If interested in the open positions below, please contact Dr. Christoph Zechner via Email or 214-648-2868.
Job Description:
Research Scientist:
The Zechner Lab is looking to recruit a dynamic, well-trained, collegial, and team-driven research scientist to study the mechanisms that govern cellular phosphate homeostasis and sensing in mammalian species. Despite the many critical roles that phosphate has in many fundamental biological function (e.g., preservation of energy in ATP, storage of genetic information in DNA, regulatory protein phosphorylation, and skeleton formation), our knowledge on this topic is surprisingly limited. Our work is at an exciting interface between energy and mineral metabolism. Our studies employ a wide range of molecular biological, cell biological, and physiological techniques including molecular cloning of reagents for transient transfections and lentiviral infections of cultured cells, reporter assays to monitor protein translation and RNA-protein interactions, confocal microscopy, genome-wide genetic screening, and phosphate uptake assays. The main focus of our work is currently on cultured mammalian cells with complementary murine studies to follow up on critical results. We are looking for a candidate with experience especially in molecular and cell biology.
Postdoc:
The Zechner Lab in the Department of Internal Medicine/Endocrine Division is looking to recruit a dynamic, well-trained, collegial, and team-driven postdoc to study the mechanisms that govern cellular phosphate homeostasis and sensing in mammalian species. Despite the many critical roles of phosphate for many fundamental biological functions (e.g., preservation of energy in ATP, storage of genetic information in DNA, regulatory protein phosphorylation, and skeleton formation), our knowledge on this topic is surprisingly limited. Our work is at an exciting interface between energy and mineral metabolism with many possible future research directions. Our studies employ on a wide range of molecular biological, cell biological, and physiological techniques including molecular cloning of reagents for transient transfections and lentiviral infections of cultured cells, reporter assays to monitor protein translation and RNA-protein interactions, confocal microscopy, genome-wide genetic screening, and phosphate uptake assays. The main focus of our work is currently on cultured mammalian cells with complementary murine studies to follow up on critical results. We are looking to recruit a candidate with a recent M.D. and/or Ph.D. degree, experience in molecular and cell biological techniques, and first author publications.