The Ruan Lab focuses its research on developing statistical methods and computational algorithms for multi-omics data with applications in complex human diseases.

How do cells sense metabolites to drive their growth and proliferation?  We seek to study metabolites not only as nutrients but as cellular instruction signals that dictate cell biology. 

The Tu Lab is investigating how a variety of cellular processes and decisions are coordinated with metabolic state, and how the dysregulation of these mechanisms might be linked to disease and aging.

Zaki Lab's research focuses on the the study of gastrointestinal inflammation and cancer.

The McFadden lab uses genetically engineered mice and human cancer cells to identify new genes and small molecules that regulate cancer cell growth.

The Jiang lab studies fundamental mechanisms governing how diverse cell types are generated from naive progenitor cells and how cells of different types are put together to form appropriate body structures such as limbs during embryonic development. The lab also studies how damaged cells are replenished by stem cells during tissue repair and organ regeneration in adult life. We are particularly interested in understanding how cells communicate with one another to influence their growth and fate determination and how miscommunication among different cells leads to developmental abnormality and cancer progression.

D'Orso Lab studies gene regulatory networks in normal and disease states as well as in the context of host-pathogen interactions.