Featured Publications
Shahanshah Khan, Youn-Tae Kwak, Lan Peng, Shuiqing Hu, Brandi L. Cantarel, Cheryl M. Lewis, Yunpeng Gao, Ram S. Mani , Thirumala-Devi Kanneganti, and Hasan Zaki
2023
SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-kB pathway
Shahanshah Khan, Mahnoush S. Shafiei, Christopher Longoria, John Schoggins, Rashmin C. Savani, Hasan Zaki 2021 eLife 2021;10:e68563
Chuanhui Han, Victoria Godfrey, Zhida Liu, Yanfei Han, Longchao Liu, Hua Peng, Ralph W, Weichselbaum, Hasan Zaki*, Yang-Xin Fu*. * co-correspondence
2021
59
6
Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice
Shahanshah Khan, Sumyya Waliullah, Victoria Godfrey, Md Abdul Wadud Khan, Rajalaksmy A Ramachandran, Brandi L. Cantarel, Cassie Behrendt, Lan Peng, Lora V. Hooper, and Hasan Zaki 2020
SM Nashir Udden, Youn-tae Kwak, Victoria Godfrey, Md Abdul Wadud Khan, Shahanshah Khan, Nicolas Loof, Lan Peng, Hao Zhu, Md Hasan Zaki
2019
NOD2 Suppresses Colorectal Tumorigenesis via Downregulation of the TLR Pathways.
Udden SMN, Peng L, Gan JL, Shelton JM, Malter JS, Hooper LV, Zaki MH 2017 Jun Cell Rep 13 19 2756-2770
Hu S, Peng L, Kwak YT, Tekippe EM, Pasare C, Malter JS, Hooper LV, Zaki MH
2015 Dec
Cell Rep
9
13
1922-36
Zaki MH, Man SM, Vogel P, Lamkanfi M, Kanneganti TD
2014 Jan
Proc. Natl. Acad. Sci. U.S.A.
1
111
385-90
The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.
Zaki MH, Vogel P, Malireddi RK, Body-Malapel M, Anand PK, Bertin J, Green DR, Lamkanfi M, Kanneganti TD 2011 Nov Cancer Cell 5 20 649-60The Nlrp3 inflammasome: contributions to intestinal homeostasis.
Zaki MH, Lamkanfi M, Kanneganti TD 2011 Apr Trends Immunol. 4 32 171-9
Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD
2010 Mar
Immunity
3
32
379-91
Protein S-guanylation by the biological signal 8-nitroguanosine 3',5'-cyclic monophosphate.
Sawa T, Zaki MH, Okamoto T, Akuta T, Tokutomi Y, Kim-Mitsuyama S, Ihara H, Kobayashi A, Yamamoto M, Fujii S, Arimoto H, Akaike T 2007 Nov Nat. Chem. Biol. 11 3 727-35Crosstalk between NLRP12 and JNK during Hepatocellular Carcinoma.
Khan S, Zaki H, 2020 Jan Int J Mol Sci 2 21Cytosolic Nucleic Acid Sensors in Inflammatory and Autoimmune Disorders.
Khan S, Godfrey V, Zaki MH 2019 Int Rev Cell Mol Biol 344 215-253
Obaid M, Udden SMN, Deb P, Shihabeddin N, Zaki MH, Mandal SS
2018 Oct
Sci Rep
1
8
15670
Kamal AHM, Chakrabarty JK, Udden SMN, Zaki MH, Chowdhury SM
2018
8
164
The Inflammasome: Regulation of Nitric Oxide and Antimicrobial Host Defense
Rajalakshmi A. Ramachandran, Christopher Lupfer and Hasan Zaki 2018 In pressChanges in the Dielectric Spectra of Murine Colon During Neoplastic Progression
Ahmet C. Sabuncu, Jeanne Shen, Md. Hasan Zaki, Ali Beskok 2018 Biomed. Phys. Eng. ExpressThe Ex Vivo Colon Organ Culture and Its Use in Antimicrobial Host Defense Studies
Udden, S. M., Waliullah, S., Harris, M., Zaki, H. 2017 J. Vis. Exp. 120
Lukens JR, Gurung P, Shaw PJ, Barr MJ, Zaki MH, Brown SA, Vogel P, Chi H, Kanneganti TD.
2015
Drak2 is not required for tumor surveillance and suppression.
Edwards BA, Harris TL, Floersh H, Lukens JR, Zaki MH, Vogel P, Kanneganti TD, Bui JD, McGargill MA. 2015Role of inflammasomes in host defense against Citrobacter rodentium infection.
Liu Z, Zaki MH, Vogel P, Gurung P, Finlay BB, Deng W, Lamkanfi M, Kanneganti TD 2012 May J. Biol. Chem. 20 287 16955-64Inflammasome is a central player in the induction of obesity and insulin resistance.
Stienstra R, van Diepen JA, Tack CJ, Zaki MH, van de Veerdonk FL, Perera D, Neale GA, Hooiveld GJ, Hijmans A, Vroegrijk I, van den Berg S, Romijn J, Rensen PC, Joosten LA, Netea MG, Kanneganti TD 2011 Sep Proc. Natl. Acad. Sci. U.S.A. 37 108 15324-9
Zaki MH, Lamkanfi M, Kanneganti TD
2011
Drug Discov Today Dis Mech
3-4
8
e71-e78
Zaki MH, Vogel P, Body-Malapel M, Lamkanfi M, Kanneganti TD
2010 Oct
J. Immunol.
8
185
4912-20
Zaki MH, Fujii S, Okamoto T, Islam S, Khan S, Ahmed KA, Sawa T, Akaike T
2009 Mar
J. Immunol.
6
182
3746-56
Alam MS, Zaki MH, Sawa T, Islam S, Ahmed KA, Fujii S, Okamoto T, Akaike T
2008 Apr
Microbiol. Immunol.
4
52
197-208
Alam MS, Zaki MH, Yoshitake J, Akuta T, Ezaki T, Akaike T
2006 Mar
Microb. Pathog.
3
40
116-25
Nitrative stress through formation of 8-nitroguanosine: insights into microbial pathogenesis.
Akuta T, Zaki MH, Yoshitake J, Okamoto T, Akaike T 2006 Mar Nitric Oxide 2 14 101-8Nitric oxide-induced nitrative stress involved in microbial pathogenesis.
Zaki MH, Akuta T, Akaike T 2005 Jun J. Pharmacol. Sci. 2 98 117-29
Azim T, Zaki MH, Podder G, Sultana N, Salam MA, Rahman SM, Sefat-e-Khuda null, Sack DA
2003 Feb
J. Med. Virol.
2
69
286-95
Seroepidemiology of hepatitis B and delta virus infections in Bangladesh.
Zaki H, Darmstadt GL, Baten A, Ahsan CR, Saha SK 2003 Dec J. Trop. Pediatr. 6 49 371-4Join Our Lab
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