Meet the PI
Nikolaos Louros, Ph.D.
Principal Investigator
Dr. Nikolaos Louros is an Assistant Professor of Biophysics at the Center for Alzheimer’s and Neurodegenerative Diseases (CAND) at the O’Donnell Brain Institute at UT Southwestern Medical School. He is an Endowed Scholar of UTSW ("Thomas O. Hicks Scholar in Medical Research"). He also holds a secondary appointment with the Department of Biophysics at UTSW and is part of the Peter O'Donnell Jr. Brain Institute (OBI) Investigator Program. He earned his BSc in Biology, MSc in Bioinformatics, and PhD in Molecular Biophysics from the National and Kapodistrian University of Athens (Greece), where he worked on studying the misfolding and assembly mechanisms of various proteins associated with the formation of pathological and functional amyloids.
Nikos' postdoctoral work took place at the VIB-KU Leuven Center for Brain & Disease Research, where he contributed to the development of several tools for the assessment of protein stability and aggregation. His postdoctoral work also revealed the impact of heterotypic interactions between amyloids and other biomolecules both in function and disease, with emphasis on proteins associated with major neurodegenerative disorders, such as Alzheimer's disease. Harvesting this knowledge, he has worked on developing anti-amyloid therapeutics agents.
Meet the Team
Katerina Konstantoulea, Ph.D.
Postdoctoral Researcher
I received my Bachelor's degree in Chemistry from the University of Ioannina, followed by a Master’s in Molecular and Cellular Life Sciences from Utrecht University. I earned my PhD in Biomedical Sciences from KU Leuven where I focused on sequence-based interactions of Aβ42 in aggregation. I continued as a Postdoctoral researcher at Switch Lab in KU Leuven- VIB where I investigated the interactions of Aβ42 with disease-relevant proteins. I am passionate about unravelling the complexities of protein aggregation, from molecular intricacies to cellular dynamics and broader regional impacts. In the Louros lab, my interest in heterotypic interactions of brain amyloids guides my research towards gaining meaningful insights into the mechanisms of neurodegenerative diseases, with the ultimate goal of contributing to the development of targeted therapies.
Joining Soon!
Research Associate
Our lab is looking for a new member to join as an experienced research associate! Are you interested?
Please contact Dr. Louros by Email.
What about You? Join our Team!
We are newly established at the Center for Alzheimer's and Neurodegenerative Diseases, part of the Peter O'Donnell Jr. Brain Institute at UT Southwestern Medical Center. The Louros lab also holds a secondary affiliation to the Department of Biophysics at UT Southwestern Medical Center.
Our group is growing quickly, and we are currently accepting graduate students and postdoctoral scientists. We welcome qualified applicants from all backgrounds
Postdocs
Please email Dr. Louros with your CV and a brief description of your scientific interests and research goals.
Graduate Students
Potential graduate students at UT Southwestern apply and are accepted via the Graduate School of Biomedical Sciences. Once admitted, they typically take the one-semester Core Course and join individual Ph.D. programs during the second semester.
If you are already a UTSW graduate student and are interested in joining the lab, email Dr. Louros or drop by his office in the Center for Alzheimer's and Neurodegenerative Diseases (NS8.314).
- Do you have expertise that could help us?
- Are you interested in expanding your skillset?
- Are you a motivated and curious researcher with interesting ideas you want to pursue?
Contact Dr. Louros about joining the lab!