3482-91

The secretory pathway kinases.

Sreelatha A, Kinch LN, Tagliabracci VS, 2015 Oct Biochim. Biophys. Acta 10 Pt B 1854 1687-93

Vibrio effector protein VopQ inhibits fusion of V-ATPase-containing membranes.

Sreelatha A, Bennett TL, Carpinone EM, O'Brien KM, Jordan KD, Burdette DL, Orth K, Starai VJ, 2015 Jan Proc. Natl. Acad. Sci. U.S.A. 1 112 100-5

Inhibiting AMPylation: a novel screen to identify the first small molecule inhibitors of protein AMPylation.

Lewallen DM, Sreelatha A, Dharmarajan V, Madoux F, Chase P, Griffin PR, Orth K, Hodder P, Thompson PR, 2014 Feb ACS Chem. Biol. 2 9 433-42

Amyloidogenic peptide/single-walled carbon nanotube composites based on tau-protein-related peptides derived from AcPHF6: preparation and dispersive properties.

Muñoz E, Sreelatha A, Garriga R, Baughman RH, Goux WJ, 2013 Jun J Phys Chem B 25 117 7593-604

Vibrio effector protein, VopQ, forms a lysosomal gated channel that disrupts host ion homeostasis and autophagic flux.

Sreelatha A, Bennett TL, Zheng H, Jiang QX, Orth K, Starai VJ, 2013 Jul Proc. Natl. Acad. Sci. U.S.A. 28 110 11559-64

The pore-forming bacterial effector, VopQ, halts autophagic turnover.

Sreelatha A, Orth K, Starai VJ, 2013 Dec Autophagy 12 9 2169-70

Manipulation of host membranes by bacterial effectors.

Ham H, Sreelatha A, Orth K, 2011 Jul Nat. Rev. Microbiol. 9 9 635-46