The Bartelt Lab is focused on understanding the epigenetic basis of cerebellar neurodegenerative disorders to develop holistic gene therapies. Using single-cell and spatial sequencing approaches, we profile healthy and diseased states to identify gene regulatory mechanisms in disease and utilize functional genomic tools to advance therapeutic approaches. 

The central goal of Dr. Asch's research is to uncover the mechanistic underpinnings of how stress and trauma affect brain function, with a particular emphasis on how these experiences shape mental health outcomes with the aim to contribute to the development of novel interventions designed to mitigate the harmful effects of stress and trauma, foster resilience, and ultimately improve overall 
health and well-being.

The Sankary Neuroethics Lab at UT Southwestern explores the ethical dimensions of neuroscience and neurosurgical innovation.

Dr. Brunoni's research focuses on developing innovative therapeutic strategies using transcranial direct current stimulation, transcranial magnetic stimulation, and other neuromodulation techniques for treating major depressive disorder, bipolar disorder, OCD, schizophrenia, and post-COVID cognitive symptoms.

Understanding brain circuits in disease and cognition to develop restorative neuromodulation. 

Our research focuses on genetic epilepsy and will help us understand the roles of genes such as ASH1L and SLC13A5 through clinical patient studies and mouse models, advancing treatment options for these disorders and deepening the understanding of epilepsy.

The Liu Lab studies the seasonal clock and its roles in human health. We use a new seasonal primate model, the mouse lemur, and an interdisciplinary approach of molecular biology, genetics, omics, machine learning, and computational modeling. We also apply the mouse lemur primate model to study pathophysiology that is poorly represented in mice, with a focus on neurodegeneration, immunology, and metabolism.

The Ortiz Lab develops advanced mathematical models and AI-driven approaches to understanding mood disorders as dynamic biological systems, works on nonlinear analysis of mood regulation, and integrates wearable technology with personalized treatment frameworks.

The Rosa-Neto Lab studies the structural changes that occur in the brain as a result of neurodegenerative disease, such as Alzheimer’s disease. 

The Davenport Lab focuses on quantitative methods for human brain imaging, primarily using MRI and Magnetoencephalography (MEG).