Khorsandi S, Huntoon K, Wang Y, Woodward A, Antony A, Endsley C, Hafeez N, Edwards JL, McCuen N, Alluri PG, Kim BYS, Jiang W, Lux J. Targeted STING Activation Using Modified Ultrasound-Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma. Adv Sci (Weinh). 2025 Mar 26:e2416596. doi: 10.1002/advs.202416596. Epub ahead of print. PMID: 40135812.
Gao R, Wang E, Pineiro V, Chudal L, Santelli J, Endsley C, Woodward A, de Gracia Lux C, Lux J, Mattrey RF. Perfluorohexane Emulsions Induce Macrophage-Stimulating Effects through iNOS Expression. ACS Appl Bio Mater. 2025 Apr 11. doi: 10.1021/acsabm.5c00191. Epub ahead of print. PMID: 40215334.
Endsley C, Ali S, Salhadar K, Woodward A, Garland S, Santelli J, Salimabad MZ, Ren L, Yokoo T, Rosado-Mendez IM, Fetzer DT, de Gracia Lux C. Lipid Microparticle-Based Phantoms Modeling Hepatic Steatosis for the Validation of Quantitative Imaging Techniques. Small Methods. 2025 Apr 25:e2500043. doi: 10.1002/smtd.202500043. Epub ahead of print. PMID: 40277165.
2024
Ali S, de Gracia Lux C, Brown K, Endsley C, Woodward A, Mattrey R, Lux J*. Modulating Nonlinear Acoustic Response of Phospholipid-Coated Microbubbles with pH for Ultrasound Imaging. ACS Sens. 2024 May 16. doi: 10.1021/acssensors.3c02382. Epub 2024 May 16. PMID: 38752383
Khorsandi S, Huntoon K, Lux, J. Putting the sting back in STING therapy: novel delivery vehicles for improved STING activation. Front Chem Biol 2024. https://doi.org/10.3389/fchbi.2024.1386220
Gao R, Wang E, Pineiro V, Chudal L, Santelli J, Endsley C, Woodward A, de Gracia Lux C, Lux J, Mattrey RF. Perfluorohexane Emulsions Induce Macrophage-Stimulating Effects through iNOS Expression. ACS Appl Bio Mater. 2025 Apr 11. doi: 10.1021/acsabm.5c00191. Epub ahead of print. PMID: 40215334.
2023
Chudal L, Santelli J, Lux J, Woodward A, Hafeez N, Endsley C, Garland S, Mattrey RF, de Gracia Lux C. In Vivo Ultrasound Imaging of Macrophages Using Acoustic Vaporization of Internalized Superheated Nanodroplets. ACS Appl Mater Interfaces. 2023 Sep 13;15(36):42413-42423. doi: 10.1021/acsami.3c11976. Epub 2023 Aug 31. PMID: 37650753.
Lee D, Huntoon K, Lux, J, Kim BYS, Jiang W. Engineering nanomaterial physical characteristics for cancer immunotherapy. Nat Rev Bioeng 2023. https://doi.org/10.1038/s44222-023-00047-3.
2022
Li X, Khorsandi S, Wang Y, Santelli J, Huntoon K, Nguyen N, Yang M, Lee D, Lu Y, Gao R, Kim BYS, de Gracia Lux C, Mattrey RF, Jiang W*, Lux J*. Cancer immunotherapy based on image-guided STING activation by nucleotide nanocomplex-decorated ultrasound microbubbles. Nat Nanotechnol. 2022 Aug;17(8):891-899. doi: 10.1038/s41565-022-01134-z. Epub 2022 May 30.
2021
Heble AY, Santelli J, Armstrong AM, Mattrey RF, Lux J. Catalase-Loaded Silica Nanoparticles Formulated via Direct Surface Modification as Potential Oxygen Generators for Hypoxia Relief. ACS Appl Mater Interfaces. 2021 Feb 10;13(5):5945-5954. doi: 10.1021/acsami.0c19633. Epub 2021 Jan 26.
2020
Burns MWN, Mattrey RF, Lux J. Microbubbles Cloaked with Hydrogels as Activatable Ultrasound Contrast Agents. ACS Appl Mater Interfaces. 2020 Nov 25;12(47):52298-52306. doi: 10.1021/acsami.0c12043. Epub 2020 Nov 10.
Brambila CJ, Lux J, Mattrey RF, Boyd D, Borden MA, de Gracia Lux C. Bubble Inflation Using Phase-Change Perfluorocarbon Nanodroplets as a Strategy for Enhanced Ultrasound Imaging and Therapy. Langmuir. 2020 Mar 24;36(11):2954-2965.
2019
Malone CD, Fetzer DT, Lux J, Mattrey RF. Catalase-Containing Silica Particles as Ultrasound-Based Hydrogen Peroxide Sensors to Determine Infected From Noninfected Fluid Collections in Humans. AJR Am J Roentgenol. 2019 Mar 12.
2018
Lux J, Sherry AD. Advances in gadolinium-based MRI contrast agent designs for monitoring biological processes in vivo. Curr Opin Chem Biol. 2018 Aug;45:121-130. doi:10.1016/j.cbpa.2018.04.006. Epub 2018 May 9. PMID: 29751253. PMCID: PMC6076858.
2017
de Gracia Lux C*, Vezeridis AM, Lux J, Armstrong AM, Sirsi SR, Hoyt K, Mattrey RF*. Novel method for the formation of monodisperse superheated perfluorocarbon nanodroplets as activatable ultrasound contrast agents. RSC Adv., 2017, 7, 48561-48568.
Lux J*, Vezeridis AM, Hoyt K, Adams SR, Armstrong AM, Sirsi SR, Mattrey RF*. Thrombin-Activatable Microbubbles as Potential Ultrasound Contrast Agents for the Detection of Acute Thrombosis. ACS Appl Mater Interfaces. 2017, 9(43), 37587-37596.