Our lab conducts translational research that seeks to uncover mysteries of cancer and develop powerful methods for its detection and cure.
To achieve universal tumor targeting, we have been working with ubiquitous tumor markers, or “hallmarks of cancer.” We have shown that targeting two such hallmarks, angiogenesis and the acidic tumor extracellular microenvironment, allows for imaging of a wide variety of cancers using fluorescence. We have subsequently discovered that the acidic cancer microenvironment can be imaged in a way that enhances information provided to surgeons.
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