The Luo lab studies hypoxia stress in human cancers with a focus on epigenetic and metabolic alterations. 

The Reddy Lab focuses on restoring effective antigen presentation to enhance anti-tumor immunity in breast cancers.

Our mission is to improve the care of breast cancer patients through cutting-edge translational research at the interface of clinical oncology, cancer biology, molecular genetics, and translational genomics.

Our lab currently studies hypoxia, prolyl hydroxylase, and VHL signaling in cancer, especially breast and renal cell carcinomas.

My lab has a long-time interest in understanding the mechanisms of transcription and gene regulation in mammalian cells using initially cell-free systems reconstituted with purified gene-specific transcription factors, general cofactors, and components of the general transcription machinery to recapitulate transcriptional events in vitro.