Research

Dr. Aroumougame's Research Interests

DNA damage response signaling in carcinogenesis
DNA repair factors in immune response and immunotherapy
DNA replication in tumorigenesis
Pathophysiology of premature aging syndrome, specifically Werner Syndrome Protein
Radiotherapy and heart damage
Space radiation and astronauts' health

Werner syndrome protein and DNA replication
Werner syndrome protein protects replication of genomic DNA to prevent carcinogenesis.

Space radiation
and DNA lesions
Ionizing tracks traversed by space radiation generate complex DNA lesions in the human genome.

Cancer therapeutics and cardiac toxicity
DNA damage response factors in cancer therapeutics-induced heart regeneration.

DNA repair factors and immunotherapy
Triggering innate immune signaling to kill cancer cells in response to genotoxic cancer therapeutics.