Publications

RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice.

Zhong X, Choi JH, Hildebrand S, Ludwig S, Wang J, Nair-Gill E, Liao TC, Moresco JJ, Liu A, Quan J, Sun Q, Zhang D, Zhan X, Choi M, Li X, Wang J, Gallagher T, Moresco EMY, Beutler B, 2022 May Proc Natl Acad Sci U S A 18 119 e2200128119

Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning.

Xu D, Lyon S, Bu CH, Hildebrand S, Choi JH, Zhong X, Liu A, Turer EE, Zhang Z, Russell J, Ludwig S, Mahrt E, Nair-Gill E, Shi H, Wang Y, Zhang D, Yue T, Wang KW, SoRelle JA, Su L, Misawa T, McAlpine W, Sun L, Wang J, Zhan X, Choi M, Farokhnia R, Sakla A, Schneider S, Coco H, Coolbaugh G, Hayse B, Mazal S, Medler D, Nguyen B, Rodriguez E, Wadley A, Tang M, Li X, Anderton P, Keller K, Press A, Scott L, Quan J, Cooper S, Collie T, Qin B, Cardin J, Simpson R, Tadesse M, Sun Q, Wise CA, Rios JJ, Moresco EMY, Beutler B, 2021 Jul Proc Natl Acad Sci U S A 28 118

Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.

Zhong X, Su L, Yang Y, Nair-Gill E, Tang M, Anderton P, Li X, Wang J, Zhan X, Tomchick DR, Brautigam CA, Moresco EMY, Choi JH, Beutler B, 2020 Mar Proc. Natl. Acad. Sci. U.S.A.

Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation.

Misawa T, SoRelle JA, Choi JH, Yue T, Wang KW, McAlpine W, Wang J, Liu A, Tabeta K, Turer EE, Evers B, Nair-Gill E, Poddar S, Su L, Ou F, Yu L, Russell J, Ludwig S, Zhan X, Hildebrand S, Li X, Tang M, Murray AR, Moresco EMY, Beutler B, 2020 Jan Sci Immunol 43 5

Adenosine monophosphate deaminase 3 null mutation causes reduction of naive T cells in mouse peripheral blood.

Zhan X, Zhong X, Choi JH, Su L, Wang J, Nair-Gill E, Anderton P, Li X, Tang M, Russell J, Ludwig S, Gallagher T, Beutler B, 2020 Aug Blood Adv 15 4 3594-3605

Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40.

Zhang D, Yue T, Choi JH, Nair-Gill E, Zhong X, Wang KW, Zhan X, Li X, Choi M, Tang M, Quan J, Hildebrand S, Moresco EMY, Beutler B, 2019 Aug Nat. Immunol.

LMBR1L regulates lymphopoiesis through Wnt/?-catenin signaling.

Choi JH, Zhong X, McAlpine W, Liao TC, Zhang D, Fang B, Russell J, Ludwig S, Nair-Gill E, Zhang Z, Wang KW, Misawa T, Zhan X, Choi M, Wang T, Li X, Tang M, Sun Q, Yu L, Murray AR, Moresco EMY, Beutler B, 2019 05 Science 6440 364

Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver.

Clark PM, Flores G, Evdokimov NM, McCracken MN, Chai T, Nair-Gill E, O'Mahony F, Beaven SW, Faull KF, Phelps ME, Jung ME, Witte ON 2014 Jun Proc. Natl. Acad. Sci. U.S.A.

Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance.

Bunimovich YL, Nair-Gill E, Riedinger M, McCracken MN, Cheng D, McLaughlin J, Radu CG, Witte ON, 2014 PLoS One 8 9 e104125

Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene.

McCracken MN, Gschweng EH, Nair-Gill E, McLaughlin J, Cooper AR, Riedinger M, Cheng D, Nosala C, Kohn DB, Witte ON, 2013 Jan Proc Natl Acad Sci U S A 5 110 1857-62

Visualizing cancer and immune cell function with metabolic positron emission tomography.

Laing RE, Nair-Gill E, Witte ON, Radu CG, 2010 Feb Curr Opin Genet Dev 1 20 100-5

Epithelial uptake of [18F]1-(2'-deoxy-2'-arabinofuranosyl) cytosine indicates intestinal inflammation in mice.

Brewer S, Nair-Gill E, Wei B, Chen L, Li X, Riedinger M, Campbell DO, Wiltzius S, Satyamurthy N, Phelps ME, Radu C, Witte ON, Braun J, 2010 Apr Gastroenterology 4 138 1266-75

Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2'-deoxycytidine analog.

Radu CG, Shu CJ, Nair-Gill E, Shelly SM, Barrio JR, Satyamurthy N, Phelps ME, Witte ON, 2008 Jul Nat Med 7 14 783-8

Non-invasive imaging of adaptive immunity using positron emission tomography.

Nair-Gill ED, Shu CJ, Radu CG, Witte ON 2008 Feb Immunol. Rev. 221 214-28

Assaying Bcr-Abl kinase activity and inhibition in whole cell extracts by phosphorylation of substrates immobilized on agarose beads.

Wu D, Nair-Gill E, Sher DA, Parker LL, Campbell JM, Siddiqui M, Stock W, Kron SJ, 2005 Dec Anal Biochem 1 347 67-76