Welcome to the Louros Lab website!
Integrating deep learning protein engineering with molecular biophysics, cellular, and structural biology to investigate protein stability, misfolding and aggregation
The Louros Lab focuses on uncovering the determining molecular forces related to protein folding, stability, and misfolding and understanding their impact on function and disease. Another facet of these important biological questions involves the process of protein self-assembly into ordered amyloid fibrils, which are the main hallmark of major neurodegenerative diseases, such as Alzheimer's and Parkinson's disease.
To do this, we employ a hybrid approach combining AI-based protein engineering methods with experimental validation, using biochemistry, biophysics, cellular and structural biology.
What about You? Join our Team!
We are newly established at the Center for Alzheimer's and Neurodegenerative Diseases, part of the Peter O'Donnell Jr. Brain Institute at UT Southwestern Medical Center. The Louros lab also holds a secondary affiliation to the Department of Biophysics at UT Southwestern Medical Center.
Our group is growing quickly, and we are currently accepting graduate students and postdoctoral scientists. We welcome qualified applicants from all backgrounds
Postdocs
Please email Dr. Louros with your CV and a brief description of your scientific interests and research goals.
Graduate Students
Potential graduate students at UT Southwestern apply and are accepted via the Graduate School of Biomedical Sciences. Once admitted, they typically take the one-semester Core Course and join individual Ph.D. programs during the second semester.
If you are already a UTSW graduate student and are interested in joining the lab, email Dr. Louros or drop by his office in the Center for Alzheimer's and Neurodegenerative Diseases (NS8.314).
- Do you have expertise that could help us?
- Are you interested in expanding your skillset?
- Are you a motivated and curious researcher with interesting ideas you want to pursue?
Contact Dr. Louros about joining the lab!