Publications 2010 and Prior

Discovery of a proneurogenic, neuroprotective chemical.
Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM, Becker GL, Huntington P, Goldman SE, Shen CH, Capota M, Britt JK, Kotti T, Ure
K, Brat DJ, Williams NS, MacMillan KS, Naidoo J, Melito L, Hsieh J, De Brabander J, Ready JM, McKnight SL. Cell. 2010 Jul 142 39-51.

 

Discovery of a proneurogenic, neuroprotective chemical

Deconvolution of complex NMR spectra in small molecules by multi frequency homonuclear decoupling (MDEC).
Espindola AP, Crouch R, DeBergh JR, Ready JM, MacMillan JB. J Am Chem Soc. 2009 Nov 131 15994-5.

Allenes in asymmetric catalysis: asymmetric ring opening of meso-epoxides catalyzed by allene-containing phosphine oxides.
Pu X, Qi X, Ready JM. J Am Chem Soc. 2009 Aug 131 10364-5

 

Allenes in asymmetric catalysis

Synthesis of cyclopentenones from cyclopropanes and silyl ynol ethers.
Qi X, Ready JM. Angew Chem Int Ed Engl. 2008 47 7068-70.

 

Synthesis of cyclopentenones from cyclopropanes and silyl ynol ethers

Direct and stereospecific synthesis of allenes via reduction of propargylic alcohols with Cp2Zr(H)Cl.
Pu X, Ready JM. J Am Chem Soc. 2008 Aug 130 10874-5.

 

Direct and stereospecific synthesis of allenes via reduction of propargylic alcohols with Cp2Zr(H)Cl

Preparation of substituted enol derivatives from terminal alkynes and their synthetic utility.
DeBergh JR, Spivey KM, Ready JM. J Am Chem Soc. 2008 Jun 130 7828-9.

 

Preparation of substituted enol derivatives from terminal alkynes and their synthetic utility

Directed Hydrozirconation of Homopropargylic Alcohols.
Liu X, Ready JM. Tetrahedron. 2008 64 6955-6960.

 

Directed Hydrozirconation of Homopropargylic Alcohols

Directed hydrozirconation of propargylic alcohols.
Zhang D, Ready JM. J Am Chem Soc. 2007 Oct 129 12088-9.

 

Directed hydrozirconation of propargylic alcohols

Discovery of small-molecule inhibitors of tyrosinase.
Germanas JP, Wang S, Miner A, Hao W, Ready JM. Bioorg Med Chem Lett. 2007 Dec 17 6871-5.

Copper-promoted cycloaddition of diazocarbonyl compounds and acetylides.
Qi X, Ready JM. Angew Chem Int Ed Engl. 2007 46 3242-4.

 

Copper-promoted cycloaddition of diazocarbonyl compounds and acetylides

Iron-catalyzed carbometalation of propargylic and homopropargylic alcohols.
Zhang D, Ready JM. J Am Chem Soc. 2006 Nov 128 15050-1.

Iron-catalyzed carbometalation of propargylic and homopropargylic alcohols

Enantioselective total synthesis of (+)- and (-)-nigellamine A2.
Bian J, Van Wingerden M, Ready JM. J Am Chem Soc. 2006 Jun 128 7428-9.

Enantioselective total synthesis of (+)- and (-)-nigellamine A2

Tandem carbocupration/oxygenation of terminal alkynes.
Zhang D, Ready JM. Org Lett. 2005 Dec 7 5681-3.

Tandem carbocupration/oxygenation of terminal alkynes

Catalytic cross-coupling of alkylzinc halides with alpha-chloroketones.

Malosh CF, Ready JM. J Am Chem Soc. 2004 Aug 126 10240-1.

Catalytic cross-coupling of alkylzinc halides with alpha-chloroketones