The central goal of Dr. Asch's research is to uncover the mechanistic underpinnings of how stress and trauma affect brain function, with a particular emphasis on how these experiences shape mental health outcomes with the aim to contribute to the development of novel interventions designed to mitigate the harmful effects of stress and trauma, foster resilience, and ultimately improve overall 
health and well-being.

The Douglas lab seeks to understand how stress response pathways alter cell physiology, and ultimately influence the aging process and human disease.