The Robertson Lab studies mitochondrial and metabolic homeostasis in the corneal epithelium and the role of homeostatic dysfunction in the pathophysiology of corneal disease.

The Tong lab studies the cellular and molecular mechanisms of cardiovascular diseases associated with systemic metabolic disorders, particularly heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF), with an eye toward translating these findings into innovative solutions to clinical problems.

The Mendell laboratory investigates fundamental aspects of post-transcriptional gene regulation, noncoding RNA regulation and function, and the roles of these pathways in normal physiology, cancer, and other diseases.

Buszczak laboratory seeks to gain new insights into mRNA translation, ribosome biogenesis and germ cell biology 

Located in the Department of Ophthalmology, the Wert laboratory studies the post-mitotic neuronal cells of the retina, particularly the photoreceptor cells. Our goal is to discover and understand the mechanisms underlying retinal degenerative disease, and to provide novel therapeutics for these complex degenerative disorders using gene therapy and genome engineering technologies, human stem cell transplantations, and metabolic rescue.

Our lab currently studies hypoxia, prolyl hydroxylase, and VHL signaling in cancer, especially breast and renal cell carcinomas.

Our lab focuses on the molecular and cellular mechanisms underlying cell fate specification during blood vessel development and organogenesis.