Publications

The PIK3CA/AKT pathway drives therapy resistance in rhabdomyosarcoma

Yang Q, Wang Y, Corchete Sanchez LA, Mathavarajah S, Qin Q, Wei Y, Alpert E, Whelton L, Sharma P, Strom S, Oultache I, Iafrate AJ, Pinello L, Rheinbay E, Yan C, Langenau DM 2026 Dec Nature communications 17

Biological Advances and Current Challenges for Pediatric Rhabdomyosarcoma

Hebron KE, Odeniyide P, Wei Y, Gryder BE, Barr FG, Casey DL, Chen EY, Crompton BD, Dela Cruz FS, Durbin AD, Ford HL, Gatz SA, Hatley ME, Henssen AG, Hettmer S, Houghton PJ, Kendall GC, Khan J, Lupo PJ, Patel AG, Pomella S, Rota R, Schito M, Schoot RA, Shern JF, Stanton BZ, Stewart EA, Swindlehurst CA, Thomas CJ, Vakoc CR, Vaseva AV, Venkatramani R, Wexler LH, Yustein JT, Hammond S, Heske CM, Langenau DM, Linardic CM, Ignatius MS, Yohe ME 2026 Mar Cancers 18

Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma

Danielli SG, Wei Y, Dyer MA, Stewart E, Sheppard H, Wachtel M, Schäfer BW, Patel AG, Langenau DM 2024 Dec Nature communications 15

Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma

Wei Y, Qin Q, Yan C, Hayes MN, Garcia SP, Xi H, Do D, Jin AH, Eng TC, McCarthy KM, Adhikari A, Onozato ML, Spentzos D, Neilsen GP, Iafrate AJ, Wexler LH, Pyle AD, Suvà ML, Dela Cruz F, Pinello L, Langenau DM 2022 Aug Nature Cancer 3 961-975

Single-cell imaging of T cell immunotherapy responses in vivo

Yan C, Yang Q, Zhang S, Millar DG, Alpert EJ, Do D, Veloso A, Brunson DC, Drapkin BJ, Stanzione M, Scarfò I, Moore JC, Iyer S, Qin Q, Wei Y, McCarthy KM, Rawls JF, Dyson NJ, Cobbold M, Maus MV, Langenau DM 2021 Aug Journal of Experimental Medicine 218

Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma

Maximov V, Chen Z, Wei Y, Robinson MH, Herting CJ, Shanmugam NS, Rudneva VA, Goldsmith KC, MacDonald TJ, Northcott PA, Hambardzumyan D, Kenney AM 2019 Dec Nature communications 10

P53 function is compromised by inhibitor 2 of phosphatase 2A in sonic hedgehog medulloblastoma

Wei Y, Maximov V, Morrissy SA, Taylor MD, Pallas DC, Kenney AM 2019 Jan Molecular Cancer Research 17 186-198

Structural transitions of centromeric chromatin regulate the cell cycle-dependent recruitment of CENP-N

Fang J, Liu Y, Wei Y, Deng W, Yu Z, Huang L, Teng Y, Yao T, You Q, Ruan H, Chen P, Xu RM, Li G 2015 Genes and Development 29 1058-1073